Dichlorisocyanursäure

Other Uses -> Biocides/Disinfectants

Reactive agents - 2nd degree

White, crystalline powder, granules

White crystals

Insoluble (<1 mg/ml at 81 °F) (NTP, 1992)

Readily soluble in polar organic solvents (ketones, nitriles, esters)

Moderately soluble in water

Aqueous solubility = 0.7% at 20 °C

437 °F (NTP, 1992)

226.6 °C

FCS -> FDA Cumulative Estimated Daily Intake (CEDI)

FCS -> FDA Inventory of Food Contact Substances Listed in 21 CFR

Dichloroisocyanuric acid, solid is a white crystalline solid with an odor of chlorine. The material itself is noncombustible but if contaminated with a combustible material ignition can result. It will accelerate the burning of combustible materials. Contact with ammonium compounds or hydrated salts can cause a very vigorous chemical reaction. It may vigorously react with small quantities of water releasing chlorine gas. Prolonged exposure to fire or heat of the material may result in the vigorous decomposition of the material and the rupturing of its containers. Material containing less than 39 percent available chlorine will undergo reactions as described above though it may be longer to initiate and the resulting reaction may not be as vigorous. It is used as a dry bleach in household cleaning compounds and swimming pool disinfectants.

Wet Solid

White solid; Slightly hygroscopic; [Hawley] Strong odor of chlorine; [HSDB]

When heated to decomposition it emits chlorides and carbon monoxide.

Slightly hygroscopic; oxidizer, may ignite organic materials on contact.

Danger

H272: May intensify fire; oxidizer [Danger Oxidizing liquids; Oxidizing solids]

P210, P220, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P304+P340, P305+P351+P338, P319, P330, P337+P317, P370+P378, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

Danger

H272 (100%): May intensify fire; oxidizer [Danger Oxidizing liquids; Oxidizing solids]

P210, P220, P261, P264, P264+P265, P270, P271, P273, P280, P301+P317, P304+P340, P305+P351+P338, P319, P330, P337+P317, P370+P378, P391, P403+P233, P405, and P501 (click each P-code to see the statement)

1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3-dichloro- is listed on the EPA's Chemical Data Reporting (CDR) system. Manufacturers and importers of 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3-dichloro- are required to report information about their production and use of this chemical to the EPA under the Toxic Substances Control Act (TSCA). (40 eCFR Part 711)

1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3-dichloro-: HSNO Approval: HSR004070 Approved with controls

The New Jersey Worker and Community Right to Know Act requires public and private employers to provide information about hazardous substances at their workplaces. (N.J.S.A. 34:5A-1 et. seq.)

Excerpt from ERG Guide 140 [Oxidizers]:

CAUTION: Ammonium nitrate products may explode if involved in fire or contaminated with hydrocarbons (fuels), organic matter, other contaminants or when hot molten and contained. Treat as an explosive (GUIDE 112).

Excerpt from ERG Guide 140 [Oxidizers]:

· Inhalation, ingestion or contact (skin, eyes) with vapors or substance may cause severe injury, burns or death.

An oxidzer that can ignite organic materials; An eye irritant; [Hawley] A strong skin, eye, and respiratory tract irritant; [HSDB] May react with water evolving chlorine gas; [CAMEO] An eye and respiratory tract irritant; [eChemPortal: ESIS] When dissolved in water, all chlorinated isocyanurates form hypochlorous acid, a weak acid and oxidizing agent; An eye irritant; [EPA REDs] See Sodium dichloroisocyanurate.

USEPA/Office of Pesticide Programs; Reregistration Eligibility Decision Document - Chlorinated Isocyanurates (September 1992). The RED summarizes the risk assessment conclusions and outlines any risk reduction measures necessary for the pesticide to continue to be registered in the U.S.[Available from, as of October 7, 2009: http://www.epa.gov/pesticides/reregistration/status.htm]

Residues of the following chemical substances are exempted from the requirement of a tolerance when used in accordance with good manufacturing practice as ingredients in an antimicrobial pesticide formulation, provided that the substance is applied on a semi-permanent or permanent food-contact surface (other than being applied on food packaging) with adequate draining before contact with food. ... (c) The following chemical substances when used as ingredients in an antimicrobial pesticide formulation may be applied to: Food-processing equipment and utensils. 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3-dichloro- is included on this list. Limit: When ready for use, the end-use concentration of all di- or trichloroisocyanuric acid chemicals in the solution is not to exceed 100 ppm determined as total available chlorine.

The Agency has sufficient information on the health effects of the chlorinated isocyanurates and on their potential for causing adverse effects in fish and wildlife and the environment for all uses registered for these chemicals. The Agency therefore concludes that products containing the chlorinated isocyanurates for these uses are eligible for reregistration. Only product chemistry data on certain manufacturing use products are still needed. The Agency has determined that the chlorinated isocyanurate products, labeled and used as specified in this Reregistration Eligibility Document, will not pose unreasonable risks or adverse effects to humans or the environment.

