2-Phenylindol

2-Phenylindole

HCID 13698CAS 948-65-2
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Grundinformationen

Standard-SMILES
c1ccc(-c2cc3ccccc3[nH]2)cc1
InChIKey
KLLLJCACIRKBDT-UHFFFAOYSA-N
Summenformel
C14H11N
Durchschnittliche Molmasse
193,24 g/mol
Monoisotopische Masse
193,08914935

Überblick

2-phenyl-1H-indole is a phenylindole.

Namen und Bezeichner

Bevorzugter Name
2-Phenylindole
IUPAC
2-phenyl-1H-indole
Lokaler Name
2-Phenylindol
Englischer Name
2-Phenylindole
Summenformel
C14H11N
Molmasse
193.24

Namen und Synonyme

2-Phenylindole2-PHENYL-1H-INDOLE948-65-21H-Indole, 2-phenyl-Indole, 2-phenyl-Stabilizer Ialpha-PhenylindoleMQD44HV3P1NSC-15776DTXSID80613431H-Indole, 2-phenylRefChem:89089
Weitere Namen anzeigen
1H-Indole,2-phenyl-NSC 15776stabilizeri-PhenylindoleA-PHENYLINDOLa-Phenylindole2-phenyl-indol
DTXCID3048940213-436-32-PHENYL INDOLEMFCD00005608.alpha.-PhenylindolePhenylindoleMLS002638448F1918-0028

Datenbank-Bezeichner

CAS
948-65-2
PubChem CID
13698
DTXSID
DTXSID8061343
ChEMBL
CHEMBL75756
ChEBI
CHEBI:113541
UNII
MQD44HV3P1
EC Number
213-436-3
Nikkaji
J36.864D

Eigenschaften

Berechnete Struktureigenschaften

XLogP
3,8
Polarare Oberfläche (TPSA)
15,8 Ų
H-Brücken-Donoren
1
H-Brücken-Akzeptoren
0
Frei drehbare Bindungen
1
Schwere Atome
15

Experimentelle und physikochemische Eigenschaften

Chemical ClassesNitrogen Compounds -> Indoles
SpringerMaterials PropertiesLuminescence
Solubility0.7 [ug/mL] (The mean of the results at pH 7.4)
Physical DescriptionPowder; [Alfa Aesar MSDS]

Physikochemische Eigenschaften

Schmelzpunkt
188 · 188-190 °C (lit.)
Siedepunkt
250 °C/10 · 250 °C/10 mmHg (lit.)
Dichte
1.1061 · 1.1061 (rough estimate)
Brechungsindex
1.585 · 1.5850 (estimate)
Flammpunkt
250 °C/10mm · 250°C/10mm
storage temp.
Sealed in dry,Room Temperature

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 5 Einträge

This chemical does not meet GHS hazard criteria for 2.2% (1 of 45) of reports.

Danger

H315 (93.3%): Causes skin irritation [Warning Skin corrosion/irritation]

P261, P264, P264+P265, P271, P273, P280, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P332+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 45 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Regulatory InformationChemical: 1H-Indole, 2-phenyl-
Hazards SummaryMay cause irritation; [Alfa Aesar MSDS] See 3-Methylindole.
Hazard Classes and CategoriesSkin Irrit. 2 (93.3%)

Sicherheitsdaten

wgk
3
tsca
TSCA listed
hs_code
29309090
RTECS-Nr.
NM1272500
risk_code
37/38-41
hazard_code
Xi

Chemie und Industrie

Verwendung und Herstellung

General Manufacturing Information1H-Indole, 2-phenyl-: ACTIVE
Anwendungen · 1 Eintrag

VerwendenReactant for preparation of: • ;Oxopyrrolidine analogs via iodine-catalyzed Markovnikov addition1• ;Tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles as potential anticancer immunomodulators2• ;Organic light emitting diodes (OLEDs)3• ;Anti inflammatory agents4• ;Potential cyclooxygenase-1 (COX-1)/cyclooxygenase-2 (COX-2) inhibitors5• ;Agents for cancer and malaria therapy6• ;Antifungal and antibacterial agents7• ;Fluorescent probes8Reactant in:• ;Difluorohydroxylation reactions†• ;Mannich-type reactions†

Darstellung · 1 Eintrag

synthetische2-phenylindole is prepared by condensing phenylhydrazine and acetophenone, and then closing the ring in the presence of zinc chloride. or it can be prepared by heating bromoacetophenone with excess aniline, or heating N-(2-methylphenyl)benzamide and sodium ethoxide at 360-380℃ in isolation from air.

Vor- und nachgelagerte Produkte

Anbieter50 Anbieter

梯希爱(上海)化成工业发展有限公司021-67121386 · [email protected]
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
INTATRADE GmbH+49 3493/605464 · [email protected]
河北创海生物科技有限公司+86-86-13131129325 · [email protected]
河北展药生物科技有限公司15369953316 +8615369953316 · [email protected]

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