4-Phenyl-4-piperidinocyclohexanol
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Grundinformationen
- CAS
60756-83-4- Standard-SMILES
OC1CCC(c2ccccc2)(N2CCCCC2)CC1- InChIKey
KPRUAZBLIREHPD-UHFFFAOYSA-N- Summenformel
- C17H25NO
- Durchschnittliche Molmasse
- 259,393 g/mol
- Monoisotopische Masse
- 259,19361442
Namen und Bezeichner
- Bevorzugter Name
- 4-Phenyl-4-piperidinocyclohexanol
- IUPAC
- 4-Phenyl-4-(piperidin-1-yl)cyclohexan-1-ol
- Englischer Name
- (trans)-4-PPC
- Summenformel
- C17H25NO
- Molmasse
- 259.39
Namen und Synonyme
(trans)-4-PPCKPRUAZBLIREHPD-QAQDUYKDSA-Nac trans-4’-Hydroxy Phencyclidinerac trans-4'-Hydroxy Phencyclidinetrans-4-Phenyl-4-piperidinocyclohexanol4-Phenyl-4-(piperidin-1-yl)cyclohexan-1-ol2H5]-trans-4-Phenyl-4-piperidinocyclohexanoltrans-4-Phenyl-4-(1-piperidinyl)cyclohexanoltrans-1-(1-Phenyl-4-hydroxycyclohexyl)piperidinerac trans-4-Phenyl-4-(1-piperidinyl)cyclohexanol
Datenbank-Bezeichner
- CAS
60756-83-4、78165-06-7、78165-07-8- PubChem CID
- 162171
- DTXSID
DTXSID60209577- ChEMBL
CHEMBL266562、CHEMBL273446- ChEBI
CHEBI:183505- UNII
- TAJ3PEY6RN
- Nikkaji
- J1.002.574E、J390.379F、J438.408C
Eigenschaften
Physikochemische Eigenschaften
- Siedepunkt
- 382.5 · 382.5±42.0 °C(Predicted)
- Dichte
- 1.093 · 1.093±0.06 g/cm3(Predicted)
- Löslichkeit
- 5 mg/ml; · DMF: 5 mg/ml; DMSO: 5 mg/ml; Ethanol: 10 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
- Aggregatzustand
- A crystalline solid
- pka
- 15.1 · 15.10±0.40(Predicted)
Chemie und Industrie
Anwendungen
Beschreibungtrans-4-phenyl-4-Piperidinocyclohexanol (Item No. 20565) is an analytical reference standard that is structurally categorized as an arylcyclohexylamine. It is a metabolite of phencyclidine (PCP; ). trans-4-phenyl-4-Piperidinocyclohexanol inhibits dopamine uptake in rat striatal synaptosomes to a similar extent as PCP. This product is intended for research and forensic applications.
Verwendentrans-4-Phenyl-4-(1-piperidinyl)cyclohexanol [(trans)-4-PPC] is the trans-isomer of the 4-hydroxy(cyclo) metabolite of Phencyclidine (P295502). Studies show that (trans)-4-PPC elicits dose-related increases in locomotor activity and rearing in mice, and (trans)-4-PPC may also be involved in psychotomimetic effects of PCP due to its inhibitory effect on DA uptake.
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