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Trimethylzinnchlorid
CHLOROTRIMETHYLSTANNANE · Trimethylstannyl chloride · (CH3)3SnCl · trimethylstannylchloride · TRIMETHYLTIN(IV) CHLORIDE · 1mTHF · tin chL · SKL1103
Identifikatoren & physikalische Daten
| CAS No. | 1066-45-1 |
|---|---|
| Summenformel | C3H9ClSn |
| Durchschnittliche Molmasse | 199,27 g/mol |
| Monoisotopische Masse | 199,94147267 g/mol |
| SMILES | [CH3][Sn]([CH3])([CH3])[Cl] |
| InChIKey | KWTSZCJMWHGPOS-UHFFFAOYSA-M |
| PubChem CID | 14016 |
| EC No. | 213-917-8 |
| DTXSID | DTXSID6042496 |
| Lokaler Name | Trimethylzinnchlorid |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 0 |
|---|---|
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 0 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 5 |
| Formalladung | 0 |
| Komplexität | 28,4 |
| Stoffklassen | Metals -> Tin Compounds, OrganicReactive agents - 1st degree |
| Color/Form | Colorless needles |
| Löslichkeit | Soluble in chloroform and organic solvents.Miscible in waterChloroform (Slightly)Soluble in water, chloroform and organic solvents. |
| Endocrine Disruptors | Potential endocrine disrupting compound |
| Siedepunkt | 154-156 °C148 °C |
| Decomposition | When heated to decomposition it emits toxic fumes of chlorides. |
| Schmelzpunkt | 99 °F (EPA, 1998)37.5 °C42 °C37-39 °C (lit.) |
| Dampfdruck | 3 [mm Hg] @25 °C |
| Physical Description | Trimethyltin chloride is a solid. (EPA, 1998)Colorless solidmp = 37.5 deg C[HSDB] White crystalline solid[MSDSonline] |
| Dichte | 0.988 g/mL at 25 °C |
| Flammpunkt | 207 °F |
| Lagerbedingungen | Poison room |
| Aggregatzustand | Liquid |
| Wichte | 1.356 |
| Farbe | White |
| Geruch | Strong unpleasant stenchno threshold data available |
| BRN | 3535111 |
| Stabilität | Moisture Sensitive |
| InChI | 1S/3CH3.ClH.Sn/h3*1H3/q+1/p-1 |
| InChIKey | KWTSZCJMWHGPOS-UHFFFAOYSA-M |
| SMILES | C[Sn](C)(C)Cl |
| CAS Datenbank | 1066-45-1(CAS DataBase Reference) |
| EPA chemische Informationen | Trimethyltin chloride (1066-45-1) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH300 (100%): Fatal if swallowed [Danger Acute toxicity, oral]P260, P262, P264, P270, P271, P273, P280, P284, P301+P316, P302+P352, P304+P340, P316, P320, P321, P330, P361+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 47 reports by companies from 4 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | Chemical: Stannane, chlorotrimethyl-Trimethyltin chloride: HSNO Approval: HSR004752 Approved with controlsThe New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.) |
| DOT-Kennzeichnung | Poison |
| Brandgefahren | When heated to decomposition, it emits toxic fumes of chlorides. Avoid decomposing heat. (EPA, 1998) |
| Gesundheitsgefahren | (Non-Specific -- Tin Compounds, Organic) The material is an irritant to the skin and gastrointestinal tract. Contact may specifically damage the following target organs: central nervous system, eyes, liver, urinary tract, and skin. (EPA, 1998) |
| Gefahrenübersicht | In 1981, six employees in a chemical firm were exposed to trimethyltin chloride while working at the access opening of the reactor. All patients were hospitalized, and one patient died 10 days after the accident. Patients had headache, tiredness, hearing loss, disorientation, and other neurological symptoms. [HSDB] Of the trialkyltins, triethyltin and trimethytin are the most toxic. [ACGIH] An irritantCan be absorbed through skin[MSDSonline] See Tin, organic compounds. |
| Reaktive Gruppe | Salts, Acidic |
| Reactivity Profile | TRIMETHYLTIN CHLORIDE is in the family of tin compounds widely used as stabilizers for plastics, additives to paint(as antifouling agents). Some have catalytic properties. Examples include butyl tin, dibutyl tin oxide. Their main hazard is associated with their high toxicity, in skin adsorption or inhalation. |
| Air and Water Reactions |
Anwendungen & Verwendung
Verwenden
Trimethyltin chloride is an organotin reagent widely used in transferring trimethylstannyl groups onto the substrates to synthesize various organostannanes. Trimethylstannyl compounds derived from this reagent, are extensively used in the palladium-catalyzed Stille coupling reactions.