HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Bis(pyridine)iodonium tetrafluoroborate
IPY2BF4 · Barluengas · BARLUENGA'S REAGENT · SKL215 · iodanium · BarluengaReagentIpy2Bf4 · Barluenga’S Reagent Ipy2Bf4 · iodonium pyridine tetrafluoroborate
Identifikatoren & physikalische Daten
| CAS No. | 15656-28-7 |
|---|---|
| Summenformel | C10H12BF4IN2 |
| Durchschnittliche Molmasse | 373,93 g/mol |
| Monoisotopische Masse | 374,00744 g/mol |
| SMILES | F[B-](F)(F)F.[IH2+].c1ccncc1.c1ccncc1 |
| InChIKey | WVXJCTSZJWIBQT-UHFFFAOYSA-N |
| PubChem CID | 10883201 |
| EC No. | 628-405-3 |
| DTXSID | DTXSID50447027 |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 25,8 |
|---|---|
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 7 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 18 |
| Formalladung | 0 |
| Komplexität | 50 |
| Schmelzpunkt | 137-141 °C (lit.) |
| Lagerbedingungen | 2-8°C |
| Löslichkeit | sol CH2Cl2, DMSO, MeCN, pyridine, DMFmodestly sol CHCl3insol ether, THF, hexaneHydrolyzes in water. |
| Aggregatzustand | Powder |
| Farbe | Yellow |
| Merck | 14,1302 |
| BRN | 4284739 |
| InChI | 1S/2C5H5N.BF4.I/c2*1-2-4-6-5-3-12-1(3,4)5/h2*1-5H/q+1 |
| InChIKey | JBVUIHBKNVHCKK-UHFFFAOYSA-N |
| SMILES | [I+].F[B-](F)(F)F.c1ccncc1.c2ccncc2 |
| CAS Datenbank | 15656-28-7(CAS DataBase Reference) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315 (97.8%): Causes skin irritation [Warning Skin corrosion/irritation]H319 (97.8%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H335 (97.8%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 45 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| Hazard Classes and Categories | Skin Irrit. 2 (97.8%)Eye Irrit. 2 (97.8%)STOT SE 3 (97.8%) |
| Wassergefährdungsklasse (WGK) | 3 |
| UN-Transportnummer | 1759 |
| Zollcode | 29333990 |
| R-Sätze (R) | 36/37/38 |
| Gefahrensymbole | Xi,T |
| hazard_note | Toxic/Irritant |
| Sicherheitshinweise (S) | 26-36-37/39 |
| Gefahrenklasse | MOISTURE SENSITIVE, KEEP COLD, LIGHT SENSITIVEEye Irrit. 2Skin Irrit. 2STOT SE 3 |
| Verpackungsgruppe | II |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Beschreibung
Bis(pyridine)iodonium tetrafluoroborate is iodinating agent for the selective functionalization of unsaturated compounds; can also mediate C-C bond formation.
Verwenden
Bis(pyridine)iodonium tetrafluoroborate is used as mild iodinating and oxidizing reagent. It is also useful for selective iodination of free phenolic groups in tyrosine residues during solid-phase synthesis.