HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
9-Dechloro-11-oxo mometasone furoate
Mometasone Impurity C · Mometasone ImpurityEP-C · Mometasone EP Impurity C · Mometasone Furoate EP Impurity C · Mometasone Furoate Impurity 3(Mometasone Furoate EP Impurity C) · 21-Chloro-16α-methyl-3,11,20-trioxopregna-1,4-dien-17-yl furan-2-carboxylate · Mometasone Furoate EP Impurity C (Mometasone Furoate USP Related Compound C) · (16α)-21-Chloro-17-[(2-furanylcarbonyl)oxy]-16-methylpregna-1,4-diene-3,11,20-trione
Identifikatoren & physikalische Daten
| CAS No. | 1305334-31-9 |
|---|---|
| Summenformel | C27H29ClO6 |
| Durchschnittliche Molmasse | 485 g/mol |
| Monoisotopische Masse | 484,1652663 g/mol |
| SMILES | C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3C(=O)C[C@]2(C)[C@@]1(OC(=O)c1ccco1)C(=O)CCl |
| InChIKey | UDJQOKVZFMMKGS-GJMULMBRNA-N |
| PubChem CID | 129011920 |
Chemische & physikalische Eigenschaften
| XLogP | 3,9 |
|---|---|
| Polarare Oberfläche (TPSA) | 90,7 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 6 |
| Frei drehbare Bindungen | 5 |
| Schwere Atome | 34 |
| Formalladung | 0 |
| Komplexität | 1.010 |
| Schmelzpunkt | >123°C (dec.) |
| Siedepunkt | 631.6±55.0 °C(Predicted) |
| Dichte | 1.32±0.1 g/cm3(Predicted) |
| Lagerbedingungen | -20°C Freezer, Under Inert Atmosphere |
| Löslichkeit | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| Aggregatzustand | Solid |
| Farbe | White to Light Yellow |
| InChIKey | UDJQOKVZFMMKGS-GJMULMBRNA-N |
| SMILES | C1[C@]2(C)[C@H]3C(=O)C[C@]4(C)[C@@](OC(c5occc5)=O)(C(=O)CCl)[C@H](C)C[C@H]4[C@@H]3CCC2=CC(=O)C=1 |&1:1,3,7,9,22,25,26,r| |
Anwendungen & Verwendung
Verwenden
As impurity of Mometasone Furoate, (16α)-21-Chloro-17-[(2-furanylcarbonyl)oxy]-16-Methyl-pregna-1,4-diene-3,11,20-trione can be used as a topical corticosteroid used as an anti-inflammatory.