Ethyl 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate

HCID 1268243CAS 100491-29-0
TeilstruktursucheÄhnliche Strukturen suchen

Grundinformationen

Standard-SMILES
CCOC(=O)c1cn(-c2ccc(F)cc2F)c2nc(Cl)c(F)cc2c1=O
InChIKey
JLSXYCZRMYCIMY-UHFFFAOYSA-N
Summenformel
C17H10ClF3N2O3
Durchschnittliche Molmasse
382,7 g/mol
Monoisotopische Masse
382,03320452

Namen und Bezeichner

Bevorzugter Name
Ethyl 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate
IUPAC
ethyl 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylate
Englischer Name
ETHYL 1-(2,4-DIFLUOROPHENYL)-7-CHORO-6-FLUORO-4-OXO-HYDROPYRIDINO[2,3-B] PYRIDINE-3-CARBOXYLATE
Summenformel
C17H10ClF3N2O3
Molmasse
382.72

Namen und Synonyme

100491-29-0EC 422-360-1ethyl 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylateRefChem:596007422-360-1ethyl 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylateethyl 7-chloro-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylateMFCD018632857-Chloro-6-fluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid Ethyl EsterETHYL 1-(2,4-DIFLUOROPHENYL)-7-CHORO-6-FLUORO-4-OXO-HYDROPYRIDINO[2,3-B] PYRIDINE-3-CARBOXYLATEST0671131,8-Naphthyridine-3-carboxylic acid,7-chloro-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-, ethyl ester
Weitere Namen anzeigen
ETHYL 1-(2RRR-α-TocopherolumTosufloxacin ImpurityTosufloxacin Impurity 23-B] PYRIDINE-3-CARBOXYLATEEthyl 7-chloro-1-(2,4-difluorophenyl)4-DIFLUOROPHENYL)-7-CHORO-6-FLUORO-4-OXO-HYDROPYRIDINO[2-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylateETHYL 1-(2,4-DIFLUOROPHENYL)-7-CHORO-6-FLUORO-4-OXO-HYDROPYR...ethyl1-(2,4-difluorophenyl)-7-chloro-6-fluoro-4-oxohydropyridino
7-Chloro-6-fluoro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid Ethylethyl 1-(2,4-difluorophenyl)-7-chloro-6-fluoro-4-oxohydropyridino[2,3-b]pyridi ne-3-carboxylateETHYL 7-CHLORO-1-(2,4-DIFLUOROPHENYL)-6-FLUORO-4-OXO-1,4-DIHYDRO[1,8]NAPHTHYRIDINE-3-CARBOXYLATEC17H10ClF3N2O37-Chloro-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid Ethyl Ester; Ethyl 1-(2,4-Difluorophenyl)-7-chloro-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate;AMY155457-ChlorOprea1_565735

Datenbank-Bezeichner

CAS
100491-29-0
PubChem CID
1268243
DTXSID
DTXSID30361479
EC Number
422-360-1、600-101-5
Nikkaji
J385.981I

Eigenschaften

Berechnete Struktureigenschaften

XLogP
4
Polarare Oberfläche (TPSA)
59,5 Ų
H-Brücken-Donoren
0
H-Brücken-Akzeptoren
8
Frei drehbare Bindungen
4
Schwere Atome
26

Physikochemische Eigenschaften

Schmelzpunkt
212 · 212-215 °C
Siedepunkt
502.5 · 502.5±50.0 °C(Predicted)
Dichte
1.4752 · 1.4752 (estimate)
storage temp.
2 · under inert gas (nitrogen or Argon) at 2-8°C
Löslichkeit
DMSO (Slightly, Heated), Methanol (Very Slightly, Heated)
Aggregatzustand
Solid

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

Warning

H317: May cause an allergic skin reaction [Warning Sensitization, Skin]

P261, P272, P273, P280, P302+P352, P321, P333+P317, P362+P364, P391, and P501 (click each P-code to see the statement)

Warning

H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]

P261, P272, P273, P280, P302+P352, P321, P333+P317, P362+P364, P391, and P501 (click each P-code to see the statement)

Gefahrenhinweise

Regulatory InformationStatus: Active Update: 15-12-2008 https://echa.europa.eu/registration-dossier/-/registered-dossier/9206
Hazard Classes and Categories · 3 Einträge

Skin Sens. 1 (100%)

Skin sensitisation - category 1

Skin Sens. 1

Sicherheitsdaten

hs_code
29339980
risk_code
36/37/38
hazard_code
Xi
safety_code
37/39-26

Chemie und Industrie

Anwendungen

VerwendenAn intermediate of Trovafloxacin (T893000) and analogs.

Vor- und nachgelagerte Produkte

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毕佳索（上海毕得医药科技股份有限公司）400-6005915 · [email protected]
上海炎泽化工有限公司15345144255 19975051755 · [email protected]
温州共赢化学有限公司+86-0086-577-64498589 +86-15355981851 · [email protected]
清宁生物（江苏博泉生物科技有限公司）19352250998 · [email protected]
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