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Silberacetat
AgOAc · SILVER(I) ACETATE · silver acetate, anhydrous · ver acetate · Silver acetat · SILVER ACETATE · Acetoxysilver(I) · Silveracetate,99%
Identifikatoren & physikalische Daten
| CAS No. | 563-63-3 |
|---|---|
| Summenformel | AgC2H3O2 |
| Durchschnittliche Molmasse | 166,91 g/mol |
| Monoisotopische Masse | 165,91840134 g/mol |
| SMILES | CC(=O)[O-].[Ag+] |
| InChIKey | CQLFBEKRDQMJLZ-UHFFFAOYSA-M |
| PubChem CID | 11246 |
| ChEMBL | CHEMBL4464576 |
| EC No. | 209-254-9 |
| DTXSID | DTXSID8032041 |
| Lokaler Name | Silberacetat |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 40,1 |
|---|---|
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 5 |
| Formalladung | 0 |
| Komplexität | 25,5 |
| Stoffklassen | Metals -> Organic Acids, Metal Salts |
| Dichte | 3.26 at 68 °F (USCG, 1999) - Denser than waterwill sink3.25 |
| Physical Description | Silver acetate is a white crystalline plates. Light sensitive. Density 3.26 g / cm3.LiquidOther SolidWhite to slightly gray solidSoluble in 100 parts cold water[Merck Index] Solubility in water = 10 g/L[ChemIDplus] Beige powder[Aldrich MSDS] |
| Schmelzpunkt | decomposes [STR93] |
| Lagerbedingungen | Store below +30°C. |
| Löslichkeit | 10.2g/l10.2 g/L (20 ºC) |
| Aggregatzustand | Powder/Solid |
| Farbe | White to gray |
| Wichte | 3.259 |
| Merck | 14,8505 |
| BRN | 3595636 |
| Stabilität | Stable, but light sensitive. Incompatible with strong reducing agents. |
| InChI | 1S/C2H4O2.Ag/c1-2(3)4/h1H3,(H,3,4)/q+1/p-1 |
| InChIKey | CQLFBEKRDQMJLZ-UHFFFAOYSA-M |
| SMILES | CC(O[Ag])=O |
| CAS Datenbank | 563-63-3(CAS DataBase Reference) |
| NIST chemische Informationen | Silver acetate(563-63-3) |
| EPA chemische Informationen | Silver acetate (563-63-3) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P273, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 57 reports by companies from 14 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | Chemical: Acetic acid, silver(1+) saltAcetic acid, silver(1+) salt (1:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Acetic acid, silver(1+) salt (1:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Silver acetate: Does not have an individual approval but may be used under an appropriate group standard |
| Gesundheitsgefahren | Inhalation of dust irritates nose and throat. Contact with eyes or skin causes irritation. If continued for a long period, ingestion or inhalation of silver compounds can cause permanent discoloration of skin (argyria). (USCG, 1999) |
| Gefahrenübersicht | Sensitive to light[Merck Index] No evidence of developmental toxicity or teratogenicity in rats dosed by gavage on gestation days 6-19 (even at doses maternally toxic)NOAEL for maternal toxicity was 10 mg/kg/day and 100 mg/kg/day for developmental toxicity[NTP] Dust is irritating to eyes, nose, and throatSolid irritates skin and eyes[CHRIS] Caused effects to metabolism and plasma proteins in 4-day intermittent study of rats (641 mg/kg)[RTECS] A skin and strong eye irritantMay cause argyria[Aldrich MSDS] See Silver. |
| Reaktive Gruppe | Salts, Basic |
| Reactivity Profile | SILVER ACETATE is freely soluble in dilute nitric acid [Merck]. Can serve as an oxidizing agent. |
| Air and Water Reactions | Slightly soluble in water. |
| Hazard Classes and Categories | Skin Irrit. 2 (100%) |
| Erste Hilfe | INHALATION: move to fresh air. |
| Expositionsschutz und Persönliche Schutzausrüstung | 0.01 [mg/m3], inhalable fraction, as Ag (salts)[German Research Foundation (DFG)] |
| Threshold Limit Values (TLV) | 0.01 [mg/m3], as Ag (sol. compds.) |
| Permissible Exposure Limit (PEL) | 0.01 [mg/m3], as Ag (sol. compds.) |
| Personal Protective Equipment (PPE) | Dust maskgoggles or face shieldprotective gloves (USCG, 1999) |
| Immediately Dangerous to Life or Health (IDLH) | 10 mg Ag/m3 (NIOSH, 2024)10.0 [mg/m3], as Ag |
| Gesundheitliche Auswirkungen | Silver itself is not toxic to humans, but most silver salts are. In large doses, silver and compounds containing it can be absorbed into the circulatory system and become deposited in various body tissues, leading to argyria, which results in a blue-grayish pigmentation of the skin, eyes, and mucous membranes. Argyria is rare, and although, so far as known, this condition does not otherwise harm a person's health, it is disfiguring and usually permanent. Mild forms of argyria are sometimes mistaken for cyanosis. (L809) |
| Expositionspfade | Oral (L808)inhalation (L808)dermal (L808) |
| Toxizitätsübersicht | Metallic silver is oxidized and may deposit in the tissues, causing arygria. The silver ion is known to inhibit glutathione peroxidase and NA+,K+-ATPase activity, disrupting selenium-catalyzed sulfhydryl oxidation-reduction reactions and intracellular ion concentrations, respectively. Silver nanoparticles are believed to disrupt the mitochondrial respiratory chain, causing oxidative stress, reduced ATP synthesis, and DNA damage. (L808, A243, A244, A245, A246) |
| Signs and Symptoms | Exposure to high levels of silver for a long period of time may result in a condition called arygria, a blue-gray discoloration of the skin and other body tissues. Argyria is a permanent effect but does not appear to be harmful to health. Exposure to high levels of silver in the air has resulted in breathing problems, lung and throat irritation, and stomach pains. Skin contact with silver can cause mild allergic reactions such as rash, swelling, and inflammation in some people. (L808) |
| Carcinogen Classification | No indication of carcinogenicity to humans (not listed by IARC). |
| F | 8 |
| Wassergefährdungsklasse (WGK) | 3 |
| TSCA-Inventar-Status | TSCA listed |
| UN-Transportnummer | 1759 |
| Zollcode | 28432900 |
| RTECS-Nr. | AJ4100000 |
| R-Sätze (R) | 36/37/38-50 |
| Gefahrensymbole | Xi,N |
| Sicherheitshinweise (S) | 26-36-37/39-61 |
| Gefahrenklasse | 9Aquatic Acute 1Eye Irrit. 2Skin Irrit. 2STOT SE 3 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Beschreibung
Silver acetate is an organic compound with the empirical formula CH3COOAg (or AgC2H3O2). It is a photosensitive, white crystalline solid. It is a useful reagent in the laboratory as a water soluble source of silver lacking an oxidizing anion. It has been used in some antismoking drugs.
Verwenden
In the health field, silver acetate-containing products have been used in gum, spray, and lozenges to deter smokers from smoking. The silver in these products, when mixed with smoke, creates an unpleasant metallic taste in the smoker's mouth, thus deterring them from smoking. Lozenges containing 2.5 mg of silver acetate showed "modest efficacy" on 500 adult smokers tested over a three-month period. However, over a period of 12 months, prevention failed. In 1974, silver acetate was first introduced in Europe as an over-thecounter smoking-deterrent lozenge (Repaton) and then three years later as a chewing gum (Tabmint).