N-Nitroso-2,6-dimethylmorpholine
Grundinformationen
- CAS
1456-28-6- Standard-SMILES
CC1CN(N=O)CC(C)O1- InChIKey
DPYMAXOKJUBANR-UHFFFAOYSA-N- Summenformel
- C6H12N2O2
- Durchschnittliche Molmasse
- 144,17 g/mol
- Monoisotopische Masse
- 144,08987763
Überblick
2,6-Dimethyl-N-nitrosomorpholine (DMNM) can cause cancer according to an independent committee of scientific and health experts.
Namen und Bezeichner
- Bevorzugter Name
- N-Nitroso-2,6-dimethylmorpholine
- IUPAC
- 2,6-dimethyl-4-nitrosomorpholine
- Englischer Name
- N-nitroso-2,6-dimethylmorpholine
- Summenformel
- C6H12N2O2
- Molmasse
- 144.17
Namen und Synonyme
2,6-Dimethyl-4-nitrosomorpholineN-Nitroso-2,6-dimethylmorpholine1456-28-6Dimethylnitrosomorpholine2,6-DimethylnitrosomorpholineMorpholine, 2,6-dimethyl-4-nitroso-2,6-DIMETHYL-N-NITROSOMORPHOLINEDTXSID4021470NSC-69924652130NH3ORefChem:163953DTXCID001470
Weitere Namen anzeigen
RS RMA04157Dodemorph Impurity 10 (N-Nitroso Dodemorph Impurity 9)
DMNMNitroso-2,6-dimethylmorpholineCCRIS 263NSC 69924Morpholine, 2,6-dimethyl-N-nitroso-UNII-652130NH3O2,6-Dimethyl-N-nitroso-morpholineCHEMBL164456
Datenbank-Bezeichner
- CAS
1456-28-6- PubChem CID
- 15081
- DTXSID
DTXSID4021470- ChEMBL
CHEMBL164456- Nikkaji
- J3.367G
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 0,3
- Polarare Oberfläche (TPSA)
- 41,9 Ų
- H-Brücken-Donoren
- 0
- H-Brücken-Akzeptoren
- 4
- Frei drehbare Bindungen
- 0
- Schwere Atome
- 10
- Formalladung
- 0
- Komplexität
- 119
Experimentelle und physikochemische Eigenschaften
Chemical ClassesNitrogen Compounds -> Nitrosamines
LogP0.32
Vapor Pressure0.02 [mmHg]
Physikochemische Eigenschaften
- Siedepunkt
- 262.78 °C · 262.78°C (rough estimate)
- Dichte
- 1.1804 · 1.1804 (rough estimate)
- Brechungsindex
- 1.45 · 1.4500 (estimate)
- pka
- -5.65 · -5.65±0.60(Predicted)
- Wasserlöslichkeit
- 124 g/L · 124g/L(24 ºC)
- Henry's Law Constant
- 3.5 · 3.5×101 mol/(m3Pa) at 25℃, Mirvish et al. (1976)
- EPA chemische Informationen
- 2 · Morpholine, 2,6-dimethyl-4-nitroso- (1456-28-6)
Sicherheit und Regulatorisches
Gefahrenhinweise
Regulatory InformationHazard Traits - Carcinogenicity
Hazards Summary
Increases tumor incidence in experimental animals by various routes of exposure; [ToxPlanet: Cal/EPA: OEHHA] Causes other liver changes, chronic pulmonary edema, and ulceration of the stomach in oral lethal-dose studies of guinea pigs; [RTECS] See Nitrosamines. See N-Nitrosomorpholine.
Toxikologische Informationen
Adverse EffectsOccupational hepatotoxin - Secondary hepatotoxins: the potential for toxic effect in the occupational setting is based on cases of poisoning by human ingestion or animal experimentation.
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological ClassificationSubstances that increase the risk of NEOPLASMS in humans or animals. Both genotoxic chemicals, which affect DNA directly, and nongenotoxic chemicals, which induce neoplasms by other mechanism, are included.
Verwendung und Herstellung
UsesFormed from the nitrosation of 2,6-dimethylmorpholine (dehydration product of bis(2-hydroxypropyl)amine); Both can be found in industrial oils; Used in carcinogenesis research; [Cal/EPA: OEHHA]
Vor- und nachgelagerte Produkte
Vorgelagerte Rohstoffe
Anbieter2 Anbieter
湖北瑞玛标物科技有限公司15787879035 15787875101 · [email protected]
南京博济达医药科技有限公司18762407961 · [email protected]
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