2,2,6,6-Tetramethyl-4-piperidon

2,2,6,6-Tetramethyl-4-piperidone

HCID 13220CAS 826-36-8
TeilstruktursucheÄhnliche Strukturen suchen

Grundinformationen

Standard-SMILES
CC1(C)CC(=O)CC(C)(C)N1
InChIKey
JWUXJYZVKZKLTJ-UHFFFAOYSA-N
Summenformel
C9H17NO
Durchschnittliche Molmasse
155,24 g/mol
Monoisotopische Masse
155,13101417

Namen und Bezeichner

Bevorzugter Name
2,2,6,6-Tetramethyl-4-piperidone
IUPAC
2,2,6,6-tetramethylpiperidin-4-one
Lokaler Name
2,2,6,6-Tetramethyl-4-piperidon
Englischer Name
Triacetonamine
Summenformel
C9H17NO
Molmasse
155.24

Namen und Synonyme

Triacetonamine826-36-82,2,6,6-Tetramethyl-4-piperidoneVincubineTempidonTMPoneDTXSID40415272K4430S3XPNSC-16579IKH-19DTXCID2021527RefChem:891346
Weitere Namen anzeigen
TEMPTAATETRAMETHYLPIPERIDINONETRIACETONEAMINEDL-22,2,6,6-Tetramethylpiperidone2,2,6,6-tetramethyl-4-piperidon
2,2,6,6-tetramethylpiperidone-4-toluene-p-sulfonate212-554-22,2,6,6-tetramethylpiperidin-4-oneTriacetonamin2,2,6,6-Tetramethyl-4-piperidinoneTriacetone amineVincubina2,2,6,6-Tetramethyl-4-oxopiperidine

Datenbank-Bezeichner

CAS
826-36-8
PubChem CID
13220
DTXSID
DTXSID4041527
ChEMBL
CHEMBL117614
ChEBI
CHEBI:177813
UNII
2K4430S3XP
EC Number
212-554-2
Nikkaji
J107D

Eigenschaften

Berechnete Struktureigenschaften

XLogP
0,5
Polarare Oberfläche (TPSA)
29,1 Ų
H-Brücken-Donoren
1
H-Brücken-Akzeptoren
2
Frei drehbare Bindungen
0
Schwere Atome
11

Experimentelle und physikochemische Eigenschaften

Melting Point34.9 °C
Physical DescriptionSolid
Dissociation Constants7.9

Physikochemische Eigenschaften

Schmelzpunkt
59 · 59-61 °C
Siedepunkt
105 · 105-105°C/18mm
Dichte
0.9796 · 0.9796 (rough estimate)
Brechungsindex
1.468 · 1.4680 (estimate)
Flammpunkt
73 °C · 73°C
storage temp.
2 · 2-8°C

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

Danger

H290 (77.1%): May be corrosive to metals [Warning Corrosive to Metals]；H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]；H314 (79.2%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]；H315 (20.8%): Causes skin irritation [Warning Skin corrosion/irritation]；H317 (79.2%): May cause an allergic skin reaction [Warning Sensitization, Skin]；H318 (77.1%): Causes serious eye damage [Danger Serious eye damage/eye irritation]；H319 (20.8%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (20.3%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]；H412 (79.2%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

P234, P260, P261, P264, P264+P265, P270, P271, P272, P273, P280, P301+P317, P301+P330+P331, P302+P352, P302+P361+P354, P304+P340, P305+P351+P338, P305+P354+P338, P316, P317, P319, P321, P330, P332+P317, P333+P317, P337+P317, P362+P364, P363, P390, P403+P233, P405, P406, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 192 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Regulatory Information · 2 Einträge

Status: Active Update: 13-03-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/14410

2,2,6,6-Tetramethyl-4-piperidone: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and Categories · 2 Einträge

Met. Corr. 1 (77.1%)；Acute Tox. 4 (100%)；Skin Corr. 1B (79.2%)；Skin Irrit. 2 (20.8%)；Skin Sens. 1 (79.2%)；Eye Dam. 1 (77.1%)；Eye Irrit. 2 (20.8%)；STOT SE 3 (20.3%)；Aquatic Chronic 3 (79.2%)

Acute toxicity (Oral) - Category 4；Skin corrosion/irritation - Category 1；Serious eye damage/eye irritation - Category 1；Skin sensitization - Category 1；Specific target organ toxicity - Single exposure - Category 2 (cardiovascular system, nervous system)

Regulatorische Informationen

Regulatory Information · 2 Einträge

Status: Active Update: 13-03-2019 https://echa.europa.eu/registration-dossier/-/registered-dossier/14410

2,2,6,6-Tetramethyl-4-piperidone: Does not have an individual approval but may be used under an appropriate group standard

Sicherheitsdaten

wgk
2
tsca
TSCA listed
hs_code
29333990
RTECS-Nr.
TO0127900
risk_code
34-22-36/37/38
hazard_code
C,Xn

Chemie und Industrie

Pharmakologische Informationen

Cellular LocationsCytoplasm；Extracellular

Verwendung und Herstellung

General Manufacturing Information4-Piperidinone, 2,2,6,6-tetramethyl-: ACTIVE
Anwendungen · 2 Einträge

BeschreibungTriacetonamine (CAS 826-36-8), also known as 2,2,6,6-tetramethyl-4-piperidone or TAA, is a key intermediate in the synthesis of HALS (hindered amine light stabilisers); Their ability to effectively inhibit polymer degradation by scavenging free radicals is based on their sterically hindered amine functional groups, which are capable of forming stable N-oxides as active intermediates (the Denysov cycle). TAA is also used in the synthesis of pharmaceuticals, piperidine nitroso radicals and pyrrolidone derivatives. For example, the oxidation of TAA or its derivatives yields the corresponding tetramethylpiperidine-N-oxide, namely TEMPO; the latter can be used as a polymerisation inhibitor, molecular weight regulator or oxidation catalyst[2].

Verwenden2,2,6,6-Tetramethyl-4-piperidinone (cas# 826-36-8) is a compound useful in organic synthesis.

Vor- und nachgelagerte Produkte

Anbieter50 Anbieter

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
河南国生化工有限公司17610068021 · [email protected]
河北展药生物科技有限公司15369953316 +8615369953316 · [email protected]
T&W GROUP021-61551611 13296011611 · [email protected]
爱斯特（成都）生物制药股份有限公司+86-28-85122536 85324413 · [email protected]

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