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Formylhydrazin
FORMOHYDRAZIDE · FORMIC HYDRAZIDE · FORMIC ACID HYDRAZIDE · Formic hydrazine · hydrazinecarboxaldehyde · Formhydrazide · Formylhydrazide · Formhydrazid
Identifikatoren & physikalische Daten
| CAS No. | 624-84-0 |
|---|---|
| Summenformel | CH4N2O |
| Durchschnittliche Molmasse | 60,056 g/mol |
| Monoisotopische Masse | 60,03236276 g/mol |
| SMILES | NNC=O |
| InChIKey | XZBIXDPGRMLSTC-UHFFFAOYSA-N |
| PubChem CID | 12229 |
| EC No. | 210-867-9 |
| DTXSID | DTXSID6020642 |
| Lokaler Name | Formylhydrazin |
Chemische & physikalische Eigenschaften
| XLogP | -2 |
|---|---|
| Polarare Oberfläche (TPSA) | 55,1 |
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 2 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 4 |
| Formalladung | 0 |
| Komplexität | 20 |
| Schmelzpunkt | 52-57 °C (lit.) |
| Siedepunkt | 90°C/0.7mmHg(lit.) |
| Dichte | 1.094±0.06 g/cm3(Predicted) |
| Brechungsindex | 1.4840 (estimate) |
| Flammpunkt | >230 °F |
| Lagerbedingungen | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C |
| Löslichkeit | water: soluble2.5%, clear, colorless |
| pKa (Säurekonstante) | 13.65±0.20(Predicted) |
| Aggregatzustand | Shiny Crystalline Flakes |
| Farbe | White |
| BRN | 635759 |
| InChI | 1S/CH4N2O/c2-3-1-4/h1H,2H2,(H,3,4) |
| InChIKey | XZBIXDPGRMLSTC-UHFFFAOYSA-N |
| SMILES | [H]C(=O)NN |
| CAS Datenbank | 624-84-0(CAS DataBase Reference) |
| NIST chemische Informationen | Formic acid hydrazide(624-84-0) |
| EPA chemische Informationen | Hydrazinecarboxaldehyde (624-84-0) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]H335 (62%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposureRespiratory tract irritation]H336 (35.4%): May cause drowsiness or dizziness [Warning Specific target organ toxicity, single exposureNarcotic effects]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 79 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website. |
|---|---|
| Hazard Classes and Categories | Skin Irrit. 2 (100%)Eye Irrit. 2 (100%)STOT SE 3 (62%)STOT SE 3 (35.4%) |
| F | 3-8-10 |
| Wassergefährdungsklasse (WGK) | 3 |
| TSCA-Inventar-Status | TSCA listed |
| Zollcode | 29280000 |
| RTECS-Nr. | LQ8615000 |
| R-Sätze (R) | 36/37/38-20/21/22 |
| Gefahrensymbole | Xi,Xn |
| Sicherheitshinweise (S) | 26-36-36/37/39 |
| Lagerklasse | 11 - Combustible Solids |
| Gefahrenklasse | Eye Irrit. 2Skin Irrit. 2STOT SE 3 |
Anwendungen & Verwendung
Verwenden
Formic acid hydrazide is used as a precursor in the preparation of 1,2,4-triazole derivatives. It is also used in the synthesis of 6-N-formylamino-12,13-dihydro-1,11-dihydroxy-13-(beta-D-glucopyranosyl)-5H-indolo[2,3-a]-pyrrolo[3,4-c]carbazole-5,7(6H)-dione, which is an anticancer agent.