Emamectin Benzoate
Grundinformationen
- CAS
137512-74-4- Standard-SMILES
CC[C@H](C)[C@H]1O[C@]2(C=C[C@@H]1C)C[C@@H]1C[C@@H](C/C=C(\C)[C@@H](O[C@H]3C[C@H](OC)[C@@H](O[C@H]4C[C@H](OC)[C@@H](NC)[C@H](C)O4)[C@H](C)O3)[C@@H](C)/C=C/C=C3\CO[C@@H]4[C@H](O)C(C)=C[C@@H](C(=O)O1)[C@]34O)O2.O=C(O)c1ccccc1- InChIKey
ISGYOHXFFCGHKT-LZTRAZQASA-N- Summenformel
- C56H81NO15
- Durchschnittliche Molmasse
- 1.008,2 g/mol
- Monoisotopische Masse
- 1.007,56062088
Überblick
Emamectin benzoate (Proclaim) is an avermectin class insecticide developed for the control of lepidopteron insects. This class of pesticide consists of homologous semi-synthetic macrolides that are derived from the natural fermentation products of Streptomyces bacteria. It kills insects by disrupting neurotransmitters, causing irreversible paralysis. It is more effective when ingested, but it also somewhat effective on contact. When sprayed to foliage, emamectin benzoate penetrates the leaf tissue and forms reservoir within treated leaves, which provides residual activity against pests that ingest the substance when feeding. Emamectin is widely used in the US and Canada as an insecticide because of its chloride channel activation properties. It is approved by the EPA for use in prevention of emerald ash borer in ash trees. Emamectin has also shown promising applications in the eradication of fish lice and in fish farming.
Namen und Bezeichner
- Bevorzugter Name
- Emamectin Benzoate
- IUPAC
- benzoic acid;(1'R,2R,3S,4'S,6S,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-2-[(2S)-butan-2-yl]-21',24'-dihydroxy-12'-[(2R,4S,5S,6S)-4-methoxy-5-[(2S,4S,5S,6S)-4-methoxy-6-methyl-5-(methylamino)oxan-2-yl]oxy-6-methyloxan-2-yl]oxy-3,11',13',22'-tetramethylspiro[2,3-dihydropyran-6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2'-one
- Englischer Name
- Emamectin benzoate
- Summenformel
- C49H77NO13
- Molmasse
- 888.13
Namen und Synonyme
Emamectin benzoate155569-91-8ProclaimDenimSliceShot-WanMethylamino abamectin benzoateEmamectin benzoate (salt)MK-244MK 244Avermectin b1, 4''-deoxy-4''-(methylamino)-, (4''R)-, benzoate (salt)4''-deoxy-4''-epi-N-methylaminoavermectin b1 benzoate
Weitere Namen anzeigen
Emamectine BenzoateEMaMectin Benzoate TechSch 58854Proclaim 5SGPROCLAIM(BANLEPTM)EMAMECTIN MIN.:90%EMAMECTIN MIN,:60%Avermectin Benzoate
HVM3G4A01WDTXSID0034566RefChem:590735CHEBI:39233SCH-58854(2S,3S,4S,6S)-6-(((2S,3S,4S,6R)-6-((1'R,2S,4'S,5S,6R,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-6-((2S)-butan-2-yl)-21',24'-dihydroxy-5,11',13',22'-tetramethyl-5,6-dihydro-3',7',19'-trioxaspiro(pyran-2,6'-tetracyclo(15.6.1.14,8.020,24)pentacosane)-10',14',16',22'-tetraen-2'-oneoxy)-4-methoxy-2-methyloxan-3-yl)oxy)-4-methoxy-N,2-dimethyloxan-3-aminium benzoateEmamectin B1 Benzoate137512-74-4
Eigenschaften
Berechnete Struktureigenschaften
- Polarare Oberfläche (TPSA)
- 199 Ų
- H-Brücken-Donoren
- 4
- H-Brücken-Akzeptoren
- 16
- Frei drehbare Bindungen
- 10
- Schwere Atome
- 72
- Formalladung
- 0
- Komplexität
- 1.850
Experimentelle und physikochemische Eigenschaften
PesticidesPesticide (Emamectin benzoate) -> USDA PDB
Physikochemische Eigenschaften
- Schmelzpunkt
- 146 · 146-150°C
- Dampfdruck
- 4 x · 4 x 10-7mPa
- storage temp.
- Refrigerator
- Löslichkeit
- Chloroform (Slightly), Methanol (Slightly)
- Aggregatzustand
- Solid
- pka
- 4.2 · 4.2; 7.6(at 25℃)
- Wasserlöslichkeit
- 320 mg · 320 mg l-1 (pH 5), 24 mg l-1 (pH 7), 0.1 mg l-1 (pH 9)
- Farbe
- Pale Yellow to Light Yellow
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Danger
H301: Toxic if swallowed [Danger Acute toxicity, oral]
P260, P261, P262, P264, P264+P265, P270, P271, P273, P280, P301+P316, P302+P352, P304+P340, P305+P354+P338, P308+P316, P316, P317, P319, P321, P330, P361+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)
This chemical does not meet GHS hazard criteria for 1% (1 of 105) of reports.
Danger
H301+H311+H331 (98.1%): Toxic if swallowed, in contact with skin or if inhaled [Danger Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]
Gefahrenhinweise
Regulatory Information
Emamectin Benzoate is listed in the dataset of EPA Human Health Benchmarks for Pesticides under the Safe Drinking Water Act (40 eCFR 141)
Emamectin benzoate: Does not have an individual approval but may be used as a component in a product covered by a group standard. It is not approved for use as a chemical in its own right.
Hazard Classes and Categories
Acute Tox. 3 (99%)
Acute toxicity (Oral) - Category 3
Acute toxicity (Dermal) - Category 3
Acute Tox. 3
Toxikologische Informationen
Carcinogen ClassificationNo indication of carcinogenicity to humans (not listed by IARC).
RAIS Toxicity Values
0.0025
OPP
0.0025
OPP
EPA Human Health Benchmarks for Pesticides
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Drugs used to treat or prevent parasitic infections.
Pesticides designed to control insects that are harmful to man. The insects may be directly harmful, as those acting as disease vectors, or indirectly harmful, as destroyers of crops, food products, or textile fabrics.
Verwendung und Herstellung
UsesThis is a man-made compound that is used as a pesticide.
Use ClassificationVeterinary Drug -> VETERINARY_DRUG -> JECFA Functional Classes
Anwendungen
VerwendenEmamectin benzoate is a second-generation avermectin insecticide highly effective against a broad range of lepidopteran larvae and certain other insects.
Vor- und nachgelagerte Produkte
Vorgelagerte Rohstoffe
Anbieter
Wird geladen…
Öffentliche Anfragen
Wird geladen…
Zugehörige Reaktionen
0
Keine Reaktionsaufzeichnungen unter den aktuellen Filterkriterien.
Notizen zur Verbindung
Wird geladen…