Fluoroclebopride
Daten werden ergänzt – lade die Seite später neu, um den aktuellen Stand zu sehen
Grundinformationen
- CAS
154540-49-5- Standard-SMILES
COc1cc(N)c(Cl)cc1C(=O)NC1CCN(Cc2ccc(F)cc2)CC1- InChIKey
HKDIGEWWDHALIS-UHFFFAOYSA-N- Summenformel
- C20H23ClFN3O2
- Durchschnittliche Molmasse
- 391,874 g/mol
- Monoisotopische Masse
- 391,14628288
Namen und Bezeichner
- Bevorzugter Name
- Fluoroclebopride
- IUPAC
- 4-Amino-5-chloro-N-{1-[(4-fluorophenyl)methyl]piperidin-4-yl}-2-methoxybenzamide
- Englischer Name
- 4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamide
- Summenformel
- C20H23ClFN3O2
- Molmasse
- 391.87
Namen und Synonyme
fluorocleboprideFluoroclebopride, 10 mM in DMSOAbmole M4962-10mg fluoroclebopride 154540-49-5Abmole M4962-50mg fluoroclebopride 154540-49-5Inhibitor,inhibit,Fluoroclebopride,Dopamine Receptor4-Amino-5-chloro-N-(1-((4-fluorophenyl)methyl)-4-piperidinyl)-2-methox ybenzamideBenzamide,4-amino-5-chloro-N-[1-[(4-fluorophenyl)methyl]-4-piperidinyl]-2-methoxy-
Datenbank-Bezeichner
- CAS
154540-49-5- PubChem CID
- 127887
- DTXSID
DTXSID10165659- ChEMBL
CHEMBL125237- Nikkaji
- J578.038A
Eigenschaften
Physikochemische Eigenschaften
- Siedepunkt
- 518.2 · 518.2±50.0 °C(Predicted)
- Dichte
- 1.31 · 1.31±0.1 g/cm3(Predicted)
- storage temp.
- -20 °C · Store at -20°C
- Löslichkeit
- 20 mg/ml; · DMF: 20 mg/ml; DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml
- Aggregatzustand
- A crystalline solid
- pka
- 13.62 · 13.62±0.20(Predicted)
- Farbe
- White to off-white
Chemie und Industrie
Anwendungen
BeschreibungFluoroclebopride is a benzamide analog that is used in positron emission tomography (PET) applications. It binds reversibly to dopamine receptors (Kis = 0.95, 5.7, 5.46, and 144 nM for D2-like, D2(long), D3, and D4 receptors, respectively, in radioligand binding assays). It is selective for these receptors over D1, serotonin 5-HT2, and α2-adrenergic receptors (Kis = >10,000, 283, and 1,300 nM, respectively). A fluorine-18 moiety has been used to label this compound for use as a probe for studying D2/D3 receptor availability via PET in various monkey models.
Anbieter37 Anbieter
成都超九八生物科技有限公司13348960310 13348960310 · [email protected]
湖北科乐精细化工有限公司027-59101668 19945030958 · [email protected]
Aladdin Scientific[email protected]
上海波以尔化工有限公司[email protected]
InvivoChem中国13549236410 · [email protected]
学研惠（武汉）科技有限公司15727060112 · [email protected]
上海尺水药物研究有限公司[email protected] 13564957716 · [email protected]
Zhejiang J&C Biological Technology Co.,Limited+1-2135480471 · [email protected]
上海泽涵生物医药科技有限公司021-61350663 13052117465 · [email protected]
上海东苍生物科技有限公司+86-21-58447131 · [email protected]
Zugehörige Reaktionen
0
Keine Reaktionsaufzeichnungen unter den aktuellen Filterkriterien.
Notizen zur Verbindung
Wird geladen…