2-Amino-2-methylpropanol
2-Amino-2-methyl-1-propanol
Grundinformationen
- CAS
124-68-5- Standard-SMILES
CC(C)(N)CO- InChIKey
CBTVGIZVANVGBH-UHFFFAOYSA-N- Summenformel
- C4H11NO
- Durchschnittliche Molmasse
- 89,14 g/mol
- Monoisotopische Masse
- 89,08406397
Überblick
2-amino-2-methyl-1-propanol appears as a clear light colored liquid. Insoluble in water and about the same density as water. Flash point 172 °F. Used to make other chemicals.
Namen und Bezeichner
- Bevorzugter Name
- 2-Amino-2-methyl-1-propanol
- IUPAC
- 2-amino-2-methylpropan-1-ol
- Lokaler Name
- 2-Amino-2-methylpropanol
- Englischer Name
- 2-Amino-2-methyl-1-propanol
- Summenformel
- C4H11NO
- Molmasse
- 89.14
Namen und Synonyme
2-Amino-2-methyl-1-propanol124-68-52-AminoisobutanolAminomethylpropanolIsobutanol-2-amineAMP Regular1-Propanol, 2-amino-2-methyl-2-AminodimethylethanolAmp-952-AMINO-2-METHYLPROPANOL2-Methyl-2-aminopropanolCorrguard 75
Weitere Namen anzeigen
2-AMINO-2-METHYLPROPAN-1-OLKarl Fischer2-methyl-2-amino-1-propanolmonoisobutanolamine2,2-Diethyl-ethanolamine2-amino-2-methyl-1-propano
Hydroxy-tert-butylamineAMP (thinner)2-Amino-2,2-dimethylethanolIsobutanolamine1,1-Dimethyl-2-hydroxyethylamine2-Hydroxymethyl-2-propylamine2-Methyl-2-aminopropanol-12-Amino-1-hydroxy-2-methylpropane
Datenbank-Bezeichner
- CAS
124-68-5- PubChem CID
- 11807
- DTXSID
DTXSID8027032- ChEMBL
CHEMBL122588
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- -0,8
- Polarare Oberfläche (TPSA)
- 46,3 Ų
- H-Brücken-Donoren
- 2
- H-Brücken-Akzeptoren
- 2
- Frei drehbare Bindungen
- 1
- Schwere Atome
- 6
- Formalladung
- 0
- Komplexität
- 42,8
Experimentelle und physikochemische Eigenschaften
Chemical Classes
Nitrogen Compounds -> Amines, Aliphatic
Flammable agents - 2nd degree
Cosmetics
Cosmetic ingredients (Aminomethyl Propanol) -> CIR (Cosmetic Ingredient Review)
Cosmetic ingredients (Aminomethylpropanol) -> CIR (Cosmetic Ingredient Review)
Buffering
pHPH OF 0.1 AQ SOLN 11.3
SpringerMaterials PropertiesChemical diffusion
Density
0.935 (USCG, 1999) - Less dense than water; will float
0.934 @ 20 °C/20 °C
0.93 g/cm³
0.935
0.934 @25 °C
Color/FormCRYSTALLINE MASS
Solubility
MISCIBLE WITH WATER; SOL IN ALCOHOLS
Solubility in water: miscible
Flash Point
153 °F (USCG, 1999)
67 °C
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Warning
H315: Causes skin irritation [Warning Skin corrosion/irritation]
P264, P264+P265, P273, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, P362+P364, and P501 (click each P-code to see the statement)
This chemical does not meet GHS hazard criteria for 0.3% (12 of 4294) of reports.
Warning
H315 (99.7%): Causes skin irritation [Warning Skin corrosion/irritation]
Gefahrenhinweise
Regulatory Information
Chemical: 1-Propanol, 2-amino-2-methyl-
1-Propanol, 2-amino-2-methyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1-Propanol, 2-amino-2-methyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
REACH registered substance: 2-amino-2-methylpropanol (EC: 204-709-8)
2-Amino-2-methyl-1-propanol: Does not have an individual approval but may be used under an appropriate group standard
The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)
Other Safety InformationIMAP assessments - 1-Propanol, 2-amino-2-methyl-: Environment tier I assessment
DOT LabelCombustible Liquid
Fire Hazards
Special Hazards of Combustion Products: Emits toxic fumes during fire conditions. (USCG, 1999)
Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Above 67 °C explosive vapour/air mixtures may be formed.
Chemie und Industrie
Pharmakologische Informationen
Absorption, Distribution and Excretion
METABOLISM AND DISTRIBUTION OF (3)H-LABELED 2-AMINO-2-METHYLPROPANOL WAS STUDIED IN RATS RECEIVING NORMAL OR CHOLINE-DEFICIENT DIETS. TRITIUM APPEARED IN THE SERUM OF BOTH GROUPS 30 MIN AFTER THE IP INJECTION BUT THE LEVEL WAS GENERALLY LOWER IN THE CHOLINE-DEFICIENT GROUP. RATS ON THE NORMAL DIET EXCRETED MORE OF THE AMINO ACID IN THE URINE THAN DID THE CHOLINE-DEFICIENT RATS IN BOTH GROUPS ONLY THE UNCHANGED AMINO ACID WAS EXCRETED. LIVERS FROM THE CHOLINE-DEFICIENT GROUP HAD A GREATER UPTAKE AND RETENTION OF THE LABEL THAN THOSE FROM NORMAL RATS. MOST OF THE LABEL WAS FOUND IN THE CYTOSOL OF BOTH LIVER AND KIDNEY.
Verwendung und Herstellung
Uses
CIR ingredient: Aminomethyl Propanol
CIR ingredient: Aminomethylpropanol
Used to make other chemicals (surface-active agents, vulcanization accelerators, and pharmaceuticals) and as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, leather dressings, textile specialties, polishes, cleaning compounds, and so-called soluble oils; Also used in hair sprays, wave sets, hair dyes, Pamabrom (drug), and absorbents for acidic gases; [Merck Index] Used as a pigment dispersant for water-based paints, resin solubilizer, corrosion inhibitor, protecting agent for carbonyl groups and in boiler-water treatment; [CHEMINFO]
Painting (Pigments, Binders, and Biocides) [Category: Paint]
IN SYNTH OF SURFACE-ACTIVE AGENTS, VULCANIZATION ACCELERATORS, PHARMACEUTICALS; ABSORBENT FOR ACIDIC GASES; EMULSIFYING AGENT FOR COSMETIC CREAMS AND LOTIONS, MINERAL OIL & PARAFFIN WAX EMULSIONS, LEATHER DRESSINGS, TEXTILE SPECIALTIES, POLISHES, CLEANING COMPOUNDS, SO-CALLED SOL OILS; INGREDIENT OF DIURETIC PAMABROM
U.S. Production2023: 10,000,000 - <50,000,000 lb
Consumer UsesNot Known or Reasonably Ascertainable
Industry UsesPigment
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