Barium lithol red｜Huagongshe

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HCID 14199Erstellt: 27. Oktober 2026

Bariumbis[2-[(2-hydroxynaphthyl)azo]naphthalinsulfonat]

Red 49:1 · 3144 Red R · C.I.15630:1 · C.I.P.R.49:1 · lithol red ba · Barium lithol · Lithol scarlet · D & C Red No.12

https://huagongshe.com/de/chemical/14199

Molekülstruktur von Bariumbis[2-[(2-hydroxynaphthyl)azo]naphthalinsulfonat]

Identifikatoren & physikalische Daten

CAS No.	1103-38-4
Summenformel	C40H26BaN4O8S2
Durchschnittliche Molmasse	892,1 g/mol
Monoisotopische Masse	892,02445299 g/mol
SMILES	O=S(=O)([O-])c1c(N=Nc2c(O)ccc3ccccc23)ccc2ccccc12.O=S(=O)([O-])c1c(N=Nc2c(O)ccc3ccccc23)ccc2ccccc12.[Ba+2]
InChIKey	LFZDEAVRTJKYAF-UHFFFAOYSA-L
PubChem CID	14199
EC No.	214-160-6
DTXSID	DTXSID0027359
Lokaler Name	Bariumbis[2-[(2-hydroxynaphthyl)azo]naphthalinsulfonat]

Chemische & physikalische Eigenschaften

Polarare Oberfläche (TPSA)	221
H-Brücken-Donoren	2
H-Brücken-Akzeptoren	12
Frei drehbare Bindungen	4
Schwere Atome	55
Formalladung	0
Komplexität	634
Stoffklassen	Dyes -> Azo Dyes
Physical Description	Dry PowderSolid[IUCLID] Red solid[MSDSonline]
Dichte	1.66[at 20℃]
LogP (Verteilungskoeffizient)	4.024 (est)
CAS Datenbank	1103-38-4(CAS DataBase Reference)
EPA chemische Informationen	C.I. Pigment Red 49, barium salt (2:1) (1103-38-4)

Sicherheit & Vorschriften

GHS-Einstufung	This chemical does not meet GHS hazard criteria for 99.6% (269 of 270) of all reports.Not ClassifiedAggregated GHS information provided per 270 reports by companies from 3 notifications to the ECHA C&L Inventory.
Regulatorische Informationen	Chemical: 1-Naphthalenesulfonic acid, 2-[(2-hydroxy-1-naphthalenyl)azo]-, barium salt (2:1)1-Naphthalenesulfonic acid, 2-[2-(2-hydroxy-1-naphthalenyl)diazenyl]-, barium salt (2:1) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1-Naphthalenesulfonic acid, 2-[2-(2-hydroxy-1-naphthalenyl)diazenyl]-, barium salt (2:1) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)REACH registered substance: Barium bis[2-[(2-hydroxynaphthyl)azo]naphthalenesulphonate] (EC: 214-160-6)1-Naphthalenesulfonic acid, 2-(2-hydroxy-1-naphthalenyl)azo-, barium salt (2:1): Does not have an individual approval but may be used under an appropriate group standard
Weitere Sicherheitsinformationen	IMAP assessments - 1-Naphthalenesulfonic acid, 2-[(2-hydroxy-1-naphthalenyl)azo]-, barium salt (2:1): Human health tier I assessment
Gefahrenübersicht	Oral LD50 (rat) >5,000 mg/kg[RTECS] A mild eye irritant[MSDSonline]
Special Reports	European Commission, ESISIUCLID Dataset, Barium bis [2-[(2-hydroxynaphthyl)azo]naphthalenesulphonate (1103-38-4) (2000 CD-ROM edition) contains information on use, toxicology, and environmental effects of this chemical as supplied to the European Union by industry .[Available from, as of November 17, 2010: http://esis.jrc.ec.europa.eu/]
DOT Emergency Guidelines	/GUIDE 154: SUBSTANCES - TOXIC AND/OR CORROSIVE (NON-COMBUSTIBLE)/ Health: TOXICinhalation, ingestion, or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution. /Barium compound, NOS/

Anwendungen & Verwendung

Verwenden

Pigment Red 49:1 is a red azo pigment, popular as artists'' coloring materials in the first half of the twentieth century

