Foslevodopa
Grundinformationen
- CAS
101141-95-1- Standard-SMILES
N[C@@H](Cc1ccc(OP(=O)(O)O)c(O)c1)C(=O)O- InChIKey
YNDMEEULGSTYJT-LURJTMIESA-N- Summenformel
- C9H12NO7P
- Durchschnittliche Molmasse
- 277,17 g/mol
- Monoisotopische Masse
- 277,03513835
Überblick
Foslevodopa is an L-tyrosine derivative that is L-dopa in which the hydroxy group at position 4' is replaced by a phosphonooxy group. It is a water-soluble prodrug of levodopa which is used for the treatment of Parkinson's disease. It has a role as an antiparkinson drug and a prodrug. It is an O-phosphoamino acid, a L-tyrosine derivative and a non-proteinogenic L-alpha-amino acid. It is functionally related to a L-dopa.
Namen und Bezeichner
- Bevorzugter Name
- Foslevodopa
- IUPAC
- (2S)-2-amino-3-(3-hydroxy-4-phosphonooxyphenyl)propanoic acid
- Englischer Name
- DOPA 4-phosphate
- Summenformel
- C9H12NO7P
- Molmasse
- 277.167841
Namen und Synonyme
Foslevodopa97321-87-4Levodopa-4'-monophosphate3-hydroxy-O-phosphono-L-tyrosineFoslevodopa [USAN](2S)-2-amino-3-(3-hydroxy-4-phosphonooxyphenyl)propanoic acid37NQZ0J76IFOSLEVODOPA [INN]FOSLEVODOPA [JAN]ABBV-951 COMPONENT FOSLEVODOPAL-TYROSINE, 3-HYDROXY-O-PHOSPHONO-L-TYROSINE, 3-HYDROXY-, 4-(DIHYDROGEN PHOSPHATE)
Weitere Namen anzeigen
DOPA 4-PHOSPHONATE
foslevodopumRefChem:600352Dopa 4-phosphateABBV-951101141-95-1UNII-37NQZ0J76IWHO 11006(S)-2-amino-3-(3-hydroxy-4-(phosphonooxy)phenyl)propanoic acid
Datenbank-Bezeichner
- CAS
101141-95-1、97321-87-4- PubChem CID
- 127766
- DTXSID
DTXSID70905957- ChEMBL
CHEMBL4594379- ChEBI
CHEBI:192509- UNII
- 37NQZ0J76I
- Nikkaji
- J3.795.603A
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- -4
- Polarare Oberfläche (TPSA)
- 150 Ų
- H-Brücken-Donoren
- 5
- H-Brücken-Akzeptoren
- 8
- Frei drehbare Bindungen
- 5
- Schwere Atome
- 18
- Formalladung
- 0
- Komplexität
- 344
Experimentelle und physikochemische Eigenschaften
Human Drugs
FDA approved drugs -> Active ingredient
FDA approved drugs -> Active ingredient
Chemie und Industrie
Anbieter12 Anbieter
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