HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Tolmetin glucuronide
Tolmetin USP/EP/BP · tolmetin glucuronide · Tolmetin -D-Glucuronide · Tolmetin β-D-Glucuronide · Tolmetin-Beta-D-Glucuronide · Tolmetin Sodium Impurity 147 · Tolmetin acyl-β-D-glucuronide · TolMetin-acyl-beta-D-Glucuronide
Identifikatoren & physikalische Daten
| CAS No. | 71595-19-2 |
|---|---|
| Summenformel | C21H23NO9 |
| Durchschnittliche Molmasse | 433,413 g/mol |
| Monoisotopische Masse | 433,13728132 g/mol |
| SMILES | Cc1ccc(C(=O)c2ccc(CC(=O)O[C@@H]3O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]3O)n2C)cc1 |
| InChIKey | MEFIGCPEYJZFFC-ZFORQUDYSA-N |
| PubChem CID | 155656 |
| ChEBI | CHEBI:168766 |
| DTXSID | DTXSID50221824 |
Chemische & physikalische Eigenschaften
| Schmelzpunkt | 139-142°C |
|---|---|
| Siedepunkt | 706.1±60.0 °C(Predicted) |
| Dichte | 1.50±0.1 g/cm3(Predicted) |
| Lagerbedingungen | -20°C Freezer, Under Inert Atmosphere |
| Löslichkeit | DMSO (Slightly), Methanol (Slightly, Heated) |
| Aggregatzustand | Solid |
| pKa (Säurekonstante) | 2.68±0.70(Predicted) |
| Farbe | White to Brown |
| Stabilität | Hygroscopic |
Sicherheit & Vorschriften
| Alarmwort | Warnung |
|---|---|
| Gefahrenhinweise | Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code H315 |
Anwendungen & Verwendung
Beschreibung
Tolmetin β-D-glucuronide is a major phase II metabolite of tolmetin . Tolmetin β-D-glucuronide has been classified into a ‘warning’ category in terms of its potential to cause idiosyncratic drug toxicity, based on its half-life in several in vitro systems.