Grundinformationen
- CAS
464-49-3- Standard-SMILES
CC1(C)[C@@H]2CC[C@@]1(C)C(=O)C2- InChIKey
DSSYKIVIOFKYAU-XCBNKYQSSA-N- Summenformel
- C10H16O
- Durchschnittliche Molmasse
- 152,23 g/mol
- Monoisotopische Masse
- 152,12011513
Überblick
D-camphor appears as colorless or white crystals. Sublimes. Flash point 149 °F. Burns readily with a bright, smoky flame. Penetrating aromatic odor. Pungent, aromatic taste followed by a sensation of cold. (NTP, 1992)
Namen und Bezeichner
- Bevorzugter Name
- D-Camphor
- IUPAC
- (1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one
- Lokaler Name
- (+)-Bornan-2-on
- Englischer Name
- D-CAMPHOR
- Summenformel
- C10H16O
- Molmasse
- 152.23
Namen und Synonyme
D-CAMPHOR(1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one(R)-(+)-Camphor(R)-Camphor(1R)-(+)-CamphorD-(+)-CamphorAlcanforJapanese camphord-2-CamphanoneFormosa camphorCamphor, (+)-Camphor USP
Weitere Namen anzeigen
Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (1R)-d-camphreFEMA 2230CAMPHOR POWDER DAB 87,7-trimethyl-(1r)-bicyclo(2.2.1)heptan-2-on(1R)-1,7,7-TRIMETHYLBICYCLO[2.2.1]HEPTAN-2-ONE
d-2-BornanoneDTXSID4024721Camphor, (1R,4R)-(+)-(1R,4R)-(+)-CAMPHORDTXCID804721CHEBI:15396(1R,4R)-1,7,7-Trimethylbicyclo(2.2.1)heptan-2-oneRefChem:1082868
Datenbank-Bezeichner
- CAS
464-49-3、76-22-2- PubChem CID
- 159055
- DTXSID
DTXSID4024721- ChEBI
CHEBI:15396- UNII
- 5TJD82A1ET、N20HL7Q941
Eigenschaften
Berechnete Struktureigenschaften
- XLogP
- 2,2
- Polarare Oberfläche (TPSA)
- 17,1 Ų
- H-Brücken-Donoren
- 0
- H-Brücken-Akzeptoren
- 1
- Frei drehbare Bindungen
- 0
- Schwere Atome
- 11
- Formalladung
- 0
- Komplexität
- 217
Experimentelle und physikochemische Eigenschaften
Chemical ClassesBiological Agents -> Plant Oils and Extracts
DrugsPharmaceuticals -> Listed in ZINC15
CosmeticsDenaturant; Plasticiser
FragrancesFragrance Ingredient (d-Camphor) -> IFRA transparency List
LogP2.380
Food AdditivesCOLOR OR COLORING ADJUNCT, FLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT -> FDA Substance added to food
Density0.992 at 77 °F (NTP, 1992) - Less dense than water; will float
Flavoring AgentsEU Flavoring substances
Solubility
less than 1 mg/mL at 59 °F (NTP, 1992)
1600 mg/L @ 25 °C (exp)
Soluble in oils, water
Soluble (in ethanol)
Flash Point148 °F (NTP, 1992)
Sicherheit und Regulatorisches
GHS-Klassifizierung
GHS Classification
This chemical does not meet GHS hazard criteria for < 0.1% (1 of 1847) of reports.
Danger
H228 (99.7%): Flammable solid [Danger Flammable solids]
P210, P240, P241, P260, P261, P264, P270, P271, P280, P301+P317, P304+P340, P308+P316, P317, P330, P370+P378, P405, and P501 (click each P-code to see the statement)
Aggregated GHS information provided per 1847 reports by companies from 38 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.
Gefahrenhinweise
Regulatory Information
Chemical: Bicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (1R)-
Regulation (EC) No 1831/2003 (amended)
Status: Active Update: 10-11-2022 https://echa.europa.eu/registration-dossier/-/registered-dossier/24627
DOT LabelFlammable Solid
Fire Hazards
This chemical is combustible. (NTP, 1992)
· Flammable/combustible material.
Health Hazards
SYMPTOMS: Symptoms of exposure to this compound include irritation of the skin, eyes and mucous membranes. High concentrations may cause extreme destruction of tissue of the mucous membranes and upper respiratory tract, eyes and skin. Other symptoms of exposure include nausea, vomiting and epileptiform convulsions. It may cause colic, disturbed vision, delirium and death due to respiratory failure. It may also cause diarrhea, excitement and irrational behavior. Exposure may lead to headache, dizziness, feeling of warmth, muscle twitching, difficulty breathing, anuria, central nervous system depression and coma. Exposure may also lead to convulsions, burning sensation, coughing, wheezing, laryngitis, shortness of breath, vertigo and mental confusion. Ingestion of this compound may cause burning in the mouth and throat, epigastric pain, thirst, feeling of tension, rigidity, rapid pulse, slow respiration, twitching of the facial muscles, muscular spasms and unconsciousness. Flickering, darkening or veiling of the vision may occur, with noises in the ears and weakness. Several cases of superficial keratitis with temporary loss of corneal epithelium have been reported.
Chemie und Industrie
Pharmakologische Informationen
Metabolism/Metabolites(+)-Camphor has known human metabolites that include 5-exo-hydroxycamphor and 8-hydroxycamphor.
Cellular LocationsMembrane
Verwendung und Herstellung
Uses
Naturally occurring form of camphor; Used in organic synthesis and as an odorant, flavoring agent, moth repellent, preservative, and plasticizer in cosmetics; Also used as a topical analgesic and antipruritic; [Merck Index] Used primarily in medicaments; Used industrially as a plasticizer for cellulose esters and ethers, to make plastics, and as a solvent in cosmetics; [NTP - Final Report on Developmental Toxicity] Used as a coloring agent, flavor enhancer, and flavoring agent or adjuvant; [FDA] A major constituent of pine oil; Used as a plasticizer for cellulose nitrate, explosives, and lacquers, to make incense, in varnishes, odorants, embalming fluids, pyrotechnics, insecticides, insect repellents, and for moth and mildew proofing; [NTP]
Painting (Pigments, Binders, and Biocides) [Category: Paint]
Household ProductsInformation on 10 consumer products that contain D-Camphor in the following categories is provided:
Use Classification
Fragrance Ingredients
Flavoring Agents -> JECFA Flavorings Index
Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes
Cosmetics -> Denaturant; Plasticiser
General Manufacturing InformationBicyclo[2.2.1]heptan-2-one, 1,7,7-trimethyl-, (1R,4R)-: ACTIVE
Anwendungen
OccurrenceFrequently occurring in nature as the d- or l-form; the optically inactive form is seldom encountered. The d-form has been reported found in Cinnamomum camphora Ness. (Laurus camphora L.) from China, Japan and the East Indies; in Sassafras officinale, Lavandula spica and in other Labiatae. The l-form is reported found in the essential oils of Salvia grandiflora, Matricaria parthenium, Artemisia herba alba; the optically inactive form is found in Chrysanthemum japonicum sinense. Also reported found in orange peel oil, lemon peel oil, apricot, raspberry, anise, cinnamon root bark, ginger, pepper, coriander, calamus, sweet fennel and rosemary.
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