Shipment Methods and Regulations

No person may /transport,/ offer or accept a hazardous material for transportation in commerce unless that person is registered in conformance ... and the hazardous material is properly classed, described, packaged, marked, labeled, and in condition for shipment as required or authorized by ... /the hazardous materials regulations (49 CFR 171-177)./The International Air Transport Association (IATA) Dangerous Goods Regulations are published by the IATA Dangerous Goods Board pursuant to IATA Resolutions 618 and 619 and constitute a manual of industry carrier regulations to be followed by all IATA Member airlines when transporting hazardous materials.The International Maritime Dangerous Goods Code lays down basic principles for transporting hazardous chemicals. Detailed recommendations for individual substances and a number of recommendations for good practice are included in the classes dealing with such substances. A general index of technical names has also been compiled. This index should always be consulted when attempting to locate the appropriate procedures to be used when shipping any substance or article.

Brandbekämpfungsverfahren

If material on fire or involved in fire: Extinguish fire using agent suitable for type of surrounding fire. (Material itself does not burn or burns with difficulty.) Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. Use foam, dry chemical, or carbon dioxide. Keep run-off water out of sewers and water sources. /Barium compounds, NOS/Wear positive pressure self-contained breathing apparatus. /Barium compounds NOS/

Reinigungsverfahren

Environmental considerations - land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner./ Cover solids with a plastic sheet to prevent dissolving in rain or fire fighting water. Dike surface flow using soil, sand bags, foamed polyurethane, or foamed concrete. Absorb bulk liquid with fly ash, cement powder, or commercial sorbents. /Barium/Environmental considerations - water spill: Use natural barriers or oil spill control booms to limit spill travel. Use natural deep water pockets, excavated lagoons, or sand bag barriers to trap material at bottom. Remove trapped material with suction hoses. /Barium/Environmental considerations - air spill: Apply water spray or mist to knock down vapors. /Barium/

Entsorgungsverfahren

Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number D005, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste.... Ion exchange, lime softening and reverse osmosis are effective to remove barium from drinking water. Conventional coagulation/filtration processes are not effective to remove barium from drinking water. /Barium ion/Package lots. Place in a separate labeled container for recycling or disposal. Small quantities. Wear nitrile rubber gloves, laboratory coat, and eye protection. Avoid breathing dust. Dissolve the barium salt in the minimum volume of water. For each gram of barium salt, add 15 mL of 10% sodium sulfate solution. Let stand for 1 week. Test for completeness of precipitation by adding a few drops of 10% sodium sulfate solution. If required, add more sodium sulfate solution until no further precipitation occurs. Decant supernatant liquid or filter solid. Treat solid as normal refuse. Wash liquid into drain. /Barium salt/

Preventive Measures

If employees' clothing has had any possibility of being contaminated with barium carbonate, barium chloride, barium nitrate ... or liq containing these cmpd, employees should change into uncontaminated clothing before leaving the work premises. ... Clothing contaminated with barium carbonate, barium chloride, barium nitrate ... should be placed in closed containers for storage until it can be discarded or until provision is made for the removal of contaminant from the clothing. If the clothing is to be laundered or otherwise cleaned to remove the contaminant, the person performing the operation should be informed of contaminant's hazardous properties. ... Non-impervious clothing which becomes contaminated with barium carbonate, barium chloride, barium nitrate ... should be removed promptly and not reworn until the contaminant is removed from the clothing. /Soluble barium cmpd/Skin that becomes contaminated with barium carbonate, barium chloride, or barium nitrate should be promptly washed or showered to remove any contaminant. In the case of barium carbonate, employees should use soap or mild detergent and water for washing purposes. /Soluble barium cmpd/Eating and smoking should not be permitted in areas where solid barium carbonate, barium chloride, barium nitrate ... or liq containing these cmpd are handled, processed, or stored. Employees who handle barium carbonate, barium chloride, barium nitrate ... or liq containing these cmpd should wash their hands thoroughly before eating, smoking, or using toilet facilities. In the case of barium carbonate, employees should use soap or mild detergent and water for washing purposes. /Soluble barium cmpd/To keep dust concn below recommended levels, processes should be enclosed &/or exhaust ventilation installed. Adequate washing & other sanitary facilities should be provided ... & rigorous personal hygiene measures should be encouraged. Smoking & consumption of food & beverages in workshops should be prohibited. Floors in workshops should be made of impermeable materials & frequently washed down. /Barium & compounds/For more Preventive Measures (Complete) data for Barium lithol red (10 total), please visit the HSDB record page.

