HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
8-Azidoadenosine
177323 · 8-N3-ADO · 8-azido-adenosin · 8-AZIDOADENOSINE · 8-AZIDO-D-ADENOSINE · Adenosine, 8-azido- · Adenosine Impurity 48 · 8-AZIDOADENOSINE ISO 9001：2015 REACH
Identifikatoren & physikalische Daten
| CAS No. | 4372-67-2 |
|---|---|
| Summenformel | C10H12N8O4 |
| Durchschnittliche Molmasse | 308,258 g/mol |
| Monoisotopische Masse | 308,09815086 g/mol |
| SMILES | [N-]=[N+]=Nc1nc2c(N)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O |
| InChIKey | KYJLJOJCMUFWDY-UUOKFMHZSA-N |
| PubChem CID | 160751 |
| DTXSID | DTXSID401351480 |
Chemische & physikalische Eigenschaften
| Schmelzpunkt | >200C (dec.) |
|---|---|
| Lagerbedingungen | Amber Vial, Refrigerator, Under Inert Atmosphere |
| Löslichkeit | DMSO (Sparingly), Methanol (Slightly), Water (Slightly) |
| Aggregatzustand | Solid |
| pKa (Säurekonstante) | 12.875±0.70(predicted) |
| Farbe | White to Light Purple |
| Stabilität | Light Sensitive, Moisture Sensitive |
Sicherheit & Vorschriften
| Zollcode | 29389090 |
|---|
Anwendungen & Verwendung
Verwenden
One compound, 8-azidoadenosine, inhibits CDP reduction in cytosolic extracts from cancer cells. 8-Azidoadenosine is an adenosine analogue conjugated with an azido group which can be used for oligonucleotide labelling. The azido group reacts with a terminal alkyne via a click reaction, forming the labelled nucleotide containing a triazole linker.