As the federal pesticide law FIFRA directs, EPA is conducting a comprehensive review of older pesticides to consider their health and environmental effects and make decisions about their continued use. Under this pesticide reregistration program, EPA examines newer health and safety data for pesticide active ingredients initially registered before November 1, 1984, and determines whether the use of the pesticide does not pose unreasonable risk in accordance to newer saftey standards, such as those described in the Food Quality Protection Act of 1996. Sodium dichloroisocyanurate is found on List A, which contains most pesticides that are used on foods and, hence, have a high potential for human exposure. List A consists of the 194 chemical cases (or 350 individual active ingredients) for which EPA issued registration standards prior to FIFRA '88. Case No: 0569; Pesticide type: antimicrobial; Registration Standard Date: 5/20/88 PB88-220660; Case Status: RED Approved 09/02; OPP has made a decision that some/all uses of the pesticide are eligible for reregistration, as reflected in a Reregistration Eligibility Decision (RED) document .; Active ingredient (AI): dichloroisocyanuric acid; Data Call-in (DCI) Date(s): 5/7/93; AI Status: OPP has completed a Reregistration Eligibility Decision (RED) for the case/AI.

· CALL 911. Then call emergency response telephone number on shipping paper. If shipping paper not available or no answer, refer to appropriate telephone number listed on the inside back cover.

· Keep combustibles (wood, paper, oil, etc.) away from spilled material.

EYES: First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

General First Aid:

Use water spray to cool containers exposed to fire and massive quantities of water to dilute material involved in fire or spilled from containers ... Personal protection: wear full protective clothing.

If material on fire or involved in fire: Flood with water. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible. /Dichloroisocyanuric acid, dry or salts/

Evacuation: If fire becomes uncontrollable - consider evacuation of one-half (1/2) mile radius. /Dichloroisocyanuric acid, dry or salts/

Protect against phys damage. Store in cool, dry, well-ventilated place away from flammable liq, combustible materials, and oxidizable materials. Drums may rupture if contents are exposed to heat or become contaminated or wet. Drums should be palletized to prevent wetting from floor washings or drainage. Avoid prolonged storage in unventilated areas at summer temperatures.

Protect containers against physical damage. Store in cool, dark, well ventilated place away from combustible liquid, easily combustible materials, or oxidizable materials. Drum may burst by heat, contamination of contents or absorbing of water. Palette should be laid under drum to protect from moisture. Avoid storage for extended periods in unventilated place during summer season.

TERRESTRIAL FATE: Based on a classification scheme(1), an estimated Koc value of 17(SRC), determined from a structure estimation method(2), indicates that dichloroisocyanuric acid is expected to have very high mobility in soil(SRC). The pKa of dichloroisocyanuric acid is 3.75(3), indicating that this compound will exist almost entirely in the anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(4). Volatilization from moist soil is not expected because the acid exists as an anion and anions do not volatilize(SRC). Dichloroisocyanuric acid is not expected to volatilize from dry soil surfaces(SRC) based upon an estimated vapor pressure of 2.0X10-9 mm Hg at 25 °C(SRC), determined from a fragment constant method(5). Biodegradation data for dichloroisocyanuric acid in the terrestrial environment were not available(SRC, 2009).

AQUATIC FATE: Based on a classification scheme(1), an estimated Koc value of 17(SRC), determined from a structure estimation method(2), indicates that dichloroisocyanuric acid is not expected to adsorb to suspended solids and sediment(SRC). A pKa of 3.75(3) indicates dichloroisocyanuric acid will exist almost entirely in the anion form at pH values of 5 to 9 and therefore volatilization from water surfaces is not expected to be an important fate process(4). According to a classification scheme(5), an estimated BCF of 3.3(SRC), from an estimated log Kow of 1.28(6) and a regression-derived equation(7), suggests the potential for bioconcentration in aquatic organisms is low(SRC). Dichloroisocyanuric acid is expected to undergo hydrolysis in the environment since this compound contains functional groups that hydrolyze under environmental conditions(8). Biodegradation data for dichloroisocyanuric acid in the aquatic environment were not available(SRC, 2009).

ATMOSPHERIC FATE: According to a model of gas/particle partitioning of semivolatile organic compounds in the atmosphere(1), dichloroisocyanuric acid, which has an estimated vapor pressure of 2.0X10-9 mm Hg at 25 °C(SRC), determined from a fragment constant method(2), is expected to exist solely in the particulate phase in the ambient atmosphere. Particulate-phase dichloroisocyanuric acid may be removed from the air by wet or dry deposition(SRC). Dichloroisocyanuric acid does not contains chromophores that absorb at wavelengths >290 nm(3) and therefore is not expected to be susceptible to direct photolysis by sunlight(SRC).

