HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Nifuroxazid
(nitro-5’furfurylidene-2’)hydroxy-4benzhydrazide · Adral · 27-109RC · Nifuzide · RC 30-109 · diarlidan · dicoferin · ercefurol
Identifikatoren & physikalische Daten
| CAS No. | 965-52-6 |
|---|---|
| Summenformel | C12H9N3O5 |
| Durchschnittliche Molmasse | 275,22 g/mol |
| Monoisotopische Masse | 275,0542204 g/mol |
| SMILES | O=C(NN=Cc1ccc([N+](=O)[O-])o1)c1ccc(O)cc1 |
| InChIKey | YCWSUKQGVSGXJO-UHFFFAOYSA-N |
| PubChem CID | 13764 |
| ChEMBL | CHEMBL1309180 |
| DTXSID | DTXSID4045343 |
| Lokaler Name | Nifuroxazid |
Chemische & physikalische Eigenschaften
| XLogP | 2,1 |
|---|---|
| Polarare Oberfläche (TPSA) | 121 |
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 6 |
| Frei drehbare Bindungen | 3 |
| Schwere Atome | 20 |
| Formalladung | 0 |
| Komplexität | 387 |
| Human Drugs | Pharmaceuticals |
| Endocrine Disruptors | Potential endocrine disrupting compound |
| Schmelzpunkt | 281-283°C |
| Siedepunkt | 418.17°C (rough estimate) |
| Dichte | 1.3877 (rough estimate) |
| Brechungsindex | 1.5700 (estimate) |
| Lagerbedingungen | Inert atmosphere,2-8°C |
| Löslichkeit | Practically insoluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in methylene chloride. |
| pKa (Säurekonstante) | 8.36±0.15(Predicted) |
| Aggregatzustand | Solid |
| Farbe | Yellow |
| BRN | 4264976 |
| Hauptanwendungen | clinical testing |
| InChI | InChI=1S/C12H9N3O5/c16-9-3-1-8(2-4-9)12(17)14-13-7-10-5-6-11(20-10)15(18)19/h1-7,16H,(H,14,17) |
| InChIKey | YCWSUKQGVSGXJO-UHFFFAOYSA-N |
| SMILES | C(NN=CC1=CC=C([N+]([O-])=O)O1)(=O)C1=CC=C(O)C=C1 |
| CAS Datenbank | 965-52-6(CAS DataBase Reference) |
Sicherheit & Vorschriften
| Wassergefährdungsklasse (WGK) | 3 |
|---|---|
| RTECS-Nr. | DH2528300 |
| Toxizität | LD50 intraperitoneal in mouse: 1gm/kg |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
Nifuroxazide is an intestinal antiseptic. Nifuroxazide, is still used as a veterinary drug illegally in some countries. SEE H829102 as a test for antibiotic in broiler chickens.