Atazanavir Sulfate
Daten werden ergänzt – lade die Seite später neu, um den aktuellen Stand zu sehen
Grundinformationen
- CAS
229975-97-7- Standard-SMILES
COC(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)[C@@H](O)CN(Cc1ccc(-c2ccccn2)cc1)NC(=O)[C@@H](NC(=O)OC)C(C)(C)C)C(C)(C)C.O=S(=O)(O)O- InChIKey
DQSGVVGOPRWTKI-QVFAWCHISA-N- Summenformel
- C38H54N6O11S
- Durchschnittliche Molmasse
- 802,9 g/mol
- Monoisotopische Masse
- 802,35712773
Namen und Bezeichner
- Bevorzugter Name
- Atazanavir Sulfate
- IUPAC
- methyl N-[(2S)-1-[2-[(2S,3S)-2-hydroxy-3-[[(2S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoyl]amino]-4-phenylbutyl]-2-[(4-pyridin-2-ylphenyl)methyl]hydrazinyl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate;sulfuric acid
Namen und Synonyme
Atazanavir sulfate229975-97-7Atazanavir sulphateBMS-232632-05AtazorAtazanavir so4Atazanaviri sulfas4MT4VIE29PNSC-742546EVOTAZ COMPONENT ATAZANAVIR SULFATE2,5,6,10,13-Pentaazatetradecanedioic acid, 3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-((4-(2-pyridinyl)phenyl)methyl)-, dimethyl ester, (3S,8S,9S,12S)-, sulfate (1:1) (salt)DTXSID401017206
Weitere Namen anzeigen
232632, BMSCHEBI:312432,5,6,10,13-Pentaazatetradecanedioic acid, 3,12-bis(1,1-dimethylethyl)-8-hydroxy-4,11-dioxo-9-(phenylmethyl)-6-[[4-(2-pyridinyl)phenyl]methyl]-, dimethyl ester, (3S,8S,9S,12S)-, sulfate (1:1) (salt)RefChem:54331DTXCID801475397CGP73547CGP75176CGP75355
Datenbank-Bezeichner
- CAS
229975-97-7- PubChem CID
- 158550
- DTXSID
DTXSID401017206- ChEMBL
CHEMBL1200678- UNII
- 4MT4VIE29P
- EC Number
Eigenschaften
Berechnete StruktureigenschaftenWird ergänzt
- Polarare Oberfläche (TPSA)
- 254 Ų
- H-Brücken-Donoren
- 7
- H-Brücken-Akzeptoren
- 13
- Frei drehbare Bindungen
- 18
- Schwere Atome
- 56
- Formalladung
- 0
- Komplexität
- 1.190
Sicherheit und Regulatorisches
Sicherheitsangaben dienen nur zur Orientierung und ersetzen weder das Sicherheitsdatenblatt (SDB) des Lieferanten noch geltende Vorschriften oder eine fachliche Bewertung.
GHS-Klassifizierung
GHS Classification
Danger
H302 (11.1%): Harmful if swallowed [Warning Acute toxicity, oral]；H315 (11.1%): Causes skin irritation [Warning Skin corrosion/irritation]；H318 (77.8%): Causes serious eye damage [Danger Serious eye damage/eye irritation]；H319 (22.2%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]；H335 (11.1%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]；H372 (55.6%): Causes damage to organs through prolonged or repeated exposure [Danger Specific target organ toxicity, repeated exposure]；H411 (22.2%): Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]
P260, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P305+P354+P338, P317, P319, P321, P330, P332+P317, P337+P317, P362+P364, P391, P403+P233, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 9 reports by companies from 8 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.；Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown. For more detailed information, please visit ECHA C&L website.
Gefahrenhinweise
Hazard Classes and CategoriesEye Dam. 1 (77.8%)；Eye Irrit. 2 (22.2%)；STOT RE 1 (55.6%)；Aquatic Chronic 2 (22.2%)
Toxikologische Informationen
Drug Induced Liver Injury
Drug Induced Liver Injury Rank (DILIrank 2.0)
Chemie und Industrie
Pharmakologische Informationen
FDA Pharmacological Classification
ATAZANAVIR SULFATE
HIV Protease Inhibitors [MoA]; Cytochrome P450 2C8 Inhibitors [MoA]; UDP Glucuronosyltransferases Inhibitors [MoA]; Protease Inhibitor [EPC]; Cytochrome P450 3A Inhibitors [MoA]; Cytochrome P450 3A4 Inhibitors [MoA]; UGT1A1 Inhibitors [MoA]
MeSH Pharmacological ClassificationInhibitors of HIV PROTEASE, an enzyme required for production of proteins needed for viral assembly.
Anbieter17 Anbieter
上海阿拉丁生化科技股份有限公司400-6206333 13167063860 · [email protected]
南京云志欣合生物科技有限公司18115209001 · [email protected]
湖北海克斯生化有限公司17362916295; 17362916295 · [email protected]
湖北辰心化工有限公司18696113233 · [email protected]
大连美仑生物技术有限公司0411-62910999 13889544652 · [email protected]
常州康特医药技术有限公司0519-82813797 18994752886 · [email protected]
南京生利德生物科技有限公司025-57798810 18652991625 · [email protected]
泰州同新生物医药科技有限公司0523-86818997 18652728585 · [email protected]
上海鑫圭生物科技有限公司15121041756 · [email protected]
Zugehörige Reaktionen
7
Notizen zur Verbindung
Wird geladen…