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1-Ethylpiperidin
N-ETHYLPIPERIDINE · Ethylpiperidine · Piperidine, 1-ethyl- · NSC 2090 · N-Ethylpiperidin · 1-Ethylpiperidin · 1-Ethylpiperidene · 1-ethvlpiperidine
Identifikatoren & physikalische Daten
| CAS No. | 766-09-6 |
|---|---|
| Summenformel | C7H15N |
| Durchschnittliche Molmasse | 113,2 g/mol |
| Monoisotopische Masse | 113,12044948 g/mol |
| SMILES | CCN1CCCCC1 |
| InChIKey | HTLZVHNRZJPSMI-UHFFFAOYSA-N |
| PubChem CID | 13007 |
| ChEMBL | CHEMBL25053 |
| ChEBI | CHEBI:39017 |
| EC No. | 212-161-6 |
| DTXSID | DTXSID1061102 |
| Lokaler Name | 1-Ethylpiperidin |
Chemische & physikalische Eigenschaften
| XLogP | 2 |
|---|---|
| Polarare Oberfläche (TPSA) | 3,2 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 1 |
| Frei drehbare Bindungen | 1 |
| Schwere Atome | 8 |
| Formalladung | 0 |
| Komplexität | 55,4 |
| Stoffklassen | Flammable agents - 3rd degree |
| SpringerMaterials Properties | 15N nuclear magnetic resonance spectrum |
| LogP (Verteilungskoeffizient) | 1.88 |
| Physical Description | 1-ethylpiperidine appears as a colorless liquid with the odor of pepper. Less dense than water. May irritate skin and eyes. Vapors heavier than air. Used as a solvent and to make other chemicals. |
| Schmelzpunkt | -20 °C |
| Siedepunkt | 131 °C(lit.) |
| Dichte | 0.824 g/mL at 25 °C(lit.) |
| Dampfdruck | 12.76hPa at 20℃ |
| Brechungsindex | n20/D 1.444(lit.) |
| Flammpunkt | 66 °F |
| Lagerbedingungen | Flammables area |
| Löslichkeit | 1-ethylpiperidine salt of benzylpenicillin is considerably less soluble in amyl acetate and acetone.50 G/L |
| pKa (Säurekonstante) | 10.45(at 23℃) |
| Aggregatzustand | Liquid |
| Farbe | Clear colorless to slightly yellow |
| pH | 12.2 (50g/l, H2O, 20℃) |
| Explosionsgrenze | 1.9-12.1%(V) |
| BRN | 102643 |
| Henry-Konstante | 3.9×10-1 mol/(m3Pa) at 25℃, Hilal et al. (2008) |
| InChI | 1S/C7H15N/c1-2-8-6-4-3-5-7-8/h2-7H2,1H3 |
| InChIKey | HTLZVHNRZJPSMI-UHFFFAOYSA-N |
| SMILES | CCN1CCCCC1 |
| LogP (Verteilungskoeffizient) | 1.89 at 25℃ |
| CAS Datenbank | 766-09-6(CAS DataBase Reference) |
| NIST chemische Informationen | Piperidine, 1-ethyl-(766-09-6) |
| EPA chemische Informationen | Piperidine, 1-ethyl- (766-09-6) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH225 (100%): Highly Flammable liquid and vapor [Danger Flammable liquids]P210, P233, P240, P241, P242, P243, P260, P261, P264, P264+P265, P270, P271, P280, P301+P316, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P303+P361+P353, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P363, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 213 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | Chemical: Piperidine, 1-ethyl-Piperidine, 1-ethyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Piperidine, 1-ethyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 16-05-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/11076Piperidine, 1-ethyl-: HSNO Approval: HSR001045 Approved with controlsThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| DOT-Kennzeichnung | Flammable Liquid Corrosive |
| Brandgefahren | Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]:· Flammable/combustible material. |
| Gesundheitsgefahren | Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]:· May cause toxic effects if inhaled or ingested. |
| DOT-Nummer und Handbuch | 2386 132 |
| Reaktive Gruppe | Amines, Phosphines, and Pyridines |
| Reactivity Alerts | Highly Flammable |
| Reactivity Profile | 1-ETHYLPIPERIDINE neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides. |
| DOT Hazard Classification | 1-EthylpiperidineUN2386Class 3 Flammable and combustible liquid (49 eCFR § 173.120)PG II: the degree of danger presented by the material is medium |
| Air and Water Reactions | Highly flammable. Soluble in water. |
| Hazard Classes and Categories | Flam. Liq. 2 (100%)Flammable agents - 3rd degree |
| Brandbekämpfung | Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]: |
| Freisetungsmaßnahmen | · CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.· ELIMINATE all ignition sources (no smoking, flares, sparks or flames) from immediate area. |
| Erste Hilfe | Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]:General First Aid: |
| Expositionsschutz und Persönliche Schutzausrüstung | · Wear positive pressure self-contained breathing apparatus (SCBA). |
| Freisetung ohne Brand | Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]: |
| Isolation and Evacuation | Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]:Immediate precautionary measure |
| Personal Protective Equipment (PPE) | Excerpt from ERG Guide 132 [Flammable Liquids - Corrosive]: |
| Emergency Response Planning Guidelines | · Some of these materials may react violently with water. |
| F | 10-23 |
| Wassergefährdungsklasse (WGK) | 1 |
| TSCA-Inventar-Status | TSCA listed |
| UN-Transportnummer | UN 2386 |
| Zollcode | 29333990 |
| RTECS-Nr. | TN0250000 |
| R-Sätze (R) | 11-20/22-36/37/38 |
| Gefahrensymbole | F,Xn |
| Sicherheitshinweise (S) | 26-36/37/39 |
| Gefahrenklasse | 3Acute Tox. 3 InhalationAcute Tox. 3 OralAcute Tox. 4 DermalEye Dam. 1Flam. Liq. 2Skin Corr. 1B |
| Verpackungsgruppe | II |
| Lagerklasse | 3 - Flammable liquids |
Anwendungen & Verwendung
Verwenden
In Room temperature phosphorescence of α-bromonaphthalene induced by cyclodextrin in the presence of hexahydropyridine or 1-ethylpiperidine and its application is described. The highest yields of 5-Bromopyrimidine (37%) were obtained by using 1-ethylpiperidine or triethylamine as condensing agent. Tributyltin hydride and 1-ethylpiperidine hypophosphite were mediated intermolecular radical additions to 2, 4, 6-trichlorophenyl vinyl sulfonate.