(3β,5β,11α)-3-[(2,6-Dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)oxy]-11,14-dihydroxycard-20(22)-enolide

BeschreibungDivasidum is a cardiac glycoside compound found in the seeds of Apocynaceae plant Strophanthus divaricatus. Strophanthus divaricatus is also known as Gelsemium elegans and Morinda umbellata L. This plant was recorded in Flora of China . “Bencaoqiuyuan” suggested that it can be used for treating itching and tinea capitis. “Lu Chuan Materia Medica” and “Lingnan herbal medicine” also suggest that it is useful for treating sore, congestion, malignant ulcers, and bruises. It grows in Guizhou, Yunnan, Guangxi, Guangdong, and Fujian provinces in China. It is also distributed in Vietnam and Laos. Divasidum, decogenin, sarmentogenin, sarmutogenin, bipindogenin, and other types of cardiac glycosides are found in the roots, stems, leaves, and other parts of Strophanthus divaricatus. In China, divasidum has been developed into injection for the treatment of heart failure.

HistoryA white amorphous saponin was first extracted from the seeds of Strophanthus divari_x005fcatus in 1940, and the content is 1.8%. Strophanthiline A, B, and C were then identified. Its effect is about two-thirds of that of strophanthin K.Then, divaricoside (content 0.46%) and caudoside (content 0.19%) were identified in 1953 and 1954 .