HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
3-Brombiphenyl
3-Bromo-1,1'-biphenyl · pbb 2 · PBB NO 2 · 218-304-9 · 3-BROMOBIPHNYL · 3-bromo-bipheny · m-Bromobiphenyl · 3-BROMOBIPHENYL
Identifikatoren & physikalische Daten
| CAS No. | 2113-57-7 |
|---|---|
| Summenformel | C12H9Br |
| Durchschnittliche Molmasse | 233,1 g/mol |
| Monoisotopische Masse | 231,98876239 g/mol |
| SMILES | Brc1cccc(-c2ccccc2)c1 |
| InChIKey | USYQKCQEVBFJRP-UHFFFAOYSA-N |
| PubChem CID | 16449 |
| ChEMBL | CHEMBL1899525 |
| EC No. | 218-304-9 |
| DTXSID | DTXSID5024639 |
| Lokaler Name | 3-Brombiphenyl |
Chemische & physikalische Eigenschaften
| XLogP | 4,6 |
|---|---|
| Polarare Oberfläche (TPSA) | 0 |
| H-Brücken-Donoren | 0 |
| H-Brücken-Akzeptoren | 0 |
| Frei drehbare Bindungen | 1 |
| Schwere Atome | 13 |
| Formalladung | 0 |
| Komplexität | 149 |
| SpringerMaterials Properties | 13C nuclear magnetic resonance spectrum |
| LogP (Verteilungskoeffizient) | 4.85 |
| Löslichkeit | Insoluble (NTP, 1992)Chloroform (Soluble), DMSO (Slightly) |
| Siedepunkt | 570 to 574 °F at 760 mmHg (NTP, 1992)300 °C |
| Physical Description | 3-bromobiphenyl is a clear yellow viscous liquid. Insoluble in water. (NTP, 1992) |
| Schmelzpunkt | 93-94 °C |
| Dichte | 1.398 g/mL at 25 °C(lit.) |
| Brechungsindex | 1.637-1.641 |
| Flammpunkt | 110 °C |
| Lagerbedingungen | Keep in dark place,Sealed in dry,Room Temperature |
| Aggregatzustand | Liquid |
| Farbe | Light yellow to gray-beige |
| Merck | 14,4188 |
| BRN | 2043191 |
| InChIKey | USYQKCQEVBFJRP-UHFFFAOYSA-N |
| CAS Datenbank | 2113-57-7(CAS DataBase Reference) |
| NIST chemische Informationen | 1,1'-Biphenyl, 3-bromo-(2113-57-7) |
| EPA chemische Informationen | 3-Bromobiphenyl (2113-57-7) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 40 reports by companies from 3 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | S - indicates a substance that is identified in a final Significant New Use Rule.Restricted substance: 3-bromobiphenyl |
| Brandgefahren | Flash point data for this chemical are not available. It is probably combustible. (NTP, 1992) |
| Reaktive Gruppe | Aryl Halides |
| Reactivity Profile | 3-BROMOBIPHENYL may be sensitive to light. This compound may react with oxidizing materials. (NTP, 1992) |
| Air and Water Reactions | Insoluble in water. |
| Hazard Classes and Categories | Skin Irrit. 2 (100%) |
| Brandbekämpfung | Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. (NTP, 1992) |
| Erste Hilfe | EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop. |
| Freisetung ohne Brand | SMALL SPILLS AND LEAKAGE: If you spill this chemical, FIRST REMOVE ALL SOURCES OF IGNITION. Then, use absorbent paper to pick up all liquid spill material. Your contaminated clothing and absorbent paper should be sealed in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned. |
| Minimum Risk Level | Acute Oral: 0.01 mg/kg/day (L134) |
| Personal Protective Equipment (PPE) | RECOMMENDED RESPIRATOR: Where the neat test chemical is weighed and diluted, wear a NIOSH-approved half face respirator equipped with an organic vapor/acid gas cartridge (specific for organic vapors, HCl, acid gas and SO2) with a dust/mist filter. (NTP, 1992) |
| Treatment | EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person). Seek immediate medical advice. SKIN: should be treated immediately by rinsing the affected parts in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the person should shower and change contaminated clothing and shoes, and then must seek medical attention. INHALATION: supply fresh air. If required provide artificial respiration. |
| Gesundheitliche Auswirkungen | PBB exposure may cause weight loss, skin disorders (such as acne), nervous and immune systems effects, and effects on the liver, kidneys, and thyroid gland. (L628) |
| Expositionspfade | Oral (L628)inhalation (L628)dermal (L628) |
| Toxizitätsübersicht | The exact mechanism of toxicty of PBBs varies depending on the specific congener. The predominant interaction is believed to involve the aryl hydrocarbon receptor (AhR). PBBs bind to and activate the AhR, which in turn initiates the transcriptional upregulation of a number of genes, affecting biochemical and endocrine pathways, cell cycle regulation, morphogenesis, oxidative stress response, and various other processes. This results in the numerous toxic responses characteristic of PBBs. Some of the known induced genes include the cytochrome P-450-dependent monooxygenases CYP1A1 and CYP1A2. (L628) |
| Signs and Symptoms | Symptoms of PBB exposure may include nausea, abdominal pain, loss of appetite, joint pain, fatigue, and weakness. (L629) |
| Carcinogen Classification | 2A, probably carcinogenic to humans. (L135) |
| Wassergefährdungsklasse (WGK) | 3 |
| TSCA-Inventar-Status | TSCA listed |
| Zollcode | 29039990 |
| RTECS-Nr. | DV1750000 |
| R-Sätze (R) | 36/37/38 |
| Toxizität | mouse,LDLo,intraperitoneal,500mg/kg (500mg/kg),"Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. Vol. 6, Pg. 217, 1954. |
| Gefahrensymbole | Xi |
| Sicherheitshinweise (S) | 37/39-26-36 |
Anwendungen & Verwendung
Verwenden
3-Bromobiphenyl is utilized as an electrochemical immunosensor based on poly(dopamine) coated gold nanocluster for brominated flame retardants.