Grundinformationen
- Standard-SMILES
O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1ccc2cc3ccccc3cc2c1- InChIKey
ZITQUAHPZJHCJH-UHFFFAOYSA-N- Summenformel
- C29H29Cl2N3O
- Durchschnittliche Molmasse
- 506,5 g/mol
Überblick
a dopamine D3 receptor antagonist; structure in first source
Namen und Bezeichner
- Bevorzugter Name
- Ngb-2849
- IUPAC
- N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]anthracene-2-carboxamide
Namen und Synonyme
NGB284926P8N956NZNGB-2849197242-80-1RefChem:927696NGB 2849UNII-26P8N956NZN-(4-(4-(2,3-Dichlorophenyl)-1-piperazinyl)butyl)-2-anthracenecarboxamide2-Anthracenecarboxamide, N-(4-(4-(2,3-dichlorophenyl)-1-piperazinyl)butyl)-N-{4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyl}-2-anthracenecarboxamideorb1739455SCHEMBL8183795
Weitere Namen anzeigen
ZITQUAHPZJHCJH-UHFFFAOYSA-N
Datenbank-Bezeichner
- CAS
197242-80-1- PubChem CID
- 15411150
- UNII
- 26P8N956NZ
- Nikkaji
- J959.637B
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 7
- Polarare Oberfläche (TPSA)
- 35,6 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 3
- Frei drehbare Bindungen
- 7
- Schwere Atome
- 35
- Formalladung
- 0
- Komplexität
- 685
Chemie und Industrie
Pharmakologische Informationen
MeSH Pharmacological Classification
Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as ANTIEMETICS, in the treatment of Tourette syndrome, and for hiccup. Dopamine receptor blockade is associated with NEUROLEPTIC MALIGNANT SYNDROME.
Zugehörige Reaktionen
4
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