HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
6-azidohexanoic Acid
6-azidovaleric acid · e-Azidocaproic acid · 6-Azido-hexanoic acid · 6-Azidohexanoic acid >=95% · 6-Azidohexanoic acid - A1945 · Click Tag 6-Azidohexanoic acid · 6-Azidohexanoic Acid (CCT-1250)
Identifikatoren & physikalische Daten
| CAS No. | 79598-53-1 |
|---|---|
| Summenformel | C6H11N3O2 |
| Durchschnittliche Molmasse | 157,17 g/mol |
| Monoisotopische Masse | 157,0851266 g/mol |
| SMILES | [N-]=[N+]=NCCCCCC(=O)O |
| InChIKey | JCORXJUUSVCJEP-UHFFFAOYSA-N |
| PubChem CID | 11040949 |
| EC No. | 633-038-7 |
| DTXSID | DTXSID90452913 |
Chemische & physikalische Eigenschaften
| XLogP | 1,7 |
|---|---|
| Polarare Oberfläche (TPSA) | 51,7 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 4 |
| Frei drehbare Bindungen | 6 |
| Schwere Atome | 11 |
| Formalladung | 0 |
| Komplexität | 163 |
| Dichte | 1.074 g/mL |
| Brechungsindex | n/D 1.463 |
| Lagerbedingungen | 2-8°C |
| Löslichkeit | Chloroform (Slightly), Methanol (Slightly) |
| Aggregatzustand | Oil |
| Farbe | Colourless to Pale Yellow |
| Stabilität | Light Sensitive |
| InChI | InChI=1S/C6H11N3O2/c7-9-8-5-3-1-2-4-6(10)11/h1-5H2,(H,10,11) |
| InChIKey | JCORXJUUSVCJEP-UHFFFAOYSA-N |
| SMILES | C(O)(=O)CCCCCN=[N+]=[N-] |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Hazard Classes and Categories | Skin Irrit. 2 (100%) |
| Wassergefährdungsklasse (WGK) | WGK 3 |
| Zollcode | 29270000 |
| Sicherheitshinweise (S) | 24/25 |
| Lagerklasse | 11 - Combustible Solids |
| Gefahrenklasse | Eye Irrit. 2Skin Irrit. 2STOT SE 3 |
Anwendungen & Verwendung
Verwenden
6-Azidohexanoic acid is a six-carbon saturated fatty acid with an ω-terminal azide group. This building block can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC), forming a stable amide bond. The terminal azide group allows conjugation with compounds containing alkyne groups through a copper(I)-catalyzed cycloaddition reaction, also known as click chemistry. 6-Azidohexanoic acid is useful for crosslinking, synthesis of chemical probes, and other bioconjugation strategies.