3'-Fluoro-2',3'-dideoxyguanosine
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Grundinformationen
- CAS
92562-88-4- Standard-SMILES
Nc1nc2c(ncn2[C@H]2C[C@H](F)[C@@H](CO)O2)c(=O)[nH]1- InChIKey
RTJUXLYUUDBAJN-KVQBGUIXSA-N- Summenformel
- C10H12FN5O3
- Durchschnittliche Molmasse
- 269,23 g/mol
- Monoisotopische Masse
- 269,09241746
Überblick
Lagociclovir is a small molecule drug. The usage of the INN stem '-ciclovir' in the name indicates that Lagociclovir is a antiviral, bicyclic heterocycle compound. Lagociclovir has a monoisotopic molecular weight of 269.09 Da.
Namen und Bezeichner
- Bevorzugter Name
- 3'-Fluoro-2',3'-dideoxyguanosine
- IUPAC
- 2-amino-9-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
- Englischer Name
- 2',3'-Dideoxy-3'-fluoro-guanosine
- Summenformel
- C10H12FN5O3
- Molmasse
- 269.23
Namen und Synonyme
3'-Fluoro-2',3'-dideoxyguanosineRefChem:152120Lagociclovir92562-88-42',3'-Dideoxy-3'-fluoroguanosineFddguoLagociclovir [INN]3'-FddG2',3'-DIDEOXY-3'-FLUORO-GUANOSINEMIV-210UU109JJU0UGuanosine, 2',3'-dideoxy-3'-fluoro-
Weitere Namen anzeigen
MIV 210Lagociclovir(MIV-210)Lagociclovir, 10 mM in DMSO2,3’-dideoxy-3’-fluoro guanosine, Lagociclovir2-amino-9-((2R,4S,5R)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-purin-6(9H)-one
UNII-UU109JJU0U2-AMINO-9-[(2R,4S,5R)-4-FLUORO-5-(HYDROXYMETHYL)OXOLAN-2-YL]-1H-PURIN-6-ONE2-amino-9-((2R,4S,5R)-4-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,9-dihydro-6H-purin-6-one2-amino-9-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-oneDTXSID902390442-amino-9-[(2R,4S,5R)-4-fluoro-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-oneRTJUXLYUUDBAJN-KVQBGUIXSA-NLAGOCICLOVIR [WHO-DD]
Datenbank-Bezeichner
- CAS
92562-88-4- PubChem CID
- 135431817
- DTXSID
DTXSID90239044- UNII
- UU109JJU0U
- Nikkaji
- J263.913K
Eigenschaften
Berechnete StruktureigenschaftenWird ergänzt
- XLogP
- -0,9
- Polarare Oberfläche (TPSA)
- 115 Ų
- H-Brücken-Donoren
- 3
- H-Brücken-Akzeptoren
- 6
- Frei drehbare Bindungen
- 2
- Schwere Atome
- 19
- Formalladung
- 0
- Komplexität
- 420
Physikochemische Eigenschaften
- Schmelzpunkt
- 253 · 253-255 °C (decomp)
- Siedepunkt
- 633.5 · 633.5±65.0 °C(Predicted)
- Dichte
- 2.01 · 2.01±0.1 g/cm3(Predicted)
- storage temp.
- -20 °C · Store at -20°C
- Löslichkeit
- Soluble in DMSO
- pka
- 14.44 · 14.44±0.10(Predicted)
- InChI
- InChI=1S/C10H12FN5O3/c11-4-1-6(19-5(4)2-17)16-3-13-7-8(16)14-10(12)15-9(7)18/h3-6,17H,1-2H2,(H3,12,14,15,18)/t4-,5+,6+/m0/s1
- InChIKey
- RTJUXLYUUDBAJN-KVQBGUIXSA-N
- SMILES
- OC[C@H]1O[C@@H](N2C3=C(C(NC(=N3)N)=O)N=C2)C[C@@H]1F
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.
Inhibitors of reverse transcriptase (RNA-DIRECTED DNA POLYMERASE), an enzyme that synthesizes DNA on an RNA template.
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