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HCID 11763533Erstellt: 26. Oktober 2026
(1,3-Bis(2,4,6-trimethylphenyl)imidazolidin-2-ylidene)(dichloro)((2-((propan-2-yl)oxy)phenyl)methylidene)ruthenium
HOVEYDA-GRUBBS · HOVEYDA-GRUBBS CATALYST · Hoveyda-Grubbs II · Hoveyda-Grubbs 2nd · Hoveyda-Grubbs Catalyst 2nd · Hoveyda-Grubbs Catalyst 2nd Generation · Hoveyda-Grubbs G2 · Dichloro(1,3-diMesityl-2-iMidazolidinylidene)(2-isopropoxybenzylidene)rutheniuM
https://huagongshe.com/de/chemical/11763533
Identifikatoren & physikalische Daten
| CAS No. | 301224-40-8 |
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| Summenformel | C31H38Cl2N2ORu |
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| Durchschnittliche Molmasse | 626,6 g/mol |
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| Monoisotopische Masse | 626,1404685 g/mol |
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| SMILES | Cc1cc(C)c(N2CCN(c3c(C)cc(C)cc3C)[C]2=[Ru]([Cl])([Cl])=[CH]c2ccccc2OC(C)C)c(C)c1 |
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| InChIKey | ZRPFJAPZDXQHSM-UHFFFAOYSA-L |
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| PubChem CID | 11763533 |
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| DTXSID | DTXSID90471982 |
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Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 15,7 |
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| H-Brücken-Donoren | 0 |
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| H-Brücken-Akzeptoren | 3 |
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| Frei drehbare Bindungen | 5 |
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| Schwere Atome | 37 |
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| Formalladung | 0 |
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| Komplexität | 828 |
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| Schmelzpunkt | 216-220 °C(lit.) |
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| Lagerbedingungen | 2-8°C |
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| Löslichkeit | Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly) |
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| Aggregatzustand | Solid |
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| Farbe | Green to Very Dark Green |
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| Stabilität | Hygroscopic |
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| InChIKey | ZRPFJAPZDXQHSM-UHFFFAOYSA-L |
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| SMILES | [Cl-][Ru+6]1(=[C-2]2N(C3C(=CC(C)=CC=3C)C)CCN2C2C(=CC(C)=CC=2C)C)(=[C-2]C2=CC=CC=C2O1C(C)C)[Cl-] |
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| CAS Datenbank | 301224-40-8 |
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| EPA chemische Informationen | Ruthenium, [1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene]dichloro[[2-(1-methylethoxy-.kappa.O)phenyl]methylene-.kappa.C]-, (SP-5-41)- (301224-40-8) |
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Sicherheit & Vorschriften
| Wassergefährdungsklasse (WGK) | 3 |
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| TSCA-Inventar-Status | TSCA listed |
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| Lagerklasse | 11 - Combustible Solids |
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Anwendungen & Verwendung
Verwenden
It′s a phosphine free version of Grubbs 2nd Generation Catalyst with comparable reactivity, but initiates more readily at lower temperatures. Efficient for metathesis of electron-deficient substrates including fluorinated olefins. Demonstrated in multiple large-scale pharmaceutical applications.It can be used as a catalyst for olefin cross-metathesis with fluorinated olefins (CM), ring-closing metathesis (RCM), ring-opening metathesis (ROM), and a sequence of a metathesis reaction and subsequent dihydroxylation of the newly formed double bond.
