HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
7-Methylchinolin
Quinoline, 7-methyl- · m-Toluquinoline · 7-methyquinoline · 7-Methylchinolin · 7-methyl-quinolin · 7-METHYLQUINOLINE · 7-Methylquinolinol · 7-Methylquiuoline
Identifikatoren & physikalische Daten
| CAS No. | 612-60-2 |
|---|---|
| Summenformel | C10H9N |
| Durchschnittliche Molmasse | 143,18 g/mol |
| Monoisotopische Masse | 143,07349929 g/mol |
| SMILES | Cc1ccc2cccnc2c1 |
| InChIKey | KDYVCOSVYOSHOL-UHFFFAOYSA-N |
| PubChem CID | 11927 |
| ChEMBL | CHEMBL1322524 |
| EC No. | 210-316-2 |
| DTXSID | DTXSID5025657 |
| Lokaler Name | 7-Methylchinolin |
Chemische & physikalische Eigenschaften
| XLogP | 2,5 |
|---|---|
| Polarare Oberfläche (TPSA) | 12,9 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 1 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 11 |
| Formalladung | 0 |
| Komplexität | 133 |
| Stoffklassen | Nitrogen Compounds -> Quinolines |
| SpringerMaterials Properties | Boiling point |
| LogP (Verteilungskoeffizient) | 2.47 |
| Dichte | 1.0609 at 68 °F (NTP, 1992) - Denser than waterwill sink1.061 |
| Löslichkeit | less than 1 mg/mL at 68 °F (NTP, 1992)Chloroform (Slightly), Methanol (Slightly)<0.1 g/100 mL at 20 ºC |
| Flammpunkt | 230 °F (NTP, 1992)>230 °F |
| Siedepunkt | 484.7 to 486.5 °F at 760 mmHg (NTP, 1992)258 °C(lit.) |
| Schmelzpunkt | 95 to 100 °F (NTP, 1992)35-37 °C(lit.) |
| Physical Description | 7-methylquinoline appears as clear yellow liquid or oil. (NTP, 1992)Clear yellow liquidmp = 35-38 deg C[CAMEO] Viscous liquid[Alfa Aesar MSDS] |
| Brechungsindex | 1.6070 to 1.6210 |
| Lagerbedingungen | Room Temperature |
| pKa (Säurekonstante) | 5.44±0.14(Predicted) |
| Aggregatzustand | Viscous Liquid |
| Farbe | Off-White to Pale Beige Low-Melting |
| BRN | 110317 |
| Stabilität | Stable. Incompatible with strong oxidizing agents, strong acids. May be light sensitive. |
| InChI | 1S/C10H9N/c1-8-4-5-9-3-2-6-11-10(9)7-8/h2-7H,1H3 |
| InChIKey | KDYVCOSVYOSHOL-UHFFFAOYSA-N |
| SMILES | Cc1ccc2cccnc2c1 |
| CAS Datenbank | 612-60-2(CAS DataBase Reference) |
| NIST chemische Informationen | Quinoline, 7-methyl-(612-60-2) |
| EPA chemische Informationen | 7-Methylquinoline (612-60-2) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 45 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| DOT-Kennzeichnung | Corrosive |
| Brandgefahren | This chemical is combustible. (NTP, 1992) |
| Gesundheitsgefahren | SYMPTOMS: This compound may be absorbed through the skin and it causes skin irritation. The vapor or mist is irritating to the eyes, mucous membranes and upper respiratory tract. |
| Gefahrenübersicht | A skin irritantVapor or mist causes eye, mucous membranes, and upper respiratory tract irritationMay be absorbed through skin[NTP] An irritantRisk of irreversible adverse health effects[Alfa Aesar MSDS] See Quinoline. |
| Reaktive Gruppe | Amides and Imides |
| Reactivity Profile | 7-METHYLQUINOLINE may be sensitive to exposure to light. May react vigorously with strong oxidizing agents and strong acids (NTP, 1992). Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides. |
| Air and Water Reactions | Insoluble in water. |
| Hazard Classes and Categories | Skin Irrit. 2 (100%) |
| Brandbekämpfung | Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992) |
| Erste Hilfe | EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. |
Anwendungen & Verwendung
Verwenden
7-methylquinoline has been bioassayed as tumor initiator on the skin of Sencar mice.