| GHS-Einstufung | DangerH225: Highly Flammable liquid and vapor [Danger Flammable liquids]P210, P233, P240, P241, P242, P243, P260, P264, P270, P271, P280, P284, P301+P317, P301+P330+P331, P302+P361+P354, P303+P361+P353, P304+P340, P305+P354+P338, P316, P320, P321, P330, P363, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)This chemical does not meet GHS hazard criteria for 3.7% (11 of 299) of reports.H225 (96.3%): Highly Flammable liquid and vapor [Danger Flammable liquids] |
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| Hazards Identification | Toxic/poison by inhalation (TIH/PIH) |
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| Regulatorische Informationen | Chemical: Carbonochloridic acid, ethyl esterCarbonochloridic acid, ethyl ester is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Carbonochloridic acid, ethyl ester are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 19-03-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/13646Ethoxycarbonyl chloride: HSNO Approval: HSR002989 Approved with controlsThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
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| Weitere Sicherheitsinformationen | IMAP assessments - Carbonochloridic acid, ethyl ester: Human health tier I assessment |
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| DOT-Kennzeichnung | Poison Inhalation Hazard Flammable Liquid Corrosive |
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| Brandgefahren | Special Hazards of Combustion Products: Toxic chlorine and phosgene gases may be formed in fires. (USCG, 1999)· HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.Highly flammable. Gives off irritating or toxic fumes (or gases) in a fire. Vapour/air mixtures are explosive. |
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| Brandpotenzial | DANGEROUSWHEN EXPOSED TO HEAT, FLAME, OXIDIZERSFLAMMABLE, DANGEROUS FIRE RISK |
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| Gesundheitsgefahren | Inhalation causes mucous membrane irritation, coughing, and sneezing. Vapor causes severe lachrymationliquid causes acid-type burns of eyes and skin, like those of hydrochloric acid. Ingestion causes severe burns of mouth and stomach. (USCG, 1999)· TOXIC and/or CORROSIVEinhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. |
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| Gefahrenübersicht | Corrosive to skinHighly toxic[Quick CPC] A corrosive substance that causes lacrimation and may cause lung edema after inhalation of high concentrations[ICSC] A strong irritant to skin, eyes, and respiratory tractCapable of causing severe burns to the eyes and skin[HSDB] Reacts with water[MSDSonline] See CHLOROFORMATES. |
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| DOT-Nummer und Handbuch | 1182 155 |
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| Reaktive Gruppe | Acyl Halides, Sulfonyl Halides, and Chloroformates |
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| EG-Einstufung | Symbol: F, T+R: 11-22-26-34S: (1/2)-9-16-26-28-33-36/37/39-45 |
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| UN-Einstufung | UN Hazard Class: 6.1UN Subsidiary Risks: 3 and 8UN Pack Group: I |
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| Brandbekämpfung | Excerpt from ERG Guide 155 [Substances - Toxic and/or Corrosive (Flammable / Water-Sensitive)]:Use alcohol-resistant foam, powder, carbon dioxide. NO water. In case of fire: keep cylinder cool by spraying with water. NO direct contact with water. |
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| Erste-Hilfe-Maßnahmen | Fresh air, rest. Half-upright position. Artificial respiration may be needed. Refer for medical attention.Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.Rinse mouth. Do NOT induce vomiting. Refer for medical attention . |
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| Freisetungsmaßnahmen | · CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. |
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| Erste Hilfe | INHALATION: remove to fresh airuse artificial respiration if breathing has stoppedcall a doctorkeep victim quiet and administer oxygen if needed.General First Aid: |
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| Sichere Lagerung | Fireproof. Separated from strong oxidants, food and feedstuffs and incompatible materials. See Chemical Dangers. Cool. Dry. Well closed. |
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| Firefighting Hazards | Flammable liquid. Vapors are heavier than air & may travel to a source of ignition & flash back. Combustion by-products include hydrogen chloride & other irritants & toxic gases. |
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| Expositionsschutz und Persönliche Schutzausrüstung | · Wear positive pressure self-contained breathing apparatus (SCBA).TIH (Toxic Inhalation Hazard) - Term used to describe gases and volatile liquids that are toxic when inhaled. Some are TIH materials themselves, e.g., chlorine, and some release TIH gases when spilled in water, e.g., chlorosilanes. [ERG 2016]. |
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| Brandbekämpfungsverfahren | Use dry chemical, foam, carbon dioxide, or water spray. Water may be ineffective. Use water spray to keep fire exposed containers cool. Approach fire from upwind to avoid hazardous vapors and toxic decomposition products.If material on fire or involved in fire: Do not extinguish fire unless flow can be stopped Use "alcohol" foam, dry chemical or carbon dioxide. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. |
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| Lagerbedingungen | Store in a cool, dry, well-ventilated location. Separate from acids, alkalies, amines, alcohols, oxidizing materials, & water. Normally kept refrigerated.Chloroformates should be stored in a cool, dry atmosphere. They should be transferred from containers to storage tanks or reactors through a closed system using stainless steel, or glass pump, lines and valves. |
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| Freisetung ohne Brand | Excerpt from ERG Guide 155 [Substances - Toxic and/or Corrosive (Flammable / Water-Sensitive)]: |
