HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5-(4-fluorophenyl)-1-(4-(methylsulfonyl)phenyl)-3-(trifluoromethyl)-1H-Pyrazole
SC-58125 · SC-58125 ，E0789 · SC-58125, 10 mM in DMSO · 1-[(4-Methylsulfonyl)phenyl]-3-trifluoromethyl-5-(4-fluorophenyl)pyrazole · 5-(4-Fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-3-(trifluoromethyl)pyrazole · 5-(4-Fluoro-phenyl)-1-(4-methanesulfonyl-phenyl)-3-trifluoromethyl-1H-pyrazole · 5-(4-Fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazole · 1H-Pyrazole, 5-(4-fluorophenyl)-1-[4-(methylsulfonyl)phenyl]-3-(trifluoromethyl)-
Identifikatoren & physikalische Daten
| CAS No. | 162054-19-5 |
|---|---|
| Summenformel | C17H12F4N2O2S |
| Durchschnittliche Molmasse | 384,354 g/mol |
| Monoisotopische Masse | 384,0555615 g/mol |
| SMILES | CS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)cc2-c2ccc(F)cc2)cc1 |
| InChIKey | JHBIMJKLBUMNAU-UHFFFAOYSA-N |
| PubChem CID | 115239 |
| ChEMBL | CHEMBL274990 |
| ChEBI | CHEBI:8983 |
| EC No. | 664-277-5 |
| DTXSID | DTXSID00167304 |
Chemische & physikalische Eigenschaften
| Lagerbedingungen | Store at +4°C |
|---|---|
| Löslichkeit | DMSO: ≥20mg/mL |
| Aggregatzustand | powder |
| Farbe | white to off-white |
| InChI | 1S/C17H12F4N2O2S/c1-26(24,25)14-8-6-13(7-9-14)23-15(10-16(22-23)17(19,20)21)11-2-4-12(18)5-3-11/h2-10H,1H3 |
| InChIKey | JHBIMJKLBUMNAU-UHFFFAOYSA-N |
| SMILES | CS(=O)(=O)c1ccc(cc1)-n2nc(cc2-c3ccc(F)cc3)C(F)(F)F |
Sicherheit & Vorschriften
| Wassergefährdungsklasse (WGK) | 3 |
|---|---|
| R-Sätze (R) | 25 |
| Gefahrensymbole | T |
| Sicherheitshinweise (S) | 45-24/25-22 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
SC-58125 is a selective cyclooxygenase 2 (COX-2) inhibitor with anti-inflammatory properties. SC-58125 blocks edema and hyperalgesia without causing gastric mucosal damage. SC-58125 also displays anti tumor activity.