HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(R)-1,2-Epoxypropane
(R)-2-Methyloxirane · (2R)-2-methyloxirane · (R)-PROPYLENE OXIDE · (R)-(+)-PropyL · (r)-epoxypropane · (+)-Methyloxirane · R(+)-METHYLOXIRANE · (R)-1,2-EPOXYPROPANE
Identifikatoren & physikalische Daten
| CAS No. | 15448-47-2 |
|---|---|
| Summenformel | C3H6O |
| Durchschnittliche Molmasse | 58,08 g/mol |
| Monoisotopische Masse | 58,04186481 g/mol |
| SMILES | C[C@@H]1CO1 |
| InChIKey | GOOHAUXETOMSMM-GSVOUGTGSA-N |
| PubChem CID | 146261 |
| ChEMBL | CHEMBL1901974 |
| ChEBI | CHEBI:28985 |
| EC No. | 604-958-6 |
| DTXSID | DTXSID201320388 |
Chemische & physikalische Eigenschaften
| XLogP | 0 |
|---|---|
| Polarare Oberfläche (TPSA) | 12,5 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 1 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 4 |
| Formalladung | 0 |
| Komplexität | 26,5 |
| Arzneimittel | Pharmaceuticals -> Listed in ZINC15 |
| Schmelzpunkt | -111.91°C (estimate) |
| Siedepunkt | 33-34 °C(lit.) |
| Dichte | 0.829 g/mL at 20 °C(lit.) |
| Dampfdruck | 588 hPa (20 °C) |
| Brechungsindex | n20/D 1.366(lit.) |
| Flammpunkt | -31 °F |
| Lagerbedingungen | Store at <= 20°C. |
| Löslichkeit | 405g/lMiscible with water and many organic solvents. |
| Aggregatzustand | clear liquid |
| Farbe | Colorless to Almost colorless |
| Explosionsgrenze | 1.9-37%(V) |
| Merck | 14,7856 |
| BRN | 79764 |
| InChI | 1S/C3H6O/c1-3-2-4-3/h3H,2H2,1H3/t3-/m1/s1 |
| InChIKey | GOOHAUXETOMSMM-GSVOUGTGSA-N |
| SMILES | C[C@@H]1CO1 |
| LogP (Verteilungskoeffizient) | 0.03-0.085 |
| CAS Datenbank | 15448-47-2(CAS DataBase Reference) |
Sicherheit & Vorschriften
| GHS-Einstufung | DangerH224 (100%): Extremely flammable liquid and vapor [Danger Flammable liquids]P203, P210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P280, P301+P316, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P317, P318, P319, P321, P330, P332+P317, P337+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 49 reports by companies from 9 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.H302: Harmful if swallowed [Warning Acute toxicity, oral] |
|---|---|
| Regulatorische Informationen | Chemical: Oxirane, methyl-, (R)-Status: Active Update: 28-02-2011 https://echa.europa.eu/registration-dossier/-/registered-dossier/6315(R)-(+)-1,2-Propylene oxide: HSNO Approval: HSR004105 Approved with controls |
| Weitere Sicherheitsinformationen | IMAP assessments - Methyloxirane (R-, S- and (R,S)-): Human health tier II assessment |
| Hazard Classes and Categories | Flam. Liq. 1 (100%)Acute toxicity - category 4 |
| Wassergefährdungsklasse (WGK) | 3 |
| UN-Transportnummer | UN 1280 3/PG 1 |
| Zollcode | 2910 20 00 |
| RTECS-Nr. | UJ2650000 |
| R-Sätze (R) | 12-25-2017/12/25 |
| Toxizität | LD50 orally in Rabbit: 380 mg/kg LD50 dermal Rabbit 1243 mg/kg |
| Gefahrensymbole | F+,T |
| Sicherheitshinweise (S) | 45 |
| Gefahrenklasse | 3Acute Tox. 3 DermalAcute Tox. 3 InhalationAcute Tox. 4 OralCarc. 1BEye Irrit. 2Flam. Liq. 1Muta. 1BSkin Irrit. 2STOT SE 3 |
| Verpackungsgruppe | I |
| Lagerklasse | 3 - Flammable liquids |
| Selbstentzündungstemperatur | 430 °C DIN 51794 |
Anwendungen & Verwendung
Verwenden
(R)-(+)-Propylene oxide is widely utilized in the manufacture of polyether polyols and propylene glycol, which is used to make the polyurethane plastics. It finds application as a fumigant for the sterilization of packaged foods and plastic medical instruments. Combine with ethanol, it used to make biological samples for electron microscopy. It also used in model aircraft and surface vehicles as a glow fuel.