HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-Hydroxybenzohydrazid
4-HYDROXYBENZOHYDRAZIDE · PAHBAH · DK841 · NSC647 · NSC 647 · ST5046190 · 4OHPhCON2 · AIDS009023
Identifikatoren & physikalische Daten
| CAS No. | 5351-23-5 |
|---|---|
| Summenformel | C7H8N2O2 |
| Durchschnittliche Molmasse | 152,15 g/mol |
| Monoisotopische Masse | 152,0585775 g/mol |
| SMILES | NNC(=O)c1ccc(O)cc1 |
| InChIKey | ZMZGIVVRBMFZSG-UHFFFAOYSA-N |
| PubChem CID | 1742 |
| ChEMBL | CHEMBL124267 |
| ChEBI | CHEBI:195425 |
| EC No. | 226-326-5 |
| DTXSID | DTXSID90201721 |
| Lokaler Name | 4-Hydroxybenzohydrazid |
Chemische & physikalische Eigenschaften
| XLogP | -0,3 |
|---|---|
| Polarare Oberfläche (TPSA) | 75,4 |
| H-Brücken-Donoren | 3 |
| H-Brücken-Akzeptoren | 3 |
| Frei drehbare Bindungen | 1 |
| Schwere Atome | 11 |
| Formalladung | 0 |
| Komplexität | 141 |
| LogP (Verteilungskoeffizient) | -0.33 |
| Löslichkeit | 22.4 [ug/mL] (The mean of the results at pH 7.4)26.5g/l |
| Endocrine Disruptors | Potential endocrine disrupting compound |
| Schmelzpunkt | 264-266 °C (dec.)(lit.) |
| Siedepunkt | 274.61°C (rough estimate) |
| Dichte | 1.2804 (rough estimate) |
| Brechungsindex | 1.5200 (estimate) |
| Lagerbedingungen | Store at +15°C to +25°C. |
| Aggregatzustand | Fine Crystalline Powder |
| pKa (Säurekonstante) | 8.57±0.15(Predicted) |
| Farbe | White to slightly beige |
| Biologische Quelle | synthetic |
| BRN | 473052 |
| InChI | 1S/C7H8N2O2/c8-9-7(11)5-1-3-6(10)4-2-5/h1-4,10H,8H2,(H,9,11) |
| InChIKey | ZMZGIVVRBMFZSG-UHFFFAOYSA-N |
| SMILES | NNC(=O)c1ccc(O)cc1 |
| CAS Datenbank | 5351-23-5(CAS DataBase Reference) |
| NIST chemische Informationen | P-hydroxybenzoic acid, hydrazide(5351-23-5) |
Sicherheit & Vorschriften
| GHS-Einstufung | WarningH315 (98%): Causes skin irritation [Warning Skin corrosion/irritation]P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 (click each P-code to see the statement)Aggregated GHS information provided per 49 reports by companies from 7 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies. |
|---|---|
| Regulatorische Informationen | Status: Active Update: 08-03-2018 https://echa.europa.eu/registration-dossier/-/registered-dossier/22867Benzoic acid, 4-hydroxy-, hydrazide: Does not have an individual approval but may be used under an appropriate group standard |
| Hazard Classes and Categories | Skin Irrit. 2 (98%) |
| Wassergefährdungsklasse (WGK) | 3 |
| Zollcode | 29280090 |
| R-Sätze (R) | 36/37/38 |
| Gefahrensymbole | Xi,C |
| Sicherheitshinweise (S) | 26-36-37/39 |
| Gefahrenklasse | IRRITANTEye Irrit. 2Skin Irrit. 2STOT SE 3 |
| Lagerklasse | 11 - Combustible Solids |
Anwendungen & Verwendung
Verwenden
4-Hydroxybenzhydrazide is a reagent for the rapid automated determination of serum glucose.It can be used as an indicator for the determination of carbohydrates. The acid-hydrolyzable side chains of tissue (liver) bound 4-Hydroxybenzhydrazide can be used as markers to monitor its residues in chickens.