Mesterolon

Mesterolone

HCID 15020
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Grundinformationen

CAS
1424-00-6
Standard-SMILES
C[C@H]1CC(=O)C[C@@H]2CC[C@H]3[C@@H]4CC[C@H](O)[C@@]4(C)CC[C@@H]3[C@]21C
InChIKey
UXYRZJKIQKRJCF-TZPFWLJSSA-N
Summenformel
C20H32O2
Durchschnittliche Molmasse
304,5 g/mol
Monoisotopische Masse
304,24023026

Namen und Bezeichner

Bevorzugter Name
Mesterolone
IUPAC
(1S,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-1,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one
Lokaler Name
Mesterolon
Englischer Name
Mesterolone
Summenformel
C20H32O2
Molmasse
304.47

Namen und Synonyme

MesteroloneAndrovironProviron1424-00-6TestiwopSH 723MesterolonaMesterolonum17beta-Hydroxy-1alpha-methyl-5alpha-androstan-3-oneSH-723Pro-VironNSC-75054
Weitere Namen anzeigen
mesterolonMESTERELONEmasterolonesh723NSC-7504NSC 75054mestoranummesteranum
0SRQ75X9I9DTXSID90878533(1S,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-1,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-oneAndrostan-3-one, 17-hydroxy-1-methyl-, (1alpha,5alpha,17beta)-NSC750541alpha-methyl-5alpha-androstan-17beta-ol-3-one(1S,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-1,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta(a)phenanthren-3-oneRefChem:389115

Datenbank-Bezeichner

CAS
1424-00-6
PubChem CID
15020
DTXSID
DTXSID90878533
ChEMBL
CHEMBL258918
ChEBI
CHEBI:135293
UNII
0SRQ75X9I9
EC Number
215-836-3
Nikkaji
J7.487J

Eigenschaften

Berechnete Struktureigenschaften

XLogP
4,1
Polarare Oberfläche (TPSA)
37,3 Ų
H-Brücken-Donoren
1
H-Brücken-Akzeptoren
2
Frei drehbare Bindungen
0
Schwere Atome
22

Experimentelle und physikochemische Eigenschaften

Melting Point204 °C
Physical DescriptionSolid

Physikochemische Eigenschaften

Schmelzpunkt
208 °C · 208 °C
Siedepunkt
420.3 · 420.3±45.0 °C(Predicted)
Dichte
1.156 g/cm3 · 1.156 g/cm3
Brechungsindex
17.6 ° · 17.6 ° (C=0.9, CHCl3)
storage temp.
2 · 2-8°C
Löslichkeit
Practically insoluble in water, sparingly soluble in acetone, in ethyl acetate and in methanol

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 5 Einträge

Warning

H302 (97.5%): Harmful if swallowed [Warning Acute toxicity, oral]；H312 (97.5%): Harmful in contact with skin [Warning Acute toxicity, dermal]；H332 (97.5%): Harmful if inhaled [Warning Acute toxicity, inhalation]

P261, P264, P270, P271, P280, P301+P317, P302+P352, P304+P340, P317, P321, P330, P362+P364, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 40 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.

Gefahrenhinweise

Regulatory Information · 2 Einträge

DEA schedule III controlled substance

Status: Active Update: 30-03-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/12497

Hazard Classes and CategoriesAcute Tox. 4 (97.5%)；Acute Tox. 4 (97.5%)；Acute Tox. 4 (97.5%)

Regulatorische Informationen

Regulatory Information · 2 Einträge

DEA schedule III controlled substance

Status: Active Update: 30-03-2020 https://echa.europa.eu/registration-dossier/-/registered-dossier/12497

Sicherheitsdaten

wgk
3
hs_code
29372900
RTECS-Nr.
BV8063400
risk_code
20/21/22-38-19-11-61-60
hazard_code
Xn,T,F
safety_code
22-24/25-36/37/39-45-53

Chemie und Industrie

Pharmakologische Informationen

ATC Code · 3 Einträge

G03BB01

G - Genito urinary system and sex hormones；G03 - Sex hormones and modulators of the genital system；G03B - Androgens；G03BB - 5-androstanon (3) derivatives；G03BB01 - Mesterolone

QG - Genito urinary system and sex hormones；QG03 - Sex hormones and modulators of the genital system；QG03B - Androgens；QG03BB - 5-androstanon (3) derivatives；QG03BB01 - Mesterolone

MeSH Pharmacological ClassificationThese compounds stimulate anabolism and inhibit catabolism. They stimulate the development of muscle mass, strength, and power.
Cellular LocationsExtracellular；Membrane
Anwendungen · 2 Einträge

BeschreibungMesterolone (Item No. 21171) is an analytical reference standard categorized as an anabolic androgenic steroid. Formulations containing mesterolone have been used in patients with low testosterone or symptoms of aging male syndrome. Mesterolone cannot be aromatized to estrogens, unlike other androgens. This compound is the active ingredient in different pharmaceutical preparations that have been used medically but have also been widely applied in sports in order to improve athlete performance. Mesterolone is regulated as a Schedule III drug in the United States. This product is intended for research and forensic applications.

VerwendenMesterolone is a synthetic androgen and a dihydrotestosterone derivative. Mesterolone is rarely used for replacement therapies due to its weak androgenic activity.

Vor- und nachgelagerte Produkte

Anbieter100 Anbieter

Shanghai Biolang Biotechnology Co., Ltd.+86-15970428662 +86-13397199602 · [email protected]
艾吉析科技（上海）有限公司17717235263 · [email protected]
合肥翰刚医药科技有限公司+8618062405514 · [email protected]
上海哲研生物科技有限公司021-18017610038 18017610038 · [email protected]
湖北金梭生物科技有限公司00123456789 · [email protected]
Ergänzende Hinweise · 1 Eintrag

DefinitionChEBI: Mesterolone is a 3-oxo-5alpha-steroid. It is a structurally altered DHT hormone possessing the addition of a methyl group at the carbon one position. This allows the hormone to survive oral ingestion by protecting it from hepatic breakdown. This is one of the only oral anabolic steroids that is not C17-alpha alkylated (C17-aa) but instead carries the added methyl group.

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