Residues of the following chemical substances are exempted from the requirement of a tolerance when used in accordance with good manufacturing practice as ingredients in an antimicrobial pesticide formulation, provided that the substance is applied on a semi-permanent or permanent food-contact surface (other than being applied on food packaging) with adequate draining before contact with food. ... (c) The following chemical substances when used as ingredients in an antimicrobial pesticide formulation may be applied to: Food-processing equipment and utensils. 1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3-dichloro- is included on this list. Limit: When ready for use, the end-use concentration of all di- or trichloroisocyanuric acid chemicals in the solution is not to exceed 100 ppm determined as total available chlorine.

The Agency has sufficient information on the health effects of the chlorinated isocyanurates and on their potential for causing adverse effects in fish and wildlife and the environment for all uses registered for these chemicals. The Agency therefore concludes that products containing the chlorinated isocyanurates for these uses are eligible for reregistration. Only product chemistry data on certain manufacturing use products are still needed. The Agency has determined that the chlorinated isocyanurate products, labeled and used as specified in this Reregistration Eligibility Document, will not pose unreasonable risks or adverse effects to humans or the environment.

As the federal pesticide law FIFRA directs, EPA is conducting a comprehensive review of older pesticides to consider their health and environmental effects and make decisions about their continued use. Under this pesticide reregistration program, EPA examines newer health and safety data for pesticide active ingredients initially registered before November 1, 1984, and determines whether the use of the pesticide does not pose unreasonable risk in accordance to newer saftey standards, such as those described in the Food Quality Protection Act of 1996. Sodium dichloroisocyanurate is found on List A, which contains most pesticides that are used on foods and, hence, have a high potential for human exposure. List A consists of the 194 chemical cases (or 350 individual active ingredients) for which EPA issued registration standards prior to FIFRA '88. Case No: 0569; Pesticide type: antimicrobial; Registration Standard Date: 5/20/88 PB88-220660; Case Status: RED Approved 09/02; OPP has made a decision that some/all uses of the pesticide are eligible for reregistration, as reflected in a Reregistration Eligibility Decision (RED) document .; Active ingredient (AI): dichloroisocyanuric acid; Data Call-in (DCI) Date(s): 5/7/93; AI Status: OPP has completed a Reregistration Eligibility Decision (RED) for the case/AI.

Both s-triazine-2,4,6(1H,3H,5H)-trione, 1,3,5-trichloro- and s-triazine-2,4,6(1H,3H,5H)-trione, 1,3-dichloro-, sodium salt are unstable in the body (particularly the stomach) because the available chlorine is rapidly reduced. Cyanuric acid (or its monosodium salt) is the degradation product from both products.

Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.

Agents used in the prophylaxis or therapy of VIRUS DISEASES. Some of the ways they may act include preventing viral replication by inhibiting viral DNA polymerase; binding to specific cell-surface receptors and inhibiting viral penetration or uncoating; inhibiting viral protein synthesis; or blocking late stages of virus assembly.

Substances used on inanimate objects that destroy harmful microorganisms or inhibit their activity. Disinfectants are classed as complete, destroying SPORES as well as vegetative forms of microorganisms, or incomplete, destroying only vegetative forms of the organisms. They are distinguished from ANTISEPTICS, which are local anti-infective agents used on humans and other animals. (From Hawley&apos;s Condensed Chemical Dictionary, 11th ed)

Used in household dry bleaches, dishwashing compounds, scouring powders, and detergent sanitizers; Also used as a replacement for calcium hypochlorite, a swimming pool disinfectant, and a slimicide on heat exchangers of recirculating cooling systems; [HSDB]

EPA Pesticide Fact Sheet: Chorinated Isocyanurates

Using Disinfectants or Biocides [Category: Clean]

For dichloroisocyanuric acid (USEPA/OPP Pesticide Code: 081401) ACTIVE products with label matches. /SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses./

Disinfectant, sanitizer for food processing plants, medical and industrial facilities, and residential use.

In household dry bleaches, dishwashing compounds, scouring powders, and detergent sanitizers; replacement for calcium hypochlorite

2023: 10,000,000 - <50,000,000 lb

Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#5582]

Produced commercially by chlorination of disodium cyanurate, prepared by reaction of cyanuric acid and caustic in a 1:2 molar ratio. Prepared by reaction of cyanuric acid with trichloroisocyanuric acid, hypochlorous acid, or chlorine dioxide. Drying fine crystalline trichloroisocyanuric acid needles isolated from concentrated aqueous sodium chloride.

Wonder Tab: Active Ingredients 18.19% Dichloro-s-triazinetrione, 66.96% Trichloro-s-triazinetrione

Kitchen Klenzer: Active Ingredient 0.8% Dichloro-s-triazinetrione

Form: liquid soluble concentrate.

ACL-59

For more Formulations/Preparations (Complete) data for Dichloroisocyanuric acid (9 total), please visit the HSDB record page.

All Other Basic Organic Chemical Manufacturing

1,3,5-Triazine-2,4,6(1H,3H,5H)-trione, 1,3-dichloro-: ACTIVE

Dichloroisocyanuric acid was more effective against Pseudomonas aeruginosa, Staphylococcus aureus, and sporulating Bacillus subtilis and Candida albicans than against Shigella flexneri or Escherichia coli.