2-Amino-2-methyl-1,3-propanediol
Grundinformationen
- CAS
115-69-5- Standard-SMILES
CC(N)(CO)CO- InChIKey
UXFQFBNBSPQBJW-UHFFFAOYSA-N- Summenformel
- C4H11NO2
- Durchschnittliche Molmasse
- 105,14 g/mol
- Monoisotopische Masse
- 105,07897859
Überblick
2-amino-2-methylpropane-1,3-diol is an aminodiol that is propane-1,3-diol substituted ny an amino and a methyl group at position 2.
Namen und Bezeichner
- Bevorzugter Name
- 2-Amino-2-methyl-1,3-propanediol
- IUPAC
- 2-amino-2-methylpropane-1,3-diol
- Englischer Name
- 2-Amino-2-methyl-1,3-propanediol
- Summenformel
- C4H11NO2
- Molmasse
- 105.14
Namen und Synonyme
2-Amino-2-methyl-1,3-propanediol115-69-52-Amino-2-methylpropane-1,3-diolAMPDAminoglycolGentimonAminomethyl propanediol1,3-Propanediol, 2-amino-2-methyl-AmmediolIsobutandiol-2-amine1,1-Di(hydroxymethyl)ethylamine2-Amino-2-methyl-1,3-propandiol
Weitere Namen anzeigen
AMPD bufferAMPD AmmediolAmmediol, AMPDButanediolaMine
CZ7BU4QZJZDTXSID7059430NSC-6364CHEBI:991RefChem:557559DTXCID8033356204-100-7Pentaerythritol dichlorohydrin
Datenbank-Bezeichner
- CAS
115-69-5- PubChem CID
- 1531
- DTXSID
DTXSID7059430- ChEBI
CHEBI:991- UNII
- CZ7BU4QZJZ
- EC Number
- 204-100-7
- Nikkaji
- J35.183K
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- -1,8
- Polarare Oberfläche (TPSA)
- 66,5 Ų
- H-Brücken-Donoren
- 3
- H-Brücken-Akzeptoren
- 3
- Frei drehbare Bindungen
- 2
- Schwere Atome
- 7
- Formalladung
- 0
- Komplexität
- 51,7
Experimentelle und physikochemische Eigenschaften
Chemical ClassesNitrogen Compounds -> Amino Alcohols, Other
Cosmetics
Cosmetic ingredients (Aminomethyl Propanediol) -> CIR (Cosmetic Ingredient Review)
Cosmetic ingredients (Aminomethylpropanediol) -> CIR (Cosmetic Ingredient Review)
Buffering
SpringerMaterials PropertiesFusion temperature
Vapor Pressure0.00654 [mmHg]
Physical Description
Large Crystals; Liquid
Solid; [Merck Index] Colorless crystalline solid; [Aldrich MSDS]
Physikochemische Eigenschaften
- Schmelzpunkt
- 100 · 100-110 °C (lit.)
- Siedepunkt
- 151 °C/10 · 151 °C/10 mmHg (lit.)
- Dichte
- 1.0509 · 1.0509 (estimate)
- Dampfdichte
- 3.63 · 3.63 (vs air)
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Danger
H315 (89%): Causes skin irritation [Warning Skin corrosion/irritation]
P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 228 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Regulatory Information
Chemical: 1,3-Propanediol, 2-amino-2-methyl-
1,3-Propanediol, 2-amino-2-methyl- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1,3-Propanediol, 2-amino-2-methyl- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)
REACH registered substance: 2-amino-2-methylpropane-1,3-diol (EC: 204-100-7)
2-Amino-2-methyl-1,3-propanediol: Does not have an individual approval but may be used under an appropriate group standard
Hazards SummaryCauses somnolence, muscle weakness, and coma in oral lethal-dose studies of rabbits; [RTECS] A skin and strong eye irritant; [Aldrich MSDS]
Hazard Classes and CategoriesSkin Irrit. 2 (89%)
Toxikologische Informationen
Adverse EffectsNeurotoxin - Other CNS neurotoxin
Toxicity Summary
Chemie und Industrie
Verwendung und Herstellung
Uses
CIR ingredient: Aminomethyl Propanediol
CIR ingredient: Aminomethylpropanediol
Used to make surfactants, vulcanization accelerators, and pharmaceuticals; Also used as a biological buffer, absorbent for acidic gases, and emulsifying agent (cosmetics, mineral oil, leather dressings, textile specialties, and cleaning compounds; Also used in hair sprays and wave sets; [Merck Index]
Leather Tanning and Processing [Category: Industry]
U.S. Production2023: 107,056 lb
Consumer UsespH regulating agent
Industry UsesStabilizing agent
Household ProductsInformation on 1 consumer products that contain Aminomethyl propanediol in the following categories is provided:
Use ClassificationCosmetics -> Buffering
General Manufacturing Information
Paint and Coating Manufacturing
1,3-Propanediol, 2-amino-2-methyl-: ACTIVE
Anwendungen
VerwendenA useful biological buffer2-Amino-2-methyl-1,3-propanediol is used to make surfactants, vulcanization accelerators and as a biological buffer. It acts as an absorbent for acidic gases and emulsifying agent for cosmetics, mineral oil, leather dressings, textile specialties and cleaning compounds. It is also used in hair sprays. It acts as a buffer for the determination of alkaline phosphatase activity and spacer in isotachophoresis of proteins. It serves as a reaction buffer for enzymes with an activity in the basic pH range such as alkaline phosphatase. Further, it is used in the preparation of 4-hydroxymethyl-4-methyl-oxazolidin-2-one.
Zugehörige Reaktionen
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