Dimyristoylphosphatidylglycerol
Grundinformationen
- CAS
61361-72-6- Standard-SMILES
CCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCC(O)CO)OC(=O)CCCCCCCCCCCCC- InChIKey
BPHQZTVXXXJVHI-UHFFFAOYSA-N- Summenformel
- C34H67O10P
- Durchschnittliche Molmasse
- 666,9 g/mol
- Monoisotopische Masse
- 666,44718533
Überblick
DL-dimyristoylphosphatidylglycerol is a phospholipid used in commercially available pharmaceutical preparations to solubilize drugs for injection.
Namen und Bezeichner
- Bevorzugter Name
- Dimyristoylphosphatidylglycerol
- IUPAC
- [3-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxy-2-tetradecanoyloxypropyl] tetradecanoate
- Englischer Name
- dimyristoylphosphatidylglycerol
- Summenformel
- C34H67O10P
- Molmasse
- 666.86
Namen und Synonyme
DimyristoylphosphatidylglycerolDMPG61361-72-6DIMYRISTOYLPHOSPHATIDYLGLYCEROL, DL-BI71WT9P3RDimyristoyl phosphatidylglycerolTetradecanoic acid, 1-((((2,3-dihydroxypropoxy)hydroxyphosphinyl)oxy)methyl)-1,2-ethanediyl esterRefChem:5899401,2-dimyristoyl-sn-glycerol-3-phosphoglycerolDL-dimyristoylphosphatidylglycerol3-(((2,3-Dihydroxypropoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoateUNII-BI71WT9P3R
Weitere Namen anzeigen
3-{[(2,3-dihydroxypropoxy)(hydroxy)phosphoryl]oxy}-2-(tetrad...[1-(2,3-Dihydroxypropoxyhydroxyphosphoryl)oxy-3-tetradecanoyloxypropan-2-yl][1-(2,3-dihydroxypropoxy-hydroxyphosphoryl)oxy-3-tetradecanoyloxypropan-2-yl]tetradecanoateTetradecanoic acid 1-((((2,3-dihydroxypropoxy)hydroxyphosphinyl)oxy)methyl)-1,2-ethanediyl esterTetradecanoic acid, 1,1'-[1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl] ester
ALF component DMPGALFQ component DMPG14:0 PGDMPG, DL-[3-[2,3-dihydroxypropoxy(hydroxy)phosphoryl]oxy-2-tetradecanoyloxypropyl] tetradecanoateSCHEMBL12312159DTXSID80976890BPHQZTVXXXJVHI-UHFFFAOYSA-N
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 10
- Polarare Oberfläche (TPSA)
- 149 Ų
- H-Brücken-Donoren
- 3
- H-Brücken-Akzeptoren
- 10
- Frei drehbare Bindungen
- 36
- Schwere Atome
- 45
- Formalladung
- 0
- Komplexität
- 736
Physikochemische Eigenschaften
- Siedepunkt
- 725.9 · 725.9±70.0 °C(Predicted)
- Dichte
- 1.063 · 1.063
- pka
- 1.39 · 1.39±0.50(Predicted)
Chemie und Industrie
Pharmakologische Informationen
PharmacodynamicsDL-dimyristoylphosphatidylglycerol is a water soluble phospholipid used to solubilize drugs for injection.
Mechanism of Action
As a phospholipid, DL-dimyristoylphosphatidylglycerol can form a micelle with a hydrophobic core to contain lipophilic drugs while maintaining a hyrophilic outer portion to allow increased solubility of the drug in the aqueous environment of the blood or gastrointestinal tract.
Anbieter5 Anbieter
Suzhou ARTK Medchem Co., Ltd.+86-18168183658 · [email protected]
南京多隆生物科技有限公司18905173768 · [email protected]
Nanjing Dolon Biotechnology Co.,Ltd.18905173768 · [email protected]
Jilin Chinese Academy of Sciences-yanshen Technology18143011203 · [email protected]
Hefei TNJ Chemical Industry Co.,Ltd.+86-0551-65418671 +86-189 4982 3763 · [email protected]
Ergänzende Hinweise
DefinitionChEBI: A phosphatidylglycerol in which the phosphatidyl acyl groups are both myristoyl.
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