Tetrahydrofuran-Boran

Borane-tetrahydrofuran

HCID 11062302CAS 14044-65-6
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Grundinformationen

Standard-SMILES
C1CCOC1.[B]
InChIKey
UWTDFICHZKXYAC-UHFFFAOYSA-N
Summenformel
C4H8BO
Durchschnittliche Molmasse
82,92 g/mol

Namen und Bezeichner

Bevorzugter Name
Borane-tetrahydrofuran
Lokaler Name
Tetrahydrofuran-Boran
Englischer Name
Borane-tetrahydrofuran complex
Summenformel
C4H11BO
Molmasse
85.94

Namen und Synonyme

14044-65-6Borane-tetrahydrofuranBorane tetrahydrofuranTetrahydrofuran boranetetrahydrofuran-boraneBoron, trihydro(tetrahydrofuran)-, (T-4)-5EAR4ERR1L(TETRAHYDROFURAN)BORANEBORANE-THF (1:1)TETRAHYDROFURAN-BORANE (1:1)TRIHYDRO(TETRAHYDROFURAN)BORANEBORON HYDRIDE (BH3)-THF (1:1)
Weitere Namen anzeigen
BH3-THFBORANE(T-4)-Trihydro(tetrahydrofuran)boronBORANE TETRAHYDROFURAN COMPLEXTrihydro(tetrahydrofuran)boronBTHFBORAN-TETRAHYDROFURANCOMPLEXBorane, 1M in tetrahydrofuranBorane-tetrahydrofurane complex
Tetrahydrofuran--boraneCCRIS 3411BoraneTHFEINECS 237-881-8RefChem:569839EC 237-881-8DTXCID201359545(T4)Trihydro(tetrahydrofuran)boron

Datenbank-Bezeichner

CAS
14044-65-6
PubChem CID
11062302
UNII
5EAR4ERR1L
EC Number
237-881-8

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA)
9,2 Ų
H-Brücken-Donoren
0
H-Brücken-Akzeptoren
1
Frei drehbare Bindungen
0
Schwere Atome
6

Experimentelle und physikochemische Eigenschaften

Chemical ClassesMetals -> Metalloid Compounds (Boron)
Density0.898 @25 °C
Physical DescriptionLiquid; [Merck Index] 10% Solution in tetrahydrofuran: Colorless liquid with an acrid odor; [Alfa Aesar MSDS]

Physikochemische Eigenschaften

Schmelzpunkt
-17 °C · -17 °C
Siedepunkt
35 °C · 35 °C
Dichte
0.898 g/mL · 0.898 g/mL at 25 °C
Flammpunkt
1 °F · 1 °F
storage temp.
20 °C · Store at <= 20°C.
Aggregatzustand
Liquid

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 5 Einträge

This chemical does not meet GHS hazard criteria for 5.9% (11 of 188) of reports.

Danger

H225 (94.1%): Highly Flammable liquid and vapor [Danger Flammable liquids]

P210, P223, P231+P232, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P335+P334, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P402+P404, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 188 reports by companies from 10 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Regulatory Information · 2 Einträge

Status: Active Update: 27-03-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/12062

Boron, trihydro(tetrahydrofuran)-, (T-4)-: Does not have an individual approval but may be used under an appropriate group standard

Hazards Summary · 1 Eintrag

Reacts violently with water; [Merck Index] 10% Solution in tetrahydrofuran (CAS# 109-99-9): Reacts violently with water evolving extremely flammable gases; May form explosive peroxides; An irritant that may cause serious eye injury; Harmful by ingestion; [Alfa Aesar MSDS] See Borane.

Hazard Classes and CategoriesFlam. Liq. 2 (94.1%)
CSL Reaction Information · 6 Einträge

CSL00083

BORANE-TETRAHYDROFURAN COMPLEX

temperatures over 40C may lead to a self-sustaining exothermic reaction—if temperature reaches 60C, a violent decomposition reaction may occur

Explosive

User-Reported

7/8/18

Sicherheit und Schutzausrüstung

Protective Action Criteria (PAC) · 3 Einträge

12 [mg/m3]

130 [mg/m3]

790 [mg/m3]

Sicherheitsdaten

F
1-10-13-34
wgk
3
tsca
TSCA listed
ridadr
UN 3399 4.3/PG 1
hs_code
29321900
risk_code
14/15-19-22-36/37/38-41-37/38-11-67-66-40-36/37

Chemie und Industrie

Verwendung und Herstellung

UsesUsed in synthetic organic chemistry; [Merck Index]
General Manufacturing InformationBoron, trihydro(tetrahydrofuran)-, (T-4)-: ACTIVE
Anwendungen · 2 Einträge

BeschreibungBorane tetrahydrofuran complex (BH3-THF) is widely used as a reducing agent in organic synthesis. It is also used as a reagent in hydroboration reactions.It is a charge-transfer complex that is a useful surrogate for diborane1 in organic synthesis. It can be used to reduce carboxylic acids to alcohols or nitriles to primary amines. It reacts with olefins to add the BH2 functional group. Alkyl- or arylboranes formed in this way can further react with unsaturated compounds such as olefins, imines, ketones, and alkynes (the hydroboration reaction) to make useful boron-containing intermediates.

VerwendenBorane-tetrahydrofuran complex is used to reduce Nylon surface amide groups to secondary amines.It is an important reagent used in the reduction of certain functional groups viz. aldehyde, ketone, carboxylic acid, amide, oxime, imine and nitrile. It is also used as hydro borating agent. It acts as a borane source for oxazaborolidine catalyzed asymmetric reductions.

Vor- und nachgelagerte Produkte

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国药集团化学试剂有限公司86-21-63210123 · [email protected]
梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
山东玖玥生物科技有限公司18853316981
爱斯特（成都）生物制药股份有限公司+86-28-85122536 85324413 · [email protected]

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