3-((2'-Carboxybiphenyl-4-yl)methyl)-2-cyclopropyl-7-methyl-3H-imidazo(4,5-b)pyridine
Grundinformationen
- CAS
135070-05-2- Standard-SMILES
Cc1ccnc2c1nc(C1CC1)n2Cc1ccc(-c2ccccc2C(=O)O)cc1- InChIKey
VWWMGPCUZVOLLK-UHFFFAOYSA-N- Summenformel
- C24H21N3O2
- Durchschnittliche Molmasse
- 383,4 g/mol
- Monoisotopische Masse
- 383,16337691
Überblick
a non-peptide angiotensin II-receptor antagonist; structure given in first source
Namen und Bezeichner
- Bevorzugter Name
- 3-((2'-Carboxybiphenyl-4-yl)methyl)-2-cyclopropyl-7-methyl-3H-imidazo(4,5-b)pyridine
- IUPAC
- 2-[4-[(2-cyclopropyl-7-methylimidazo[4,5-b]pyridin-3-yl)methyl]phenyl]benzoic acid
- Englischer Name
- E 4177
- Summenformel
- C24H21N3O2
- Molmasse
- 383.449
Namen und Synonyme
135070-05-2E41773-((2'-Carboxybiphenyl-4-yl)methyl)-2-cyclopropyl-7-methyl-3H-imidazo(4,5-b)pyridine(1,1'-Biphenyl)-2-carboxylic acid, 4'-((2-cyclopropyl-7-methyl-3H-imidazo(4,5-b)pyridin-3-yl)methyl)-RefChem:91968E-4177E 41772-[4-[(8-cyclopropyl-5-methyl-2,7,9-triazabicyclo[4.3.0]nona-1,3,5,7-tetraen-9-yl)methyl]phenyl]benzoic acidCHEMBL711622-[4-[(2-cyclopropyl-7-methylimidazo[4,5-b]pyridin-3-yl)methyl]phenyl]benzoic acid57G709; E 14774'-((2-cyclopropyl-7-methyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl)-[1,1'-biphenyl]-2-carboxylic acid
Weitere Namen anzeigen
1,1'-Biphenyl]-2-carboxylic acid, 4'-[(2-cyclopropyl-7-methyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl]-
VWWMGPCUZVOLLK-UHFFFAOYSA-NSCHEMBL685515orb1700680SCHEMBL30838455DTXSID50159239BDBM50049212AKOS040748296CS-0026848
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 4,4
- Polarare Oberfläche (TPSA)
- 68 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 4
- Frei drehbare Bindungen
- 5
- Schwere Atome
- 29
- Formalladung
- 0
- Komplexität
- 587
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological ClassificationAgents that antagonize ANGIOTENSIN II TYPE 1 RECEPTOR. Included are ANGIOTENSIN II analogs such as SARALASIN and biphenylimidazoles such as LOSARTAN. Some are used as ANTIHYPERTENSIVE AGENTS.
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