Nocardamine
Daten werden ergänzt – lade die Seite später neu, um den aktuellen Stand zu sehen
Grundinformationen
- CAS
26605-16-3- Standard-SMILES
O=C1CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN1- InChIKey
NHKCCADZVLTPPO-UHFFFAOYSA-N- Summenformel
- C27H48N6O9
- Durchschnittliche Molmasse
- 600,714 g/mol
- Monoisotopische Masse
- 600,34827712
Namen und Bezeichner
- Bevorzugter Name
- Nocardamine
- IUPAC
- 1,12,23-Trihydroxy-1,6,12,17,23,28-hexaazacyclotritriacontane-2,5,13,16,24,27-hexone
- Englischer Name
- Nocardamine
- Summenformel
- C27H48N6O9
- Molmasse
- 600.7
Namen und Synonyme
deferrioxamine ENocardaminNocardaminePROFERRIOXAMIN EDesferrioxamine EDesferri-ferrioxamine ENocardamine (Deferrioxamine E)Nocardamine (Deferrioxamine E), Antibiotic agent1,12,23-Trihydroxy-1,6,12,17,23,28-hexaazacyclotritriacontane-2,5,13,16,24,27-hexone6,17,28-Trihydroxy-1,6,12,17,23,28-hexaazacyclotritriacontane-2,5,13,16,24,27-hexaone
Datenbank-Bezeichner
- CAS
26605-16-3- PubChem CID
- 161532
- DTXSID
DTXSID00181161- ChEMBL
CHEMBL505734- ChEBI
CHEBI:50437- UNII
- Q645668975
- Nikkaji
- J34.318H
Eigenschaften
Physikochemische Eigenschaften
- Schmelzpunkt
- 192 · 192-195°
- Dichte
- 1.162 · 1.162±0.06 g/cm3(Predicted)
- storage temp.
- -20 °C · -20°C
- Löslichkeit
- Soluble in DMSO (5 mg/ml)
- Aggregatzustand
- solid
- pka
- 8 · 8+-.0.20(Predicted)
- Farbe
- Off-white
- Stabilität
- 2 years · Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
Chemie und Industrie
Anwendungen
BeschreibungNocardamine is a ferrioxamine siderophore that has been found in Streptomyces and has diverse biological activities. It chelates iron in a chrome azurol S assay (IC50 = 9.9 μM). Nocardamine inhibits M. smegmatis and M. bovis biofilm formation (MIC = 10 μM for both), an effect that can be reversed by iron. It is cytotoxic to T47D, SK-MEL-5, SK-MEL-28, and RPMI-7951 cancer cells (IC50s = 6, 18, 12, and 14 μM, respectively). Nocardamine also induces morphological changes in BM-N4 insect cells.
VerwendenNocardamine is a cyclic siderophore.
Anbieter15 Anbieter
Dayang Chem (Hangzhou) Co.,Ltd.+86-0571-88938639 17705817739 · [email protected]
Aladdin Scientific[email protected]
安耐吉化学&3A（安徽泽升科技有限公司）021-58432009 400-005-6266 · [email protected]
United Life Science020-82099279 18988968278 · [email protected]
上海陶术生物科技股份有限公司+1-781-999-5354; +1-00000000000 · [email protected]
BOC Sciences16314854226; +8616314854226 · [email protected]
浙江珲达生物科技有限公司0571-89903022 18679456698 · [email protected]
南通全益生物科技有限公司0513-66337626 18051384581 · [email protected]
上海一飞生物科技有限公司021-65675885 18964387627 · [email protected]
Zugehörige Reaktionen
1
Notizen zur Verbindung
Wird geladen…