HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
5,6,7,8-Tetrahydropteridine
Tetrahydropteridine · Pteridine, 5,6,7,8-tetrahydro- · Pteridine, 5,6,7,8-tetrahydro- (6CI,7CI,8CI,9CI)
Identifikatoren & physikalische Daten
| CAS No. | 10593-78-9 |
|---|---|
| Summenformel | C6H8N4 |
| Durchschnittliche Molmasse | 136,15 g/mol |
| Monoisotopische Masse | 136,07489627 g/mol |
| SMILES | c1ncc2c(n1)NCCN2 |
| InChIKey | IDAICLIJTRXNER-UHFFFAOYSA-N |
| PubChem CID | 156 |
| ChEBI | CHEBI:28889 |
| EC No. | 196-846-4 |
| DTXSID | DTXSID00147429 |
Chemische & physikalische Eigenschaften
| XLogP | 0,3 |
|---|---|
| Polarare Oberfläche (TPSA) | 49,8 |
| H-Brücken-Donoren | 2 |
| H-Brücken-Akzeptoren | 4 |
| Frei drehbare Bindungen | 0 |
| Schwere Atome | 10 |
| Formalladung | 0 |
| Komplexität | 116 |
| Physical Description | Solid |
| Schmelzpunkt | 146-147 °C |
| Siedepunkt | 340.4±31.0 °C(Predicted) |
| Dichte | 1.186±0.06 g/cm3(Predicted) |
| pKa (Säurekonstante) | 6.60±0.10(Predicted) |
Anwendungen & Verwendung
Verwenden
With stoichiometric amounts of the tetrahydropteridine, the initial rate of tyrosine formation is independent of both the sheep-liver enzyme and TPNH, a fact that makes it unlikely that either of these components is directly involved in the hydroxylation reaction.A putative cellular function of tetrahydropteridines was investigated in Dictyostelium discoideum Ax2 using a mutant disrupted in the gene encoding sepiapterin reductase.