Grundinformationen
- Standard-SMILES
Cc1cc2nc3ccc(N(C)C)cc3nc2cc1N.Cl- InChIKey
PGSADBUBUOPOJS-UHFFFAOYSA-N- Summenformel
- C15H16N4.ClH
- Durchschnittliche Molmasse
- 288,77 g/mol
- Monoisotopische Masse
- 288,11417422
Überblick
Neutral red is a hydrochloride obtained by combining the free base of neutral red with one equivalent of hydrochloric acid. Neutral red acts as a pH indicator, changing from red to yellow between pH 6.8 and 8.0. It has a role as a dye, an acid-base indicator and a two-colour indicator. It contains a neutral red(1+).
Namen und Bezeichner
- Bevorzugter Name
- Neutral Red
- IUPAC
- 8-N,8-N,3-trimethylphenazine-2,8-diamine;hydrochloride
- Lokaler Name
- N8,N8,3-Trimethyl-2,8-phenazin-diaminmonohydrochlorid
- Englischer Name
- Neutral Red
- Summenformel
- C15H16N4.ClH
- Molmasse
- 288.78
Namen und Synonyme
Weitere Namen anzeigen
Datenbank-Bezeichner
- CAS
553-24-2- PubChem CID
- 11105
- DTXSID
DTXSID90883440- ChEBI
CHEBI:86370- UNII
- 261QK3SSBH
- EC Number
- 209-035-8
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 55 Ų
- H-Brücken-Donoren
- 2
- H-Brücken-Akzeptoren
- 4
- Frei drehbare Bindungen
- 1
- Schwere Atome
- 20
- Formalladung
- 0
- Komplexität
- 319
Experimentelle und physikochemische Eigenschaften
Physikochemische Eigenschaften
- Schmelzpunkt
- 290 °C · 290 °C (dec.) (lit.)
- Siedepunkt
- 441.31 °C · 441.31°C (rough estimate)
- Dichte
- 1.159 · 1.1590 (rough estimate)
- Brechungsindex
- 1.611 · 1.6110 (estimate)
- storage temp.
- 5 °C · Store at +5°C to +30°C.
- Löslichkeit
- 2 O: · H2O: soluble10mg/mL
- pka
- 6.7 · 6.7, 7.4(at 25℃)
- Aggregatzustand
- Solid
- Farbe
- Very dark green
- PH
- 3.1 · 3.1 (10g/l, H2O, 20℃)
- Geruch (Odor)
- Odorless
- Wasserlöslichkeit
- 50 g/L · 50 g/L
- Merck
- 14 · 14,6488
- BRN
- 3918740 · 3918740
- Stabilität
- Stable. Incompatible with strong oxidizing agents.
- Major Application
- Fuel cell power generation system, liquid crystal displays, solor cells, sensors, thermochromic materials, coloring wood, detergents, assessment of tobacco smoke, cosmetics, detect bacterial infections, multidrug resistance inhibitors, treatment of burns, endodontic, diabetes, obesity, cancer, age-related macular degeneration, viral diseases
- InChI
- 1S/C15H16N4.ClH/c1-9-6-13-15(8-11(9)16)18-14-7-10(19(2)3)4-5-12(14)17-13;/h4-8H,16H2,1-3H3;1H
- InChIKey
- PGSADBUBUOPOJS-UHFFFAOYSA-N
- SMILES
- Cl.CN(C)c1ccc2nc3cc(C)c(N)cc3nc2c1
- CAS Datenbank
- 553 · 553-24-2(CAS DataBase Reference)
- EPA chemische Informationen
- Neutral Red (553-24-2)
Sicherheit und Regulatorisches
GHS-Klassifizierung
GHS Classification
This chemical does not meet GHS hazard criteria for 11.1% (2 of 18) of reports.
Warning
H315 (77.8%): Causes skin irritation [Warning Skin corrosion/irritation]
P203, P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P318, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 18 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Regulatory Information
Chemical: 2,8-Phenazinediamine, N8,N8,3-trimethyl-, monohydrochloride
Phenazine, 3-amino-7-(dimethylamino)-2-methyl-, hydrochloride: Does not have an individual approval but may be used under an appropriate group standard
Sicherheitsdaten
- wgk
- 3
- tsca
- TSCA listed
- hs_code
- 32041300
- RTECS-Nr.
- SG1400000
- risk_code
- 68-36/37/38
- Toxizität
- LD50 intraperitoneal in mouse: 432mg/kg
- hazard_code
- Xn,Xi
- safety_code
- 36/37-37/39-36-26-24/25
- Speicherklasse
- 11 - Combustible Solids
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Substances used for the detection, identification, analysis, etc. of chemical, biological, or pathologic processes or conditions. Indicators are substances that change in physical appearance, e.g., color, at or approaching the endpoint of a chemical titration, e.g., on the passage between acidity and alkalinity. Reagents are substances used for the detection or determination of another substance by chemical or microscopical means, especially analysis. Types of reagents are precipitants, solvents, oxidizers, reducers, fluxes, and colorimetric reagents. (From Grant & Hackh's Chemical Dictionary, 5th ed, p301, p499)
Chemicals and substances that impart color including soluble dyes and insoluble pigments. They are used in INKS; PAINTS; and as INDICATORS AND REAGENTS.
Verwendung und Herstellung
Anwendungen
VerwendenNeutral Red is a common histology stain used to determine cell viability. It is also used as indicator for nitrogen determination; pH indicator; Dyes and metabolites.
Darstellung
synthetische(a) N,N-dimethyl-4-nitrosobenzenamineand 4-Methylbenzene-1,3-diaminereaction, form Toluylene Blue (Basic Dye, C.I. 49410), heating make cyclization; (b) oxidation N1,N1-dimethylbenzene-1,4-diamine, and 4-Methylbenzene-1,3-diamine mixture.
Vor- und nachgelagerte Produkte
Vorgelagerte Rohstoffe
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Ergänzende Hinweise
DefinitionChEBI: Neutral red is a hydrochloride obtained by combining the free base of neutral red with one equivalent of hydrochloric acid. Neutral red acts as a pH indicator, changing from red to yellow between pH 6.8 and 8.0. It has a role as a dye, an acid-base indicator and a two-colour indicator. It contains a neutral red(1+).
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