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| Entsorgungsverfahren | Releases may require isolation or evacuation. Eliminate all ignition sources. Stop or control the leak, if this can be done without undue risk. Use water spray to cool & disperse vapors & protect personnel. Absorb in noncombustible material for proper disposal. |
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| Verschüttetes entsorgen | Evacuate danger area! Consult an expert! Personal protection: gas-tight chemical protection suit including self-contained breathing apparatus. Ventilation. Remove all ignition sources. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in dry sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT wash away into sewer. |
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| Umweltverhalten | TERRESTRIAL FATE: Ethyl chloroformate hydrolyzes readily in water (half-life of 31.5 min at 25 °C)(1)therefore, aqueous hydrolysis will be the dominate fate process in moist soils(SRC). Ethyl chloroformate has a relatively high vapor pressure (22.4 mm Hg at 25 dec C(2)) which suggests that evaporation from dry surfaces can occur(SRC). Results of a single biodegradation study (using the Japanese MITI protocol) have classified ethyl chloroformate as biodegradable(3) but this is probably the hydrolysis product(SRC).AQUATIC FATE: Ethyl chloroformate hydrolyzes readily in water (half-life of 31.5 min at 25 °C)(1)therefore, aqueous hydrolysis will be the dominate fate process in the aquatic environment(SRC). Aqueous volatilization, bioconcentration and adsorption to sediment are not expected to be important fate processes due to ethyl chloroformate's rapid hydrolysis(SRC).ATMOSPHERIC FATE: Based upon a vapor pressure of 22.4 mm Hg at 25 °C(1), ethyl chloroformate is expected to exist primarily in the vapor phase in the ambient atmosphere(2,SRC). It will degrade in the ambient atmosphere by reaction with photochemically produced hydroxyl radicals with an estimated half-life of about 11 day(3,SRC). Since ethyl chloroformate hydrolyzes readily in water, atmospheric degradation may occur through dissolution into clouds or through contact with rain or other atmospheric water(SRC). |
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| Unerwünschte Wirkungen | Dermatotoxin - Skin burns. |
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| Expositionspfade | The substance can be absorbed into the body by inhalation and by ingestion. |
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| Signs and Symptoms | Burning sensation. Cough. Laboured breathing. Shortness of breath. Sore throat. Symptoms may be delayed.Skin burns. Blisters. Pain. Redness.Redness. Pain. Severe deep burns.Abdominal pain. Burning sensation. Shock or collapse. |
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| ICSC Environmental Data | Environmental effects from the substance have not been investigated adequately. |
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| Medical Surveillance | SPECIAL ATTENTION SHOULD BE GIVEN THE EYES & RESP TRACT IN MEDICAL EXAM. /CHLOROFORMATES/ |
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| Soil Adsorption/Mobility | Using a structure estimation method based on molecular connectivity indexes, the Koc for ethyl chloroformate can be estimated to be approximately 10(1,SRC). According to a suggested classification scheme(2), this estimated Koc value suggests that ethyl chloroformate has high mobility in soil(SRC). However, ethyl chloroformate hydrolyzes readily in water (half- life of 31.5 min at 25 °C)(3)therefore, leaching in soil is not expected to be an important fate process(SRC). |
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| Human Toxicity Excerpts | EYE IRRITATION, IRRITATION OF UPPER RESPIRATORY TRACT, & SURFACE BURNS HAVE BEEN PRINCIPAL FINDINGS IN EXPOSED HUMANS. ... EYE IRRITATION MAY PERSIST SOME TIME AFTER EXPOSURE CEASES. SKIN SENSITIZATION MAY OCCUR. /CHLOROFORMATES/... ETHYL ... CHLOROFORMATE CAN PRODUCE DELAYED PULMONARY EDEMA SIMILAR TO THAT PRODUCED BY PHOSGENE.... LACRIMATORY PROPERTIES ARE WELL-KNOWN. ... NO EFFECTS ON GENERAL HEALTH NOR IN THE LABORATORY FINDINGS (BLOOD STUDIES AND LIVER FUNCTION TESTS) OF PERSONS MANUFACTURING CHLOROFORMATES WERE NOTED. /CHLOROFORMATES/Its toxic properties resemble those of the methyl homolog in the degree of corrosiveness, irritation, and lacrimatory qualities.For more Human Toxicity Excerpts (Complete) data for ETHYL CHLOROFORMATE (7 total), please visit the HSDB record page. |
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| Artificial Pollution Sources | Ethyl chloroformate's use as a solvent in the photographic industry and as chemical intermediate(1) could result in the release of the compound to the environment through evaporation or various waste streams(SRC). |
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| Environmental Biodegradation | Using the Japanese MITI protocol (4 week incubation period with activated sludge inoculum), ethyl chloroformate was found to be biodegradable with a theoretical BOD of 81-86%(1) but this is probably the hydrolysis product(SRC). |
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| Environmental Bioconcentration | Ethyl chloroformate hydrolyzes readily in water (half-life of 31.5 min at 25 °C)(1)therefore, bioconcentration in aquatic organisms will not be an important process(SRC). |
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| Volatilization from Water/Soil | The Henry's Law constant for ethyl chloroformate can be estimated to be 3.1X10-3 atm-cu m/mole using a structure estimation method(1,SRC)this value of Henry's Law constant indicates that volatilization from water is potentially an important fate process(2). However, ethyl chloroformate hydrolyzes readily in water (half-life of 31.5 min at 25 °C)(3)therefore, volatilization from water is not expected to be important(SRC). |
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| UN-Transportnummer | UN 1182 |
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| Gefahrenklasse | 6.1 |
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| Verpackungsgruppe | I |
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