HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Fluoren-2-ylamin
2-FLUORENAMINE · 9H-FLUOREN-2-AMINE · 2-AF · 2-AminofL · Aminofluoren · 2-AMinofluor · AKOS AUF02047 · 2-Aminoflorene
Identifikatoren & physikalische Daten
| CAS No. | 153-78-6 |
|---|---|
| Summenformel | C13H11N |
| Durchschnittliche Molmasse | 181,23 g/mol |
| Monoisotopische Masse | 181,08914936 g/mol |
| SMILES | Nc1ccc2c(c1)Cc1ccccc1-2 |
| InChIKey | CFRFHWQYWJMEJN-UHFFFAOYSA-N |
| PubChem CID | 1539 |
| ChEMBL | CHEMBL84472 |
| EC No. | 205-817-8 |
| DTXSID | DTXSID1049223 |
| Lokaler Name | Fluoren-2-ylamin |
Chemische & physikalische Eigenschaften
| XLogP | 3,1 |
|---|---|
| Polarare Oberfläche (TPSA) | 26 |
| H-Brücken-Donoren | 1 |
| H-Brücken-Akzeptoren | 1 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 14 |
| Formalladung | 0 |
| Komplexität | 213 |
| Polymers | Other Classes -> Polycyclic Aromatic Hydrocarbons |
| SpringerMaterials Properties | 13C nuclear magnetic resonance spectrum |
| LogP (Verteilungskoeffizient) | 3.14 |
| Color/Form | NEEDLES FROM DIL ALCLONG PLATES FROM DIL ALCOHOL |
| Löslichkeit | less than 1 mg/mL at 67.1 °F (NTP, 1992)SOL IN ALCOHOL, ETHERestimated water solubility of 33 mg/l at 25 °Csoluble in Ether,Alcohol<0.1 g/100 mL at 19.5 ºC |
| Decomposition | When heated to decomp it emits NO(x). |
| Schmelzpunkt | 257 to 261 °F (NTP, 1992)131-132 °C124-128 °C (lit.) |
| Dampfdruck | 0.0000279 [mmHg] |
| Physical Description | 2-aminofluorene is a brown crystal powder. (NTP, 1992)Brown solid[CAMEO] Off-white powder[MSDSonline] |
| Other Experimental Properties | UV: 2-350 (Organic Electronic Spectral Data, Phillips et al, John Wiley & Sons, New York) /Fluorene, 1-amino/UV: 3-388 (Organic Electronic Spectral Data, Phillips et al, John Wiley & Sons, New York) /Fluorene, 9-amino/ |
| Siedepunkt | 304.35°C (rough estimate) |
| Dichte | 1.0941 (rough estimate) |
| Brechungsindex | 1.6118 (estimate) |
| Lagerbedingungen | Keep in dark place,Inert atmosphere,Room temperature |
| Aggregatzustand | powder to crystal |
| pKa (Säurekonstante) | 4.34±0.20(Predicted) |
| Farbe | White to Orange to Green |
| BRN | 1945861 |
| Henry-Konstante | 2.7×102 mol/(m3Pa) at 25℃, HSDB (2015) |
| InChI | InChI=1S/C13H11N/c14-11-5-6-13-10(8-11)7-9-3-1-2-4-12(9)13/h1-6,8H,7,14H2 |
| InChIKey | CFRFHWQYWJMEJN-UHFFFAOYSA-N |
| SMILES | C1C2=C(C=CC=C2)C2=C1C=C(N)C=C2 |
| CAS Datenbank | 153-78-6(CAS DataBase Reference) |
| NIST chemische Informationen | Fluoren-2-amine(153-78-6) |
| EPA chemische Informationen | 2-Aminofluorene (153-78-6) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH302 (37.5%): Harmful if swallowed [Warning Acute toxicity, oral]P203, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P317, P318, P319, P321, P330, P332+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 8 reports by companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | Hazard Traits - Carcinogenicity9H-Fluoren-2-amine: Does not have an individual approval but may be used under an appropriate group standard |
| DOT-Kennzeichnung | Poison |
| Brandgefahren | Flash point data for this material are not available, but it is probably combustible. (NTP, 1992) |
| Gesundheitsgefahren | ACUTE/CHRONIC HAZARDS: When heated to decomposition this compound emits toxic fumes. (NTP, 1992) |
| Gefahrenübersicht | Evidence for carcinogenicity in studies with rats and mice[HSDB] An irritant[MSDSonline] See POLYCYCLIC AROMATIC HYDROCARBONS. |
| Reaktive Gruppe | Amines, Aromatic |
| Reactivity Profile | 2-AMINOFLUORENE forms salts with acids and can react with oxidizing materials. (NTP, 1992) |
| Air and Water Reactions | This compound is sensitive to prolonged exposure to air. Insoluble in water. |
| Hazard Classes and Categories | Acute Tox. 4 (37.5%) |
| Brandbekämpfung | Fires involving this compound may be controlled with carbon dioxide, dry chemical, or Halon extinguishers. (NTP, 1992) |
| Erste Hilfe | EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. |
Anwendungen & Verwendung
Verwenden
PAAs are used in the rubber, textile, and dye industries. They are used as intermediates in the manufacture of plastics, drugs, and carbamate pesticides. The aromatic amines 2-aminofluorene and N-acetyl aminofluorene were being developed during the 1930s for use as pesticides; however, they were found to be carcinogenic in laboratory animals. They were never marketed as pesticides.