HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Corundum
ALUMINA · ALUMINIUM OXIDE · SAPPHIRE · Aluminiumoxid · ALUMINIUM OXIDE BASIC · ALUMINIUM OXIDE NEUTRAL · RUBY · ALUNDUM
Identifikatoren & physikalische Daten
| CAS No. | 12174-49-1 |
|---|---|
| Summenformel | Al2O3 |
| Durchschnittliche Molmasse | 101,961 g/mol |
| SMILES | [O]=[Al][O][Al]=[O] |
| InChIKey | TWNQGVIAIRXVLR-UHFFFAOYSA-N |
| PubChem CID | 14769 |
| EC No. | 603-397-4 |
Chemische & physikalische Eigenschaften
| Polarare Oberfläche (TPSA) | 43,4 |
|---|---|
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 3 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 5 |
| Formalladung | 0 |
| Komplexität | 34,2 |
| Stoffklassen | Mineral Dusts -> Other Mineral Dusts |
| Siedepunkt | decomposes2980℃ [CRC10] |
| Dampfdruck | 0 mmHg (approx) |
| Physical Description | Dry PowderLarge CrystalsOdorless, white, crystalline powder[Note: Emery is an impure variety of Al2O3 which may contain small impurities of iron, magnesium & silica. Corundum is natural Al2O3. See also CAS #1302-74-5 (corundum)]Odorless, white, crystalline powder. |
| Schmelzpunkt | 2040 °C(lit.) |
| Dichte | 1.06 g/mL at 25 °C |
| Brechungsindex | 1.771 |
| Lagerbedingungen | no temp limit |
| Aggregatzustand | powder |
| Farbe | White |
| pH | 8.5-10.5 (20°C, 100g/L in H2O, slurry) |
| Löslichkeit | insoluble H2Overy slightly soluble acids, alkalies [HAW93] |
| Dielektrizitätskonstante | 4.5(Ambient) |
| InChI | 1S/2Al.3O |
| InChIKey | TWNQGVIAIRXVLR-UHFFFAOYSA-N |
| SMILES | [Al]21O[Al](O2)O1 |
| CAS Datenbank | 1302-74-5(CAS DataBase Reference) |
| EPA chemische Informationen | Corundum (Al2O3) (1302-74-5) |
Sicherheit & Vorschriften
| GHS-Einstufung | Not ClassifiedDangerH319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]P260, P261, P264, P264+P265, P270, P271, P280, P304+P340, P305+P351+P338, P319, P337+P317, P403+P233, P405, and P501 (click each P-code to see the statement) |
|---|---|
| Regulatorische Informationen | Sapphire (Al2O3) is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of Sapphire (Al2O3) are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711) |
| Gefahrenübersicht | Emery containing no asbestos and < 1% crystalline silica is not known to be toxic when exposures are kept under reasonable control. [ACGIH] |
| Hazard Classes and Categories | Not ClassifiedSerious eye damage/eye irritation - Category 2A-2B |
| Erste Hilfe | (General first aid procedures) |
| Expositionsschutz und Persönliche Schutzausrüstung | 0.3 [mg/m3] (respirable fraction), (multiplied with the material density)[German Research Foundation (DFG)] |
| Minimum Risk Level | Intermediate Oral: 1.0 mg/kg/day (L134) Chronic Oral: 1.0 mg/kg/day (L134) |
| Respirator Recommendations | Important additional information about respirator selection |
| Threshold Limit Values (TLV) | Withdrawn [2008] |
| Permissible Exposure Limit (PEL) | 15.0 [mg/m3](total dust), 5 mg/m3(respirable fraction)15 mg/m³ (total dust), 5 mg/m³ (respirable fraction)TWA 15 mg/m3 (total) TWA 5 mg/m3 (resp) See Appendix G |
| Recommended Exposure Limit (REL) | See Appendix D |
| Immediately Dangerous to Life or Health (IDLH) | N.D. |
| Treatment | EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person). Seek immediate medical advice. SKIN: should be treated immediately by rinsing the affected parts in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the person should shower and change contaminated clothing and shoes, and then must seek medical attention. INHALATION: supply fresh air. If required provide artificial respiration. |
| Zielorgane | Eyes, skin, respiratory system |
| Gesundheitliche Auswirkungen | Aluminum targets the nervous system and causes decreased nervous system performance and is associated with altered function of the blood-brain barrier. The accumulation of aluminum in the body may cause bone or brain diseases. High levels of aluminum have been linked to Alzheimer's disease. A small percentage of people are allergic to aluminium and experience contact dermatitis, digestive disorders, vomiting or other symptoms upon contact or ingestion of products containing aluminium. (L739, L740) |
| Expositionspfade | inhalation, ingestion, skin and/or eye contactOral (L739)inhalation (L739) |
| Toxizitätsübersicht | The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphorus. The decreased phosphate body burden results in osteomalacia (softening of the bones due to defective bone mineralization) and rickets. Aluminum's neurotoxicity is believed to involve several mechanisms. Changes in cytoskeletal protein functions as a results of altered phosphorylation, proteolysis, transport, and synthesis are believed to be one cause. Aluminum may induce neurobehavioral effects by affecting permeability of the blood-brain barrier, cholinergic activity, signal transduction pathways, lipid peroxidation, and impair neuronal glutamate nitric oxide-cyclic GMP pathway, as well as interfere with metabolism of essential trace elements because of similar coordination chemistries and consequent competitive interactions. It has been suggested that aluminum's interaction with estrogen receptors increases the expression of estrogen-related genes and thereby contributes to the progression of breast cancer (A235), but studies have not been able to establish a clear link between aluminum and increased risk of breast cancer (A15468). Certain aluminum salts induce immune responses by activating inflammasomes. (L739, A235, A236) |
| Signs and Symptoms | irritation eyes, skin, respiratory systemInhalating aluminum dust causes coughing and abnormal chest X-rays. A small percentage of people are allergic to aluminium and experience contact dermatitis, digestive disorders, vomiting or other symptoms upon contact or ingestion of products containing aluminium. (L739, L740) |
| Carcinogen Classification | Not listed by IARC. IARC classified aluminum production as carcinogenic to humans (Group 1), but did not implicate aluminum itself as a human carcinogen. (L135) A link between use of aluminum-containing antiperspirants and increased risk of breast cancer has been proposed (A235), but studies have not been able to establish a clear link (A15468). |
| F | 3 |
| Wassergefährdungsklasse (WGK) | - |
| TSCA-Inventar-Status | Yes |
| UN-Transportnummer | UN1993 |
| RTECS-Nr. | BD1200000 |
| R-Sätze (R) | 36/37/38 |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 26 |
| Gefahrenklasse | 3 |
| Verpackungsgruppe | II |
| Lagerklasse | 13 - Non Combustible Solids |
Anwendungen & Verwendung
Verwenden
Depending on the formulator’s needs, aluminum oxide can be used as an abrasive, or for its absorbent, anti-caking, bulking, opacifying, or viscosity-controlling properties.