Grundinformationen
- Standard-SMILES
O=S(=O)(Cl)CCCl- InChIKey
VHCSBTPOPKFYIU-UHFFFAOYSA-N- Summenformel
- C2H4Cl2O2S
- Durchschnittliche Molmasse
- 163,02 g/mol
- Monoisotopische Masse
- 161,93090573
Überblick
Ethanesulfonyl chloride, 2-chloro- appears as a liquid. Density 1.56 g / cm3. Flash point exceeds 230 °F.
Namen und Bezeichner
- Bevorzugter Name
- Ethanesulfonylchloride, 2-chloro-
- IUPAC
- 2-chloroethanesulfonyl chloride
- Lokaler Name
- (2-Chlorethyl)sulfonylchlorid
- Englischer Name
- 2-chloroethanesulfonyl chloride
- Summenformel
- C2H4Cl2O2S
- Molmasse
- 163.02
Namen und Synonyme
Weitere Namen anzeigen
Datenbank-Bezeichner
- CAS
1622-32-8- PubChem CID
- 15385
- DTXSID
DTXSID5061825- UNII
- AET6VQ5A3Q
- EC Number
- 216-594-1
- Nikkaji
- J78.119C
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 1
- Polarare Oberfläche (TPSA)
- 42,5 Ų
- H-Brücken-Donoren
- 0
- H-Brücken-Akzeptoren
- 2
- Frei drehbare Bindungen
- 2
- Schwere Atome
- 7
- Formalladung
- 0
- Komplexität
- 121
Experimentelle und physikochemische Eigenschaften
Chemical Classes
Toxic Gases & Vapors -> Acid Halides
Reactive agents - 1st degree
Density
1.55 at 68 °F (EPA, 1998) - Denser than water; will sink
1.555 at 20 °C/4 °C
1.555 @ 20°C
Boiling Point
392 to 397 °F at 760 mmHg (EPA, 1998)
200-3 °C
Physical Description
Ethanesulfonyl chloride, 2-chloro- appears as a liquid. Density 1.56 g / cm3. Flash point exceeds 230 °F.
Liquid; [CAMEO] Colorless liquid; [MSDSonline]
Physikochemische Eigenschaften
- Schmelzpunkt
- 3 °C · 3 °C
- Siedepunkt
- 84 · 84-86 °C15 mm Hg(lit.)
- Dichte
- 1.56 g/mL · 1.56 g/mL at 25 °C(lit.)
- Dampfdruck
- 15 mm · 15 mm Hg ( 84 °C)
- Brechungsindex
- 20 · n20/D 1.493(lit.)
- Flammpunkt
- 230 °F · >230 °F
- storage temp.
- Refrigerator
- Aggregatzustand
- Liquid
- Farbe
- Clear slightly yellow to brown
- Wasserlöslichkeit
- Reacts with water.
- BRN
- 1751202 · 1751202
- InChI
- InChI=1S/C2H4Cl2O2S/c3-1-2-7(4,5)6/h1-2H2
- InChIKey
- VHCSBTPOPKFYIU-UHFFFAOYSA-N
- SMILES
- C(S(Cl)(=O)=O)CCl
- CAS Datenbank
- 1622 · 1622-32-8(CAS DataBase Reference)
- EPA chemische Informationen
- 2 · 2-Chloro-ethanesulfonyl chloride (1622-32-8)
Sicherheit und Regulatorisches
GHS-Klassifizierung
GHS Classification
Danger
H301 (97.9%): Toxic if swallowed [Danger Acute toxicity, oral]
P260, P264, P270, P271, P280, P284, P301+P316, P301+P330+P331, P302+P361+P354, P304+P340, P305+P354+P338, P316, P320, P321, P330, P363, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 47 reports by companies from 6 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Danger
H301: Toxic if swallowed [Danger Acute toxicity, oral]
Gefahrenhinweise
Hazards Summary
Reacts with water evolving hydrogen chloride; [CAMEO] Reacts violently with water; A corrosive substance that can cause injury to the skin, eyes, and respiratory tract; Inhalation may cause chemical pneumonitis; Effects in high-dose animal studies include abnormal liver function tests; [MSDSonline] See Ethanesulfonyl chloride.
Reactivity Profile
ETHANESULFONYL CHLORIDE, 2-CHLORO- is incompatible with strong oxidizing agents, alcohols, amines, alkali. May react vigorously or explosively if mixed with diisopropyl ether or other ethers in the presence of trace amounts of metal salts [J. Haz. Mat., 1981, 4, 291].
Hazard Classes and Categories
Acute Tox. 3 (97.9%)
Acute toxicity (Oral) - Category 3
Reactive agents - 1st degree
Sicherheit und Schutzausrüstung
First Aid
Signs and Symptoms of Ethanesulfonyl Chloride, 2-Chloro- Exposure: No information is available on specific clinical effects of exposure to ethanesulfonyl chloride, 2-chloro- exposure. However, because ethanesulfonyl chloride, 2-chloro- is expected to be an irritant and general toxicant, signs and symptoms of exposure may include the following: headache, dizziness, weakness, nausea, irritation of the eyes, skin, and respiratory tract, and dermatitis. Severe respiratory tract irritation can progress to pulmonary edema, the onset of which may be delayed 24-72 hours. Irritation or burns of the esophagus or gastrointestinal tract are possible.
Disposal Methods
SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.
Protective Action Criteria (PAC)
0.23 [mg/m3]
2.5 [mg/m3]
19 [mg/m3]
Personal Protective Equipment (PPE)
For emergency situations, wear a positive pressure, pressure-demand, full facepiece self-contained breathing apparatus (SCBA) or pressure- demand supplied air respirator with escape SCBA and a fully-encapsulating, chemical resistant suit. (EPA, 1998)
Toxikologische Informationen
Sicherheitsdaten
- F
- 10-19
- wgk
- 3
- tsca
- TSCA listed
- ridadr
- UN 3390 6.1/PG 1
- hs_code
- 29049090
- RTECS-Nr.
- KI8060000
- risk_code
- 22-26-34-36
- Toxizität
- mouse,LC50,inhalation,250mg/m3/4H (250mg/m3),Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 15(6), Pg. 59, 1971.
- hazard_code
- T+
- safety_code
- 26-28-36/37/39-45-23
- hazard_class
- 8
- packing_group
- II
- Giftige Stoffe Daten
- 1622-32-8(Hazardous Substances Data)
Chemie und Industrie
Verwendung und Herstellung
Anwendungen
Verwenden2-Chloroethanesulfonyl chloride was used in one-pot sulfonylation/intramolecular thia-Michael protocol for the synthesis of 1,5,2-dithiazepine 1,1-dioxides. It was also used in synthesis of vinyl sulfonamides with a furan, carbocyclic, semi cyclic or acyclic 1,3-diene moiety.
Vor- und nachgelagerte Produkte
Vorgelagerte Rohstoffe
Nachgelagerte Produkte
Anbieter50 Anbieter
Zugehörige Reaktionen
Verknüpfte Notizen
Wird geladen…