Personal Protective Equipment (PPE)	The only foreseeable danger would be from dust. The effects of this on the workforce can be minimized by the use of local exhaust ventilation and by wearing a suitable respirator if necessary.[European Commission, ESISIUCLID Dataset, Barium bis [2-

Ökotoxizitätswerte	EC50Species: AlgaeConditions: estimationConcentration: 0.038 mg/L for 96 hr. The conduction of an algae test with C.I. Pigment Red 49 is problematic as the substance leads to a strong coloring of the test solution and therefore to a reduction of light intensity. Therefore, the assessment is made on the basis /short term tests on related chemicals/ and computer model estimation.

Non-Human Toxicity Excerpts

/LABORATORY ANIMALS: Acute Exposure/ Skin irritation to rabbits: negative./LABORATORY ANIMALS: Chronic Exposure or Carcinogenicity/ Two hundred and fifty 3-week-old Osborne-Mendel rats divided into 5 groups of 50 rats each, and each group equally divided by sex, were started on a 2-year feeding experiment on D & C Red No. 10 which was mixed into the diet at levels of 1%, 0.25%, 0.05%, 0.01%, and 0% (controls) and fed ad libitum. The color had no apparent effect on the growth rate of test rats. Percentage of rats surviving on the 2-year test was increased by the addition of the color to the diet. Slight to moderate splenic enlargement was noted in 1% and 0.25% feeding level rats. Grossly 42% of the rats had pneumonia, 17% had nephritis, 17% had pituitary lesions, and 43% of the females had mammary tumors. Other incidental gross pathology randomly distributed among these 250 rats included lymphosarcoma in 7 rats, subcutaneous tumors in 5 males, endometrial sarcomas in 4 females, thyroid tumors in 4 rats, testicular tumors in 3, hepatic tumors in 2, abdominal lipoma in 1, leukemia in 1, ovarian tumor in 1, cystic ovaries in 5, ovarian abscesses in 2, and 1 rat each with a splenic infarct, a large abdominal hematoma, and a foot-pad granuloma. Approximately 800 tissue sections from these 250 rats were prepared for microscopic study. Histopathology attributable to D & C Red No. 10 toxicity occurred only in the spleen and bone marrow. Since survival of the test animals is considered to be more important to these animals than their slight to moderate splenic and bone marrow hyperplasia, it is apparent that D & C Red No. 10 had a beneficial effect in this experiment. However, because of the undesirable side effects of splenomegaly and bone-marrow hyperplasia at the 1% and 0.25% feeding levels, the 0.05% level should be considered the "no-effect" level. / D and C Red No. 10 (monosodium salt of 2-(2-hydroxy-1-naphthylazo)-1-naphthalenesulfonic acid)//GENOTOXICITY/ D&C No 12 tested with the Salmonella (TA1537, TA98, TA1535 and TA100)/mammalian-microsome test for mutagenicity was not mutagenic.

Probable Routes of Human Exposure	NIOSH (NOES Survey 1981-1983) has statistically estimated that 78,115 workers (10,072 of these were female) were potentially exposed to barium lithol red in the US(1).

Antidote and Emergency Treatment

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Barium and Related Compounds/Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool ... . Do not attempt to neutralize because of exothermic reaction. Cover skin burns with dry sterile dressings after decontamination ... . /Barium and Related Compounds/Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious or is in severe respiratory distress. Monitor cardiac rhythm and treat arrhythmias if necessary ... . Start IV administration of 0.9% saline (NS) or lactated Ringer's (LR) /SRP: "To keep open", minimal flow rate/. For hypotension with signs of hypovolemia, administer fluid cautiously Watch for signs of fluid overload. For hypotension with signs of hypovolemia, administer fluid cautiously. Watch for signs of fluid overload ... . Treat seizures with diazepam or lorazepam ... . Use proparacaine hydrochloride to assist eye irrigation ... . /Barium and Related Compounds/