HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HCID 11640420Erstellt: 4. November 2026
2-[6-(4-Aminophenoxy)-3-oxo-3H-xanthen-9-yl]benzoic acid
APF · AMINOPHENYL FLUORESCEIN · 3-(p-Aminophenyl)fluorescein · 3-(p-Aminophenyl)fluorescein , APF · 2-[3-(4-aminophenoxy)-6-oxoxanthen-9-yl]benzoic acid · 2-[6-(4'-AMINO)PHENOXY-3H-XANTHEN-3-ON-9-YL]BENZOIC ACID · 2-[6-(4-AMINOPHENOXY)-3-OXO-3H-XANTHEN-9-YL]-BENZOIC ACID · 3'-(4-aminophenoxy)-6'-hydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one
https://huagongshe.com/de/chemical/11640420
Identifikatoren & physikalische Daten
| CAS No. | 359010-70-1 |
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| Summenformel | C26H17NO5 |
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| Durchschnittliche Molmasse | 423,4 g/mol |
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| Monoisotopische Masse | 423,11067264 g/mol |
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| SMILES | Nc1ccc(Oc2ccc3c(-c4ccccc4C(=O)O)c4ccc(=O)cc-4oc3c2)cc1 |
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| InChIKey | GIERQYKZWFLVGR-UHFFFAOYSA-N |
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| PubChem CID | 11640420 |
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| DTXSID | DTXSID40469879 |
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Chemische & physikalische Eigenschaften
| XLogP | 3,6 |
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| Polarare Oberfläche (TPSA) | 98,9 |
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| H-Brücken-Donoren | 2 |
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| H-Brücken-Akzeptoren | 6 |
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| Frei drehbare Bindungen | 4 |
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| Schwere Atome | 32 |
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| Formalladung | 0 |
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| Komplexität | 850 |
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| Endocrine Disruptors | Potential endocrine disrupting compound |
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| Siedepunkt | 677.7±55.0 °C(Predicted) |
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| Dichte | 1.52±0.1 g/cm3(Predicted) |
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| Lagerbedingungen | Store at -20°C |
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| Löslichkeit | DMF:20.0(Max Conc. mg/mL)47.23(Max Conc. mM)DMSO:10.0(Max Conc. mg/mL)23.62(Max Conc. mM)Ethanol:10.0(Max Conc. mg/mL)23.62(Max Conc. mM)Ethanol:PBS (pH 7.2) (1:3):0.5(Max Conc. mg/mL)1.18(Max Conc. mM) |
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| Aggregatzustand | Pale yellow liquid. |
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| pKa (Säurekonstante) | 9.61±0.20(Predicted) |
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| Farbe | Colorless to light yellow |
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Sicherheit & Vorschriften
| Alarmwort | Warnung |
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| Gefahrenhinweise | Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H302 |
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Anwendungen & Verwendung
Beschreibung
APF is an aromatic amino-fluorescein derivative and fluorescent probe for highly reactive radicals. It has low intrinsic fluorescence, however, upon oxidation by hydroxyl radical, hypochlorite ion, and certain peroxidase intermediates, it is converted to the highly fluorescent molecule fluorescein, facilitating the detection of highly reactive biological radicals. APF is not oxidized by nitric oxide (NO), hydrogen peroxide (H2O2), or other oxidants. Fluorescein displays excitation/emission maxima of 490/515 nm, respectively.
![Molekülstruktur von 2-[6-(4-Aminophenoxy)-3-oxo-3H-xanthen-9-yl]benzoic acid](/img/chemical/11640420.png)