5,12-Dihydrochino[2,3-b]acridin-7,14-dion

Plastics -> Polyolefin-I; PUR; Polyolefin-II; PVC (soft); ABS; PVC (rigid); PET; PMMA; PA; PC; (E)PS

Plastics -> Pigments agents

Red to violet solid with blueish or yellowish tint depending upon crystalline form.

particle characteristics: thin plates

Insoluble in water

Insoluble in organic solvents and dispersion media.

FCS -> FDA Cumulative Estimated Daily Intake (CEDI)

FCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR

FCS -> FDA Inventory of Effective Food Contact Substance (FCS) Notifications

FCS -> FDA Inventory of Effective Food Contact Substance (FCS) Notifications

Liquid; Other Solid; Dry Powder; Other Solid; CBI

Red to violet solid; Bluish or yellowish tint depending of form; [HSDB] Red odorless powder; [MSDSonline]

Solid

This chemical does not meet GHS hazard criteria for 99.6% (760 of 763) of all reports.

Not Classified

Aggregated GHS information provided per 763 reports by companies from 4 notifications to the ECHA C&L Inventory.

Chemical: Quino[2,3-b]acridine-7,14-dione, 5,12-dihydro-

Quino[2,3-b]acridine-7,14-dione, 5,12-dihydro- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Quino[2,3-b]acridine-7,14-dione, 5,12-dihydro- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

Status: Active Update: 23-11-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/14755

Quino[2,3-b]acridine-7,14-dione, 5,12-dihydro-: Does not have an individual approval but may be used under an appropriate group standard

Skin reactions have been reported: inflammation in a tattoo after sun exposure and acne-like changes on the face of a child colored with a red felt-tip pen; Also acne-like reaction on the skin of rabbits after coloring with red felt-tip pen; [HSDB] No known adverse effects on human health; Not an irritant; Not a sensitizer; [MSDSonline] See Acridine.

A BRIEF DESCRIPTION OF THE CHEMICAL PROPERTIES, DEVELOPMENT, & EFFORTS TOWARD GAINING APPROVAL OF THE QUINACRIDONE PIGMENT VIOLET #19 (LINEAR TRANS QUINACRIDONE) BY THE FDA IS PRESENTED.[VIOLET #19--POTENTIAL NEW COSMETIC COLOR; COSMET TOILET 94(MAY) 19 (1979)]

[ITC/USEPA; Information Review #315 (Draft) Cinquasia Red 1982]

Much of cinquasia red will be bound up in the components of landfills, junkyards, and general dump sites.

Terrestrial: The insolubility of cinquasia red will cause it to collect in soils and sediments.

Aquatic: Due to its insolubility, cinquasia red may reside in the water column for a substantial period, long enough to become part of deep sea sediments.

Two different red pigments used for tattooing were found to give rise to inflammatory reactions in the skin. No inorganic component was found in the pigments. NMR and MS analyses elucidated the molecular structures ... a red-violet pigment was found to be linear quinacridone. A strong exposure to UV-light was reported in most cases prior to the onset of the inflammation.

Acne-like changes were observed on a child's cheek after coloring them with a red felt tip pen. Numerous comedos appeared around a red tattoo colored with felt tip pen ink on a 16-yr-old girl.

Released to the environment as fugitive dust during manufacturing and end use.

EPA reported that the waste streams from the manufacture of cinquasia red are brines which contain small amounts of organic chemicals and strong acid wastes.

Pigment Violet #19 was nonmutagenic by Ames test.

In rabbits ... /pigment violet 19/ in felt tip pens produced a comedo type reaction.

Used as pigment (paints, printing inks, plastics, rubber, alkyd resin enamels, textile emulsion inks, textiles, nitrocellulose, vinyl, and acrylic lacquers) and sensitizing dye in color photo electrophoresis; Used to tone and make other pigments; [HSDB]

Painting (Pigments, Binders, and Biocides) [Category: Paint]

PAINTS, PRINTING INKS, PLASTICS, RUBBER

Cinquasia red is used a sensitizing dye in color photoelectrophoresis.

Pigment in textiles

As colorants for plastics, quinacridone pigments may be used in all resins except nylon-66 and polystyrene./Quinacridone Pigments/

(1979) No Data

(1981) No Data

(1979) 2.49X10+7 GRAMS (PRINCPL CUSTMS DISTS)

(1981) 6.21X10+6 GRAMS (PRINCPL CUSTMS DISTS)

2023: 1,000,000 - <2,500,000 lb

1.2 million lbs.

(1979) 7.11X10+8 GRAMS

(1981) 6.25X10+8 GRAMS

Quinacridone pigment use in automotive finishes accounts for the majority of the consumption of cinquasia red, with lesser quantities finding end uses in PVC manufacturing and the textile industry.

ESSENTIALLY 100% AS A PIGMENT

The major commercial production methods involve cyclization of 2,5-di(arylamino)terephthalic acids and esters.

The manufacturing process /of cinquasia red/ required three steps: (1) halogenation of terephthalic acid, (2) reaction of aniline with 2,5-dihaloterephthalic acid, and (3) cyclization of 2,5-dianilinoterephthalic acid to finished pigment.

HEATING OF DIALKYL(C1-C3)-2,5-DIARYLAMINO-3,6-DIHYDROTEREPHTHALATE IN AN INERT, HIGH-BOILING MEDIUM FOLLOWED BY OXIDATION

Plastics -> Polymer Type -> Polyolefin-I; PUR; Polyolefin-II; PVC (soft); ABS; PVC (rigid); PET; PMMA; PA; PC; (E)PS

Plastics -> Pigments agents

Cosmetics -> Hair dyeing; Cosmetic colorant

Synthetic Dye and Pigment Manufacturing

Quino[2,3-b]acridine-7,14-dione, 5,12-dihydro-: ACTIVE

Importer: American Hoechst Corporation, Rte 202-206 North, Bridgewater, NJ, 08876

Importer: Dainippon Ink & Chems. America Inc., 200 Park Avenue, New York, NY, 10017

Importer: BASF Wyandotte Corp., 100 Cherry Hill Rd., Parsippany, NJ, 07054.