(Methoxymethyl)oxiran

1,2-Epoxy-3-methoxypropane

HCID 13589CAS 930-37-0

Grundinformationen

Standard-SMILES
COCC1CO1
InChIKey
LKMJVFRMDSNFRT-UHFFFAOYSA-N
Summenformel
C4H8O2
Durchschnittliche Molmasse
88,11 g/mol
Monoisotopische Masse
88,0524295

Überblick

Methyl glycidyl ether is a clear colorless liquid. (NTP, 1992)

Namen und Bezeichner

Bevorzugter Name
1,2-Epoxy-3-methoxypropane
IUPAC
2-(methoxymethyl)oxirane
Lokaler Name
(Methoxymethyl)oxiran
Englischer Name
GLYCIDYL METHYL ETHER
Summenformel
C4H8O2
Molmasse
88.11

Namen und Synonyme

Glycidyl methyl ether930-37-0Methyl glycidyl etherOxirane, (methoxymethyl)-1,2-EPOXY-3-METHOXYPROPANEGlycidol methyl ether(Methoxymethyl)oxiraneMethylglycidyl ether3-Methoxypropylene oxide3-Methoxy-1,2-epoxypropanePropane, 1,2-epoxy-3-methoxy-2,3-Epoxypropyl-methyl ether
Weitere Namen anzeigen
2-(Methoxymethyl)oxiraneoxirane,(methoxymethyl)-Epiol MEpimethylinDenacol EX-131glycidolmethylethermethylglycidylether
Oxirane, 2-(methoxymethyl)-NSC 86950CCRIS 2630HSDB 5444EINECS 213-216-7BRN 010250587MK2KA66TAI3-52869

Datenbank-Bezeichner

CAS
930-37-0
PubChem CID
13589
DTXSID
DTXSID9025613
UNII
87MK2KA66T
EC Number
213-216-7
Nikkaji
J60.714B

Eigenschaften

Berechnete Struktureigenschaften

XLogP
-0,2
Polarare Oberfläche (TPSA)
21,8 Ų
H-Brücken-Donoren
0
H-Brücken-Akzeptoren
2
Frei drehbare Bindungen
2
Schwere Atome
6

Experimentelle und physikochemische Eigenschaften

PolymersPlastics & Rubber -> Glycidyl Ethers
LogP0.03
Solubilitygreater than or equal to 100 mg/mL at 68.9 °F (NTP, 1992)
Flash Point · 2 Einträge

less than 69 °F (NTP, 1992)

Flash point < 21 °C

Physical Description · 2 Einträge

Methyl glycidyl ether is a clear colorless liquid. (NTP, 1992)

Colorless liquid; [CAMEO]

Physikochemische Eigenschaften

Siedepunkt
110 °C · 110°C
Dichte
0 · 0,98 g/cm3
Brechungsindex
1.408 · 1.4080-1.4140
Flammpunkt
24 °C · 24°C
storage temp.
Refrigerator
Löslichkeit
Chloroform (Slightly), Toluene (Slightly)

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 6 Einträge

Danger

H225 (75%): Highly Flammable liquid and vapor [Danger Flammable liquids]

P210, P233, P240, P241, P242, P243, P261, P262, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P316, P319, P321, P330, P332+P317, P337+P317, P361+P364, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 4 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Danger

H225: Highly Flammable liquid and vapor [Danger Flammable liquids]

Gefahrenhinweise

DOT LabelFlammable Liquid Poison
Fire HazardsThis chemical is flammable. (NTP, 1992)
Health HazardsExcerpt from ERG Guide 131 [Flammable Liquids - Toxic]:
Hazards SummaryA mutagen and primary irritant; Caused lacrimation and somnolence in lethal-dose feeding studies of rats; [RTECS] Emergency treatment: irritants; [HSDB] An irritant; [MSDSonline]
Reactive GroupEthers
Reactivity AlertsHighly Flammable

Sicherheit und Schutzausrüstung

Fire FightingFires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992)
First Aid · 1 Eintrag

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Nonfire Spill Response · 1 Eintrag

SMALL SPILLS AND LEAKAGE: If you should spill this chemical, use absorbent paper to pick up all liquid spill material. Seal the absorbent paper, as well as any of your clothing which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Wash any surfaces you may have contaminated with a strong soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Isolation and EvacuationExcerpt from ERG Guide 131 [Flammable Liquids - Toxic]:
Personal Protective Equipment (PPE) · 1 Eintrag

RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992)

Toxikologische Informationen

Non-Human Toxicity Excerpts · 3 Einträge

...THEY ARE VERY IRRITATING TO EYES, SKIN, & RESPIRATORY TRACT. /GLYCIDYL ETHERS/

1,2-EPOXY-3-METHOXYPROPANE WAS MUTAGENIC IN KLEBSIELLA PNEUMONIAE.

TOPICAL APPLICATION OF 0.1 ML ALIQUOT OF 1,2-EPOXY-3-METHOXYPROPANE TO CLIPPED & DEPILATED BACKS OF GUINEA PIGS 4 TIMES IN 10 DAYS. AFTER 2 WK REST PERIOD, GUINEA PIGS WERE CHALLENGED ON THE CLIPPED FLANKS. TWO OF THE 49 GUINEA PIGS TESTED BECAME SENSITIZED.

Sicherheitsdaten

tsca
TSCA listed
ridadr
3271
hs_code
2909200090
RTECS-Nr.
TZ3530000
risk_code
10
safety_code
16

Chemie und Industrie

Verwendung und Herstellung

Uses · 2 Einträge

Used as a research chemical; Not commercially produced in the US; [HSDB]

RESEARCH CHEMICAL

U.S. Exports · 2 Einträge

(1979) No Data

(1981) No Data

U.S. Imports · 2 Einträge

(1979) No Data

(1981) No Data

U.S. Production · 2 Einträge

(1979) NOT PRODUCED COMMERCIALLY IN U.S.

(1981) NOT PRODUCED COMMERCIALLY IN U.S.

Methods of ManufacturingPROBABLY BY REACTION OF 1-CHLORO-2-HYDROXY-3-METHOXYPROPANE WITH SODIUM HYDROXIDE
General Manufacturing InformationOxirane, 2-(methoxymethyl)-: ACTIVE

Anwendungen

Verwenden2-(Methoxymethyl)oxirane is used in the fixation of biological tissues or in collagen bioprosthetic fixation processes.

Anbieter50 Anbieter

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