Elastase

HCID 168009926CAS 81295-09-2
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Grundinformationen

Standard-SMILES
C=CC=C1CC(O)CCC1=C.C=CC=C1CC(O)CCC1=C
InChIKey
DXPFIOMVMNHFEU-UHFFFAOYSA-N
Summenformel
C20H28O2
Durchschnittliche Molmasse
300,4 g/mol

Namen und Bezeichner

Bevorzugter Name
Elastase
IUPAC
4-methylidene-3-prop-2-enylidenecyclohexan-1-ol
Lokaler Name
Elastase
Englischer Name
Elastase (human leucocytes)
Molmasse
0

Namen und Synonyme

Elastase9004-06-2Elastase [JAN]Pancreatopeptidase ERefChem:590675Peptidase, pancreato-, EMatrix metalloproteinase-12Proteinase, bone marrow serineMMP 12DTXSID601010856EINECS 232-670-7E.C. 3.4.4.7
Weitere Namen anzeigen
elastase from human leukocytesELA2ELANEelaszymEiastaseElastase-2e.c.3.4.4.7Elastase ESEC 3.4.21.37EC 3.4.21.36
E.C. 3.4.2.1.11E.C. 3.4.21.11E.C. 3.4.21.36E.C. 3.4.21.37E.C. 3.4.24.65232-670-7(3Z)-4-methylidene-3-prop-2-enylidenecyclohexan-1-ol81295-09-2

Datenbank-Bezeichner

CAS
81295-09-2、9004-06-2
PubChem CID
168009926
EC Number
232-670-7、279-720-4

Eigenschaften

Berechnete Struktureigenschaften

Polarare Oberfläche (TPSA)
40,5 Ų
H-Brücken-Donoren
2
H-Brücken-Akzeptoren
2
Frei drehbare Bindungen
2
Schwere Atome
22

Physikochemische Eigenschaften

storage temp.
-20 °C · -20°C
Aggregatzustand
lyophilized powder
Farbe
White to off-white
Biologische Quelle
rabbit
Specific Activity
50 units/mg · ≥50units/mg protein (Bradford)
CAS Datenbank
9004 · 9004-06-2

Sicherheit und Regulatorisches

GHS-Klassifizierung

GHS Classification · 4 Einträge

Danger

H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]

P233, P260, P261, P264, P264+P265, P271, P280, P284, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P342+P316, P362+P364, P403, P403+P233, P405, and P501 (click each P-code to see the statement)

Aggregated GHS information provided per 39 reports by companies from 2 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

Gefahrenhinweise

Regulatory Information · 2 Einträge

XU - indicates a substance exempt from reporting under the Chemical Data Reporting Rule, (40 CFR 711).

Elastase: Does not have an individual approval but may be used under an appropriate group standard

Hazard Classes and CategoriesSkin Irrit. 2 (100%)

Sicherheitsdaten

F
3-10
wgk
3
tsca
TSCA listed
hazard_code
B
Speicherklasse
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2Resp. Sens. 1Skin Irrit. 2STOT SE 3

Chemie und Industrie

Verwendung und Herstellung

General Manufacturing InformationElastase: ACTIVE
Anwendungen · 1 Eintrag

VerwendenElastase from human leukocytes has been used: to measure serum elastase activityin proteolytic digestion of fibronectin and salivary glandsin neutrophil elastase (NE) activity assaycell-free NE digestion of E-cadherinscratch wound assayin a study that determined that fragments of Nle3-angiotensin(1-7) accelerate healing in dermal modelsElastase has been used to digest fibronectin. The results were compared with fibronectin digestion by crude human leukocyte homogenate to examine the presence of fibronectin peptides in saliva of patients with Sjgren′s syndrome. It has also been used as a reference to determine the elastase activity in cell lysates. This study examined the effect of all-trans retinoic acid on procoagulant and fibrinolytic activities of cultured blast cells. These blast cells were from patients with acute promyelocytic leukemia.

Vor- und nachgelagerte Produkte

Anbieter11 Anbieter

南通飞宇生物科技有限公司0513-68819626 15152877458 · [email protected]
上海康朗生物科技有限公司021-61998208 18217752821 · [email protected]
上海晶抗生物工程有限公司021-54721350 13524668266 · [email protected]
陕西缔都医药化工有限公司029-81024372 17792795018 · [email protected]
上海谱科生物技术有限公司021-64705760 18027310741 · [email protected]

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