9-Fluor-11β,21-dihydroxy-16α,17-(isopropylidendioxy)pregna-1,4-dien-3,20-dion-21-acetat
Triamcinolone acetonide 21-acetate
Grundinformationen
- CAS
3870-07-3- Standard-SMILES
CC(=O)OCC(=O)[C@@]12OC(C)(C)O[C@@H]1C[C@H]1[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]12C- InChIKey
VOBDXTSTTMAKHK-VHDCPBDGSA-N- Summenformel
- C26H33FO7
- Durchschnittliche Molmasse
- 476,5 g/mol
- Monoisotopische Masse
- 476,22103155
Namen und Bezeichner
- Bevorzugter Name
- Triamcinolone acetonide 21-acetate
- IUPAC
- [2-[(1S,2S,4R,8S,9S,11S,12R,13S)-12-fluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxoethyl] acetate
- Lokaler Name
- 9-Fluor-11β,21-dihydroxy-16α,17-(isopropylidendioxy)pregna-1,4-dien-3,20-dion-21-acetat
- Englischer Name
- Triamcinolone acetonide 21-acetate
- Summenformel
- C26H33FO7
- Molmasse
- 476.54
Namen und Synonyme
Triamcinolone acetonide acetate3870-07-3TRIAMCINOLONE ACETONIDE 21-ACETATE576QLL2I1ZDTXSID20959526EINECS 223-388-5TRIAMCINOLONE ACETONIDE 21-ACETATE [MI]TRIAMCINOLONE ACETONIDE ACETATE [WHO-DD]TRIAMCINOLONE ACETONIDE IMPURITY F [EP IMPURITY]PREGNA-1,4-DIENE-3,20-DIONE, 21-(ACETYLOXY)-9-FLUORO-11-HYDROXY-16,17-((1-METHYLETHYLIDENE)BIS(OXY))-, (11.BETA.,16.ALPHA.)-PREGNA-1,4-DIENE-3,20-DIONE, 9-FLUORO-11.BETA.,16.ALPHA.,17,21-TETRAHYDROXY-, CYCLIC 16,17-ACETAL WITH ACETONE, 21-ACETATETRIAMCINOLONE ACETONIDE IMPURITY F (EP IMPURITY)
Weitere Namen anzeigen
BNKY017-TA039-fluoro-11βThannad acetate20-dione 21-acetateTriamcinolone acetonTriamcinolone Impurity FTriamcinolone impurity ITriamcinolon Acetonide acetateTriamcinolone cinolone Impurity F
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 3,1
- Polarare Oberfläche (TPSA)
- 99,1 Ų
- H-Brücken-Donoren
- 1
- H-Brücken-Akzeptoren
- 8
- Frei drehbare Bindungen
- 4
- Schwere Atome
- 34
- Formalladung
- 0
- Komplexität
- 1.030
Physikochemische Eigenschaften
- Schmelzpunkt
- 266 °C · 266 °C
- Siedepunkt
- 589.4 · 589.4±50.0 °C(Predicted)
- Dichte
- 1.31 · 1.31±0.1 g/cm3(Predicted)
- storage temp.
- Refrigerator
- Löslichkeit
- Chloroform (Slightly, Sonicated), Methanol (Slightly)
- Aggregatzustand
- Solid
- pka
- 13.1 · 13.10±0.70(Predicted)
- Farbe
- White to Off-White
- InChIKey
- VOBDXTSTTMAKHK-AJGDGBNYNA-N
- SMILES
- C([C@@]12OC(C)(C)O[C@]1([H])C[C@@]1([H])[C@]3([H])CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]21C)(=O)COC(=O)C |&1:1,7,10,12,22,24,26,29,r|
- CAS Datenbank
- 3870 · 3870-07-3
Sicherheit und Regulatorisches
GHS-Klassifizierung
GHS Classification
Warning
H361 (100%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]
P203, P280, P318, P405, and P501 (click each P-code to see the statement)
The GHS information provided by 1 company from 1 notification to the ECHA C&L Inventory.
Gefahrenhinweise
Regulatory InformationREACH registered substance: 9-fluoro-11β,21-dihydroxy-16α,17-(isopropylidenedioxy)pregna-1,4-diene-3,20-dione 21-acetate (EC: 223-388-5)
Hazard Classes and CategoriesRepr. 2 (100%)
Sicherheitsdaten
- hs_code
- 29147000
- safety_code
- 24/25
Chemie und Industrie
Anwendungen
VerwendenTriamcinolone acetonide 21-acetate is derivative of Triamcinolone Acetonide, a glucocorticoid, antiasthmatic (inhalant).It also can be used for eczema and dermatitis and is currently a long-acting glucocorticoid drug widely applied in the dermatology clinical application of China.
Vor- und nachgelagerte Produkte
Vorgelagerte Rohstoffe
Anbieter100 Anbieter
HubeiwidelychemicaltechnologyCo.,Ltd18627774460 · [email protected]
山东雨禾医药科技有限公司15263077727
湖北金梭生物科技有限公司00123456789 · [email protected]
Hebei shuoxi biotechnology co. LTD+8613081092107
湖北研科时代科技有限公司15780669880 · [email protected]
Baoji Guokang Healthchem co.,ltd
Zugehörige Reaktionen
0
Keine Reaktionsaufzeichnungen unter den aktuellen Filterkriterien.
Notizen zur Verbindung
Wird geladen…