Laurolactam

Polyamide12 · NYLON 12 ISO 9001：2015 REACH · Ntylon-12 · POLYLAURYLLACTAM · Lauryl lactam, homopolymer · azacyclotridecan-2-one,homopolymer · Azacyclotridecane-2-one,homopolymer

https://huagongshe.com/de/chemical/13690

Identifikatoren & physikalische Daten

CAS No.	25038-74-8
Summenformel	C12H23NO
Durchschnittliche Molmasse	197,32 g/mol
Monoisotopische Masse	197,17796436 g/mol
SMILES	O=C1CCCCCCCCCCCN1
InChIKey	JHWNWJKBPDFINM-UHFFFAOYSA-N
PubChem CID	13690
ChEMBL	CHEMBL3181948
ChEBI	CHEBI:172332
EC No.	213-424-8
DTXSID	DTXSID1027344

Chemische & physikalische Eigenschaften

XLogP	2,8
Polarare Oberfläche (TPSA)	29,1
H-Brücken-Donoren	1
H-Brücken-Akzeptoren	1
Frei drehbare Bindungen	0
Schwere Atome	14
Formalladung	0
Komplexität	156
Polymers	Plastics & Rubber -> Other Monomers
SpringerMaterials Properties	15N nuclear magnetic resonance spectrum
Löslichkeit	VIRTUALLY INSOL IN WATER
Dampfdruck	0.00000731 [mmHg]
Food Contact Substances	FCS -> FDA Cumulative Estimated Daily Intake (CEDI)FCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR
Physical Description	Dry PowderLarge CrystalsSolid[eChemPortal: SIDSUNEP] Very faintly beige crystalline lumps[MSDSonline]
Collision Cross Section	148.2 Å² [M+H]+ [CCS Type: DTBuffer gas: N2Ionization: APCI+Dataset: TOXCASTSource Identifier: DTXSID1027344]
Schmelzpunkt	176 °C
Dichte	1.01 g/mL at 25 °C(lit.)
Aggregatzustand	pellets
Kosmetik-Inhaltsstoffe Funktionen	BULKINGVISCOSITY CONTROLLINGOPACIFYING
LogP (Verteilungskoeffizient)	3.123 (est)
EPA chemische Informationen	Azacyclotridecan-2-one, homopolymer (25038-74-8)

Sicherheit & Vorschriften

GHS-Einstufung	This chemical does not meet GHS hazard criteria for 96.6% (115 of 119) of all reports.Not ClassifiedAggregated GHS information provided per 119 reports by companies from 2 notifications to the ECHA C&L Inventory.WarningH371: May cause damage to organs [Warning Specific target organ toxicity, single exposure]P260, P264, P270, P273, P308+P316, P405, and P501 (click each P-code to see the statement)
Regulatorische Informationen	Chemical: Azacyclotridecan-2-oneAzacyclotridecan-2-one is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Azacyclotridecan-2-one are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)Status: Active Update: 12-04-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/13738
Gefahrenübersicht	May cause irritation[MSDSonline] See Caprolactam.
Hazard Classes and Categories	Not ClassifiedSpecific target organ toxicity - Single exposure - Category 2 (central nervous system, digestive system)
Non-Human Toxicity Excerpts	ALL THE THIOLACTAMS STUDIED CAUSED CLONIC AND TONIC CONVULSIONS IN MICE A FEW SEC AFTER IP ADMIN. THE VARIATION IN THE ACUTE BASAL TOXICITY OF THE THIOLACTAMS WAS MAINLY DUE TO THE CHANGE IN THE LIPOHYDROPHILIC CHARACTER. THE DIPOLE MOMENT APPEARS TO PLAY A SIGNIFICANT ROLE IN DETERMINING THE CONVULSANT ACTIVITY IN THE TOXICITY OF THIOLACTAMS, LACTAMS, & GAMMA-THIOBUTYROLACTONE.FOR LACTAMS WITH SMALL RING SIZE, CNS STIMULATION APPEARED TO BE DOMINANT IN MICE THAT WERE INJECTED IP WITH A SERIES OF LOGARITHMIC DOSES (30, 100, 300, AND 1000 MG/KG (GROUPS OF 6 ANIMALS, 3 MALES & 3 FEMALES). 2-AZACYCLOTRIDECANONE CAUSED TREMBLING AT 500 MG/KG IN 6/6 MICE.
Wassergefährdungsklasse (WGK)	3
TSCA-Inventar-Status	TSCA listed

Anwendungen & Verwendung

Verwenden

nylon 12 is a bulking and opacifying agent that provides good feel and good elasticity to moisturizers and makeup preparations, including foundations. nylon 12 reduces oiliness. It is a polyamide derivative of acid 12-aminododecanioic.

Herstellung & Synthese

synthetische

Nylon 12 is produced by heating dodecyl lactam at about 300°C in the presence of aqueous phosphoric acid. The polymerization of dodecyllactam does not involve an equilibrium reaction (unlike the polymerization of caprolactam) and hence an almost quantitative yield of polymer is obtained and the removal of low molecular weight material is unnecessary.