N8,N8,3-Trimethyl-2,8-phenazin-diaminmonohydrochlorid

Neutral Red

HCID 11105CAS 553-24-2

Grundinformationen

Standard-SMILES
Cc1cc2nc3ccc(N(C)C)cc3nc2cc1N.Cl
InChIKey
PGSADBUBUOPOJS-UHFFFAOYSA-N
Summenformel
C15H16N4.ClH
Durchschnittliche Molmasse
288,77 g/mol
Monoisotopische Masse
288,11417422

Überblick

Neutral red is a hydrochloride obtained by combining the free base of neutral red with one equivalent of hydrochloric acid. Neutral red acts as a pH indicator, changing from red to yellow between pH 6.8 and 8.0. It has a role as a dye, an acid-base indicator and a two-colour indicator. It contains a neutral red(1+).

Namen und Bezeichner

Bevorzugter Name
Neutral Red
IUPAC
8-N,8-N,3-trimethylphenazine-2,8-diamine;hydrochloride
Lokaler Name
N8,N8,3-Trimethyl-2,8-phenazin-diaminmonohydrochlorid
Englischer Name
Neutral Red
Summenformel
C15H16N4.ClH
Molmasse
288.78

Namen und Synonyme

NEUTRAL RED553-24-2Toluylene Red3-Amino-7-dimethylamino-2-methylphenazine hydrochlorideC.I. Basic Red 5Neutral Red chlorideMichrome No. 226Neutral Red W2,8-Phenazinediamine, N8,N8,3-trimethyl-, monohydrochlorideC.I. 50040Cerven neutralniCerven toluylenova
Weitere Namen anzeigen
Basic Red 5N2,N2,7-TriMethylphenazine-2,8-diaMine hydrochlorideKernechrotneutralredwc.i.basicred5michromeno.226cervenneutralnicervenzasadita5
C.I. Basic Red 5, monohydrochlorideCerven zasadita 5Aminodimethylaminotoluaminozine hydrochlorideNuclear Fast Red (basic dye)AI3-60242261QK3SSBHNSC-3092CHEBI:86370

Datenbank-Bezeichner

CAS
553-24-2
PubChem CID
11105
DTXSID
DTXSID90883440
ChEBI
CHEBI:86370
UNII
261QK3SSBH
EC Number
209-035-8

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA)
55 Ų
H-Brücken-Donoren
2
H-Brücken-Akzeptoren
4
Frei drehbare Bindungen
1
Schwere Atome
20

Experimentelle und physikochemische Eigenschaften

Chemical ClassesDyes -> Azine Dyes
Physical DescriptionDark green solid; [Merck Index]

Physikochemische Eigenschaften

Schmelzpunkt
290 °C · 290 °C (dec.) (lit.)
Siedepunkt
441.31 °C · 441.31°C (rough estimate)
Dichte
1.159 · 1.1590 (rough estimate)
Brechungsindex
1.611 · 1.6110 (estimate)
storage temp.
5 °C · Store at +5°C to +30°C.
Löslichkeit
2 O: · H2O: soluble10mg/mL

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 5 Einträge

This chemical does not meet GHS hazard criteria for 11.1% (2 of 18) of reports.

Warning

H315 (77.8%): Causes skin irritation [Warning Skin corrosion/irritation]

P203, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 18 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Regulatory Information · 2 Einträge

Chemical: 2,8-Phenazinediamine, N8,N8,3-trimethyl-, monohydrochloride

Phenazine, 3-amino-7-(dimethylamino)-2-methyl-, hydrochloride: Does not have an individual approval but may be used under an appropriate group standard

Hazards SummaryA skin, eye, and respiratory tract irritant; [MSDSonline]
Hazard Classes and CategoriesSkin Irrit. 2 (77.8%)

Sicherheitsdaten

wgk
3
tsca
TSCA listed
hs_code
32041300
RTECS-Nr.
SG1400000
risk_code
68-36/37/38
Toxizität
LD50 intraperitoneal in mouse: 432mg/kg

Chemie und Industrie

Pharmakologische Informationen

MeSH Pharmacological Classification · 2 Einträge

Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)

Chemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS.

Verwendung und Herstellung

UsesUsed as an indicator, biological stain, and drug; [ChemIDplus] Used to prepare neutral-red paper; [Merck Index] Azine dye; [Kirk-Othmer]
General Manufacturing Information2,8-Phenazinediamine, N8,N8,3-trimethyl-, hydrochloride (1:1): ACTIVE

Anwendungen

VerwendenNeutral Red is a common histology stain used to determine cell viability. It is also used as indicator for nitrogen determination; pH indicator; Dyes and metabolites.

Darstellung

synthetische(a) N,N-dimethyl-4-nitrosobenzenamineand 4-Methylbenzene-1,3-diaminereaction, form Toluylene Blue (Basic Dye, C.I. 49410), heating make cyclization; (b) oxidation N1,N1-dimethylbenzene-1,4-diamine, and 4-Methylbenzene-1,3-diamine mixture.

Anbieter50 Anbieter

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武汉科美沃化工有限公司+86-2785736489 +8618171418573 · [email protected]
Ergänzende Hinweise · 1 Eintrag

DefinitionChEBI: Neutral red is a hydrochloride obtained by combining the free base of neutral red with one equivalent of hydrochloric acid. Neutral red acts as a pH indicator, changing from red to yellow between pH 6.8 and 8.0. It has a role as a dye, an acid-base indicator and a two-colour indicator. It contains a neutral red(